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== Splenomegaly differential: ==
 
{| class="wikitable"
! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Category
! colspan="2" rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Disease
! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Etiology
! colspan="12" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Clinical manifestations
! colspan="10" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Para−clinical findings
! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Gold standard
! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Associated findings
|-
! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Demography
! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |History
! colspan="5" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Symptoms
! colspan="5" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Signs
! colspan="9" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab Findings
! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging
|-
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Fever
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Fatigue
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Weight loss
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |SOB
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Bleeding
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |BP
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |JVP
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Jaundice
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Ascites
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Other
! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |CBC
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |PS
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Iron
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |LFT
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |PT/PTT
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |BUN/Cr
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |UA
|-
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |WBC
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Hb
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Plt
|-
! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Congestive
! colspan="2" align="center" style="background:#DCDCDC;" |Cirrhosis
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! colspan="2" align="center" style="background:#DCDCDC;" |Heart failure
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! colspan="2" align="center" style="background:#DCDCDC;" |Thrombosis of portal, hepatic, or splenic veins
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! rowspan="8" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Malignancy
! colspan="2" align="center" style="background:#DCDCDC;" |Lymphoma
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! colspan="2" align="center" style="background:#DCDCDC;" |Leukemias
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! colspan="2" align="center" style="background:#DCDCDC;" |Polycythemia Vera
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! colspan="2" align="center" style="background:#DCDCDC;" |Multiple myeloma
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! colspan="2" align="center" style="background:#DCDCDC;" |Essential thrombocythemia
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! colspan="2" align="center" style="background:#DCDCDC;" |Primary myelofibrosis
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! colspan="2" align="center" style="background:#DCDCDC;" |Primary splenic tumors
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! colspan="2" align="center" style="background:#DCDCDC;" |Metastatic solid tumors
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!Category
! colspan="2" |Disease
!Etiology
!Demography
!History
!Fever
!Fatigue
!Weight loss
!SOB
!Bleeding
!BP
!JVP
!Jaundice
!Ascites
!Other
!WBC
!Hb
!Plt
!PS
!Iron
!LFT
!PT/PTT
!BUN/Cr
!UA
!Imaging
!Gold standard
!Associated findings
|-
! rowspan="6" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Infection
! align="center" style="background:#DCDCDC;" |Viral
! align="center" style="background:#DCDCDC;" |Hepatitis, infectious mononucleosis, cytomegalovirus
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! align="center" style="background:#DCDCDC;" |Bacterial
! align="center" style="background:#DCDCDC;" |Salmonella, Brucella, tuberculosis
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! rowspan="2" align="center" style="background:#DCDCDC;" |Parasitic
! align="center" style="background:#DCDCDC;" |Malaria, schistosomiasis, toxoplasmosis
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! align="center" style="background:#DCDCDC;" |Kala-azar (visceral leishmaniasis)
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! colspan="2" align="center" style="background:#DCDCDC;" |Infective endocarditis
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! colspan="2" align="center" style="background:#DCDCDC;" |Fungal
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! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Inflammation
! colspan="2" align="center" style="background:#DCDCDC;" |Sarcoid
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! colspan="2" align="center" style="background:#DCDCDC;" |Serum sickness
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! colspan="2" align="center" style="background:#DCDCDC;" |Systemic lupus erythematosus
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! colspan="2" align="center" style="background:#DCDCDC;" |Felty syndrome
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!Category
! colspan="2" |Disease
!Etiology
!Demography
!History
!Fever
!Fatigue
!Weight loss
!SOB
!Bleeding
!BP
!JVP
!Jaundice
!Ascites
!Other
!WBC
!Hb
!Plt
!PS
!Iron
!LFT
!PT/PTT
!BUN/Cr
!UA
!Imaging
!Gold standard
!Associated findings
|-
! rowspan="6" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Infiltrative
! colspan="2" align="center" style="background:#DCDCDC;" |Gaucher disease
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! colspan="2" align="center" style="background:#DCDCDC;" |Niemann-Pick disease
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! colspan="2" align="center" style="background:#DCDCDC;" |Amyloidosis
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! colspan="2" align="center" style="background:#DCDCDC;" |Langerhans cell histiocytosis
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! colspan="2" align="center" style="background:#DCDCDC;" |Hemophagocytic lymphohistiocytosis
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! colspan="2" align="center" style="background:#DCDCDC;" |Rosai-Dorfman disease
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! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Hematologic (hypersplenic) states
! colspan="2" align="center" style="background:#DCDCDC;" |Hemolytic anemia
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! colspan="2" align="center" style="background:#DCDCDC;" |Sickle cell disease
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! colspan="2" align="center" style="background:#DCDCDC;" |Granulocyte colony-stimulating factor
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! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Category
! colspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Disease
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Etiology
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Demography
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |History
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Fever
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Fatigue
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Weight loss
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |SOB
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Bleeding
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |BP
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |JVP
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Jaundice
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Ascites
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Other
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |WBC
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Hb
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Plt
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |PS
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Iron
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |LFT
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |PT/PTT
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |BUN/Cr
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |UA
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Gold standard
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Associated findings
|}

Latest revision as of 15:53, 28 September 2018