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| {{CMG}}; {{AE}} {{Anmol}} | | {{CMG}}; {{AE}} {{Anmol}} |
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| ==Differential NHL== | | ==Tables== |
| | | {| class="wikitable" |
| {| | | |+ |
| |- style="background: #4479BA; color: #FFFFFF; text-align: center;"
| | !Diagnosis |
| ! colspan="3" rowspan="4" |Diseases
| | !Lab findings |
| | colspan="6" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;" |'''Clinical manifestations'''
| | ! |
| ! colspan="3" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Para-clinical findings | | ! |
| ! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Pathogonomic finding | |
| |- | | |- |
| | colspan="6" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |'''Symptoms'''
| | ! |
| | ! |
| | ! |
| | ! |
| |- | | |- |
| ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab Findings
| |
| ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Images
| |
| ! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Biopsy
| |
| Histopathology
| |
| |-
| |
| ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lymphadenopathy
| |
| ! colspan="1" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Fever
| |
| ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Weight loss
| |
| ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Night Sweats
| |
| ! colspan="1" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Rash
| |
| ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Other symptoms
| |
| ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab 1
| |
| ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging 1
| |
| |-
| |
| | colspan="3" |Non-Hodgkins lymphoma
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * painless
| |
| * localized or generalized
| |
| | style="background: #F5F5F5; padding: 5px;" | +
| |
| | style="background: #F5F5F5; padding: 5px;" | +
| |
| | style="background: #F5F5F5; padding: 5px;" | +
| |
| | style="background: #F5F5F5; padding: 5px;" | +
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Presents with "B" symptoms
| |
|
| |
| * Constant [[Fatigue (physical)|fatigue]]
| |
| * [[Shortness of breath]] and Cough
| |
| * [[Abdominal pain]] or swelling
| |
| * [[Constipation]]
| |
| * [[Nausea]] and[[vomiting]].
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| |-
| |
| | rowspan="8" |'''INFECTIONS'''
| |
| | rowspan="2" style="background: #DCDCDC; padding: 5px; text-align: center;" |Bacteria
| |
| |Syphilis
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * painless
| |
| * localized
| |
| | +
| |
| |<nowiki>-</nowiki>
| |
| | -
| |
| | +
| |
| |Primary syphilis:
| |
| * Chancer
| |
| Secondary syphilis:
| |
| * Rash
| |
| * Condylomata lata
| |
| * Patchy [[alopecia]]
| |
| Tertiary syphilis
| |
| * Gumma
| |
| * Organ system involvement
| |
| |
| |
| * Darkfield microscopy to detect ''[[T. pallidum]].''
| |
|
| |
| * Nontreponemal tests (e.g., [[VDRL]]<nowiki/>and [[RPR]] )
| |
| * Treponemal tests (e.g. [[FTA-ABS]], the TP-PA assay
| |
| |
| |
| |
| |
| |Painless clean base chancre.
| |
| |-
| |
| |Brucellosis
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Painful
| |
| | style="background: #F5F5F5; padding: 5px;" | +
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | +
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Abdominal pain
| |
| * hepatosplenomegaly
| |
| * arthritis
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * [[Brucella|''Brucella'']] is most commonly isolated from blood cultures
| |
|
| |
| * positive titer of anti-[[Brucella|b''rucella'']] [[antibodies]] on serological testing
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |[[Night sweats]], often with characteristic smell, likened to wet hay
| |
| |-
| |
| | rowspan="4" |Viral
| |
| |infectious mononucleosis
| |
| |
| |
| * painful
| |
| |<nowiki>+</nowiki>
| |
| |<nowiki>-</nowiki>
| |
| |<nowiki>-</nowiki>
| |
| |<nowiki>+</nowiki>
| |
| |
| |
| * low-grade [[fever]]<nowiki/>without [[chills]]
| |
| * [[sore throat]],
| |
| * white patches on [[tonsils]] and back of the throat,
| |
| * [[muscle weakness]]
| |
| * [[fatigue]]
| |
| * [[petechial hemorrhage]]
| |
| | | | | |
| | | | | |
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| | | | | |
| |- | | |- |
| |CMV
| |
| |
| |
| |<nowiki>+</nowiki>
| |
| |<nowiki>-</nowiki>
| |
| |<nowiki>-</nowiki>
| |
| |<nowiki>+</nowiki>
| |
| |
| |
| | | | | |
| | | | | |
Line 128: |
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| | | | | |
| |- | | |- |
| |HIV
| |
| | | | | |
| * Painful or painless
| |
| |<nowiki>-</nowiki>
| |
| |<nowiki>+</nowiki>
| |
| |<nowiki>-</nowiki>
| |
| |<nowiki>-</nowiki>
| |
| | | | | |
| | | | | |
| | | | | |
| |
| |
| |
| |
| |-
| |
| |Cat scratch disease
| |
| |
| |
| |<nowiki>+</nowiki>
| |
| |<nowiki>-</nowiki>
| |
| |<nowiki>-</nowiki>
| |
| |<nowiki>+</nowiki>
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |-
| |
| |Mycobacteria
| |
| |Tuberculosis
| |
| |
| |
| * Painful
| |
| |<nowiki>+</nowiki>
| |
| |<nowiki>+</nowiki>
| |
| |<nowiki>+</nowiki>
| |
| |<nowiki>+</nowiki>
| |
| |
| |
| * Prior history of residence in an endemic area.
| |
| * Chronic [[cough]], [[weight loss]], [[hemoptysis]]
| |
| |
| |
| * [[PCR]] of [[CSF]] for [[tuberculosis]]
| |
| * Mycobacterial culture of CSF
| |
| * Brain biopsy for [[acid-fast bacilli]] staining
| |
| * Culture and acid stain positive for [[acid-fast bacilli]]
| |
| * CXR shows cavitations.
| |
| |
| |
| |
| |
| |Gohn's focus
| |
| |-
| |
| |Parasite
| |
| |Toxoplasmosis
| |
| |
| |
| |
| |
| |<nowiki>-</nowiki>
| |
| |<nowiki>-</nowiki>
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |- style="background: #4479BA; color: #FFFFFF; text-align: center;"
| |
| ! colspan="3" |Diseases
| |
| !Lymphadenopathy
| |
| ! colspan="1" rowspan="1" |Fever
| |
| !Weight loss
| |
| !Night sweats
| |
| ! colspan="1" rowspan="1" |Rash
| |
| !Other symptoms
| |
| !Lab 1
| |
| !Imaging 1
| |
| !Biopsy
| |
| Histopathology
| |
| !Pathogonomical
| |
| findings
| |
| |-
| |
| | rowspan="3" |'''AUTOIMMUNE'''
| |
| | colspan="2" style="background: #DCDCDC; padding: 5px; text-align: center;" |Systemic lupus erythematosus
| |
| | style="background: #F5F5F5; padding: 5px;" |painless
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | +
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * [[ESR]]
| |
| * [[CRP]]<nowiki/>elevated
| |
| * [[ANA]] positive
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |[[Malar rash]] and [[photosensitivity]]
| |
| |-
| |
| | colspan="2" style="background: #DCDCDC; padding: 5px; text-align: center;" |Sjögren's syndrome
| |
| | style="background: #F5F5F5; padding: 5px;" |Painless
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | +
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * [[Xerosis]]
| |
| * Scaly skin
| |
| * Annular [[erythema]]
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |[[Keratoconjunctivitis sicca]]
| |
| |-
| |
| | colspan="2" style="background: #DCDCDC; padding: 5px; text-align: center;" |Sarcoidosis
| |
| | style="background: #F5F5F5; padding: 5px;" |painless
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| |
| |
| |<nowiki>-</nowiki>
| |
| |<nowiki>-</nowiki>
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |- style="background: #4479BA; color: #FFFFFF; text-align: center;"
| |
| ! colspan="3" |Diseases
| |
| !Lymphadenopathy
| |
| ! colspan="1" rowspan="1" |Fever
| |
| !Weight loss
| |
| !Night sweats
| |
| ! colspan="1" rowspan="1" |Rash
| |
| !Other symptoms
| |
| !Lab 1
| |
| !Imaging 1
| |
| !Biopsy
| |
| Histopathology
| |
| !Pathogonomical
| |
| findings
| |
| |-
| |
| |-
| |
| | rowspan="6" |'''NEOPLASIA'''
| |
| | colspan="2" style="background: #DCDCDC; padding: 5px; text-align: center;" |Hodgkin's disease
| |
| | style="background: #F5F5F5; padding: 5px;" |painless
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | +
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * [[ESR]]
| |
| * [[CRP]]<nowiki/>elevated
| |
| * [[ANA]] positive
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |[[Malar rash]] and [[photosensitivity]]
| |
| |-
| |
| | colspan="2" style="background: #DCDCDC; padding: 5px; text-align: center;" |'''Chronic lymphocytic leukemia'''
| |
| | style="background: #F5F5F5; padding: 5px;" |Painless
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | +
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * [[Xerosis]]
| |
| * Scaly skin
| |
| * Annular [[erythema]]
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |[[Keratoconjunctivitis sicca]]
| |
| |-
| |
| | colspan="2" style="background: #DCDCDC; padding: 5px; text-align: center;" |'''Small cell carcinoma of the lung'''
| |
| | style="background: #F5F5F5; padding: 5px;" |painless
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| |-
| |
| | colspan="2" style="background: #DCDCDC; padding: 5px; text-align: center;" |'''Small cell carcinoma of the lung'''
| |
| | style="background: #F5F5F5; padding: 5px;" |painless
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| |-
| |
| | colspan="2" style="background: #DCDCDC; padding: 5px; text-align: center;" |'''Small cell carcinoma of the lung'''
| |
| | style="background: #F5F5F5; padding: 5px;" |painless
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| |-
| |
| | colspan="2" style="background: #DCDCDC; padding: 5px; text-align: center;" |'''Small cell carcinoma of the lung'''
| |
| | style="background: #F5F5F5; padding: 5px;" |painless
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| |-
| |
| | rowspan="3" |'''NEOPLASIA'''
| |
| | colspan="2" style="background: #DCDCDC; padding: 5px; text-align: center;" |'''Small cell carcinoma of the lung'''
| |
| | style="background: #F5F5F5; padding: 5px;" |painless
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| |} | | |} |
|
| |
|
| ==References== | | ==References== |
| {{reflist|2}} | | {{reflist|2}} |