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{{Burkitt's lymphoma}}
{{Burkitt's lymphoma}}


{{CMG}}; {{AE}} {{AS}}
{{CMG}}; {{AE}} {{AS}}, {{kakbar}}


==Overview==
==Overview==
Common physical examination findings of Burkitt's lymphoma include [[fever]], [[Lymphadenopathy|peripheral lymphadenopathy]] and [[Lymphadenopathy|central lymphadenopathy]].
Common [[physical examination]] findings of Burkitt's lymphoma include [[fever]], [[Lymphadenopathy|peripheral lymphadenopathy]] and [[Lymphadenopathy|central lymphadenopathy]].
==Physical Examination==
==Physical Examination==
The following physical examination findings may be present among patients with Burkitt's lymphoma:<ref>Burkitt lymphoma. MedlinePlus. https://www.nlm.nih.gov/medlineplus/ency/article/001308.htm Accessed on October 5, 2015</ref>
The following [[physical examination]] findings may be present among patients with Burkitt's lymphoma:<ref>Burkitt lymphoma. MedlinePlus. https://www.nlm.nih.gov/medlineplus/ency/article/001308.htm Accessed on October 5, 2015</ref>
===Vitals===
===Vitals===
* [[Fever]] <ref name="pmid29465563">{{cite journal| author=Mărginean CO, Meliţ LE, Horvath E, Gozar H, Chinceşan MI| title=Non-Hodgkin lymphoma, diagnostic, and prognostic particularities in children - a series of case reports and a review of the literature (CARE compliant). | journal=Medicine (Baltimore) | year= 2018 | volume= 97 | issue= 8 | pages= e9802 | pmid=29465563 | doi=10.1097/MD.0000000000009802 | pmc=5842010 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29465563  }} </ref>
* [[Fever]] <ref name="pmid29465563">{{cite journal| author=Mărginean CO, Meliţ LE, Horvath E, Gozar H, Chinceşan MI| title=Non-Hodgkin lymphoma, diagnostic, and prognostic particularities in children - a series of case reports and a review of the literature (CARE compliant). | journal=Medicine (Baltimore) | year= 2018 | volume= 97 | issue= 8 | pages= e9802 | pmid=29465563 | doi=10.1097/MD.0000000000009802 | pmc=5842010 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29465563 }} </ref><ref name="pmid28890232">{{cite journal| author=Maier S, Bălaşa R, Bajko Z, Simu I, Horvath E| title=Complete progressive ophthalmoplegia and numb chin syndrome, the first clinical manifestations of a lethal abdominal Burkitt lymphoma. | journal=Neurol Neurochir Pol | year= 2017 | volume= 51 | issue= 6 | pages= 510-513 | pmid=28890232 | doi=10.1016/j.pjnns.2017.08.004 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28890232 }} </ref>
===HEENT===
===HEENT===
* [[Proptosis]]<ref name="pmid27894519">{{cite journal| author=de Freytas A, Rengel Ruiz M, España Gregori E| title=Proptosis as initial manifestation of Burkitt's lymphoma with orbital involvement. | journal=Arch Soc Esp Oftalmol | year= 2017 | volume= 92 | issue= 4 | pages= 178-180 | pmid=27894519 | doi=10.1016/j.oftal.2016.10.002 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27894519  }} </ref>
* [[Proptosis]]<ref name="pmid27894519">{{cite journal| author=de Freytas A, Rengel Ruiz M, España Gregori E| title=Proptosis as initial manifestation of Burkitt's lymphoma with orbital involvement. | journal=Arch Soc Esp Oftalmol | year= 2017 | volume= 92 | issue= 4 | pages= 178-180 | pmid=27894519 | doi=10.1016/j.oftal.2016.10.002 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27894519  }} </ref>
* Jaw mass<ref name="pmid26254375">{{cite journal| author=Sivolella S, Rizzo G, Valente M, Lumachi F| title=Sporadic Burkitt Lymphoma Mimicking Osteomyelitis of the Mandible Revealing Clinically Unsuspected HIV Infection. | journal=Anticancer Res | year= 2015 | volume= 35 | issue= 9 | pages= 4837-9 | pmid=26254375 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26254375  }} </ref>
* Jaw mass<ref name="pmid26254375">{{cite journal| author=Sivolella S, Rizzo G, Valente M, Lumachi F| title=Sporadic Burkitt Lymphoma Mimicking Osteomyelitis of the Mandible Revealing Clinically Unsuspected HIV Infection. | journal=Anticancer Res | year= 2015 | volume= 35 | issue= 9 | pages= 4837-9 | pmid=26254375 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26254375 }} </ref><ref name="pmid28680947">{{cite journal| author=El-Mallawany NK, Mutai M, Mtete I, Gopal S, Stanley CC, Wasswa P et al.| title=Beyond Endemic Burkitt Lymphoma: Navigating Challenges of Differentiating Childhood Lymphoma Diagnoses Amid Limitations in Pathology Resources in Lilongwe, Malawi. | journal=Glob Pediatr Health | year= 2017 | volume= 4 | issue=  | pages= 2333794X17715831 | pmid=28680947 | doi=10.1177/2333794X17715831 | pmc=5484428 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28680947 }} </ref>
* [[Lymphadenopathy|Cervical lymphadenopathy]]<ref name="pmid29157168">{{cite journal| author=Vora N, Haryee H, Dickson JC, Miller RF| title=Burkitt non-Hodgkin lymphoma presenting with mental neuropathy ('numb chin' syndrome) in an HIV-positive patient. | journal=Int J STD AIDS | year= 2018 | volume= 29 | issue= 6 | pages= 618-620 | pmid=29157168 | doi=10.1177/0956462417742562 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29157168  }} </ref>
* [[Lymphadenopathy|Cervical lymphadenopathy]]<ref name="pmid29157168">{{cite journal| author=Vora N, Haryee H, Dickson JC, Miller RF| title=Burkitt non-Hodgkin lymphoma presenting with mental neuropathy ('numb chin' syndrome) in an HIV-positive patient. | journal=Int J STD AIDS | year= 2018 | volume= 29 | issue= 6 | pages= 618-620 | pmid=29157168 | doi=10.1177/0956462417742562 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29157168  }} </ref>
===Thorax===
===Thorax===
* Thoracic masses suggestive of [[Lymphadenopathy|central lymphadenopathy]]<ref name="pmid18802952">{{cite journal| author=Orem J, Maganda A, Mbidde EK, Weiderpass E| title=Clinical characteristics and outcome of children with Burkitt lymphoma in Uganda according to HIV infection. | journal=Pediatr Blood Cancer | year= 2009 | volume= 52 | issue= 4 | pages= 455-8 | pmid=18802952 | doi=10.1002/pbc.21769 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18802952  }} </ref>
* [[Thoracic]] masses suggestive of [[Lymphadenopathy|central lymphadenopathy]]<ref name="pmid18802952">{{cite journal| author=Orem J, Maganda A, Mbidde EK, Weiderpass E| title=Clinical characteristics and outcome of children with Burkitt lymphoma in Uganda according to HIV infection. | journal=Pediatr Blood Cancer | year= 2009 | volume= 52 | issue= 4 | pages= 455-8 | pmid=18802952 | doi=10.1002/pbc.21769 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18802952  }} </ref>
===Abdomen===
===Abdomen===
* [[Abdominal mass]]es suggestive of [[Lymphadenopathy|central lymphadenopathy]]<ref name="pmid29892537">{{cite journal| author=Cho BH, Shin DH, Jung YH, Park HR| title=Widely disseminated sporadic Burkitt lymphoma initially presented as oral manifestations in a 6-year-old boy. | journal=J Oral Biol Craniofac Res | year= 2018 | volume= 8 | issue= 2 | pages= 140-142 | pmid=29892537 | doi=10.1016/j.jobcr.2018.02.001 | pmc=5993457 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29892537  }} </ref>
* [[Abdominal mass]]es suggestive of [[Lymphadenopathy|central lymphadenopathy]]<ref name="pmid29892537">{{cite journal| author=Cho BH, Shin DH, Jung YH, Park HR| title=Widely disseminated sporadic Burkitt lymphoma initially presented as oral manifestations in a 6-year-old boy. | journal=J Oral Biol Craniofac Res | year= 2018 | volume= 8 | issue= 2 | pages= 140-142 | pmid=29892537 | doi=10.1016/j.jobcr.2018.02.001 | pmc=5993457 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29892537 }} </ref><ref name="pmid29770187">{{cite journal| author=Okamoto T, Sekiya A, Daifu T, Doi R, Kobayashi H| title=Primary jejunal Burkitt lymphoma in a child: ultrasonic detection. | journal=J Surg Case Rep | year= 2018 | volume= 2018 | issue= 5 | pages= rjy090 | pmid=29770187 | doi=10.1093/jscr/rjy090 | pmc=5951082 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29770187 }} </ref>
* [[Ascites]]<ref name="pmid25612555">{{cite journal| author=Cordoba R, Alvarez B, Masso P, Gonzalez FA, Conejo L, Velasco D et al.| title=The utility of multiparametric seven-color flow cytometry in the detection of double hit lymphoma in ascitic fluid samples. | journal=Cytometry B Clin Cytom | year= 2016 | volume= 90 | issue= 6 | pages= 543-545 | pmid=25612555 | doi=10.1002/cyto.b.21227 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25612555  }} </ref>
* [[Ascites]]<ref name="pmid25612555">{{cite journal| author=Cordoba R, Alvarez B, Masso P, Gonzalez FA, Conejo L, Velasco D et al.| title=The utility of multiparametric seven-color flow cytometry in the detection of double hit lymphoma in ascitic fluid samples. | journal=Cytometry B Clin Cytom | year= 2016 | volume= 90 | issue= 6 | pages= 543-545 | pmid=25612555 | doi=10.1002/cyto.b.21227 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25612555  }} </ref>
===Extremities===
===Extremities===

Latest revision as of 23:15, 18 January 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2], Kamal Akbar, M.D.[3]

Overview

Common physical examination findings of Burkitt's lymphoma include fever, peripheral lymphadenopathy and central lymphadenopathy.

Physical Examination

The following physical examination findings may be present among patients with Burkitt's lymphoma:[1]

Vitals

HEENT

Thorax

Abdomen

Extremities

References

  1. ↑ Burkitt lymphoma. MedlinePlus. https://www.nlm.nih.gov/medlineplus/ency/article/001308.htm Accessed on October 5, 2015
  2. ↑ Mărginean CO, Meliţ LE, Horvath E, Gozar H, Chinceşan MI (2018). "Non-Hodgkin lymphoma, diagnostic, and prognostic particularities in children - a series of case reports and a review of the literature (CARE compliant)". Medicine (Baltimore). 97 (8): e9802. doi:10.1097/MD.0000000000009802. PMC 5842010. PMID 29465563.
  3. ↑ Maier S, Bălaşa R, Bajko Z, Simu I, Horvath E (2017). "Complete progressive ophthalmoplegia and numb chin syndrome, the first clinical manifestations of a lethal abdominal Burkitt lymphoma". Neurol Neurochir Pol. 51 (6): 510–513. doi:10.1016/j.pjnns.2017.08.004. PMID 28890232.
  4. ↑ de Freytas A, Rengel Ruiz M, España Gregori E (2017). "Proptosis as initial manifestation of Burkitt's lymphoma with orbital involvement". Arch Soc Esp Oftalmol. 92 (4): 178–180. doi:10.1016/j.oftal.2016.10.002. PMID 27894519.
  5. ↑ Sivolella S, Rizzo G, Valente M, Lumachi F (2015). "Sporadic Burkitt Lymphoma Mimicking Osteomyelitis of the Mandible Revealing Clinically Unsuspected HIV Infection". Anticancer Res. 35 (9): 4837–9. PMID 26254375.
  6. ↑ El-Mallawany NK, Mutai M, Mtete I, Gopal S, Stanley CC, Wasswa P; et al. (2017). "Beyond Endemic Burkitt Lymphoma: Navigating Challenges of Differentiating Childhood Lymphoma Diagnoses Amid Limitations in Pathology Resources in Lilongwe, Malawi". Glob Pediatr Health. 4: 2333794X17715831. doi:10.1177/2333794X17715831. PMC 5484428. PMID 28680947.
  7. ↑ Vora N, Haryee H, Dickson JC, Miller RF (2018). "Burkitt non-Hodgkin lymphoma presenting with mental neuropathy ('numb chin' syndrome) in an HIV-positive patient". Int J STD AIDS. 29 (6): 618–620. doi:10.1177/0956462417742562. PMID 29157168.
  8. ↑ Orem J, Maganda A, Mbidde EK, Weiderpass E (2009). "Clinical characteristics and outcome of children with Burkitt lymphoma in Uganda according to HIV infection". Pediatr Blood Cancer. 52 (4): 455–8. doi:10.1002/pbc.21769. PMID 18802952.
  9. ↑ Cho BH, Shin DH, Jung YH, Park HR (2018). "Widely disseminated sporadic Burkitt lymphoma initially presented as oral manifestations in a 6-year-old boy". J Oral Biol Craniofac Res. 8 (2): 140–142. doi:10.1016/j.jobcr.2018.02.001. PMC 5993457. PMID 29892537.
  10. ↑ Okamoto T, Sekiya A, Daifu T, Doi R, Kobayashi H (2018). "Primary jejunal Burkitt lymphoma in a child: ultrasonic detection". J Surg Case Rep. 2018 (5): rjy090. doi:10.1093/jscr/rjy090. PMC 5951082. PMID 29770187.
  11. ↑ Cordoba R, Alvarez B, Masso P, Gonzalez FA, Conejo L, Velasco D; et al. (2016). "The utility of multiparametric seven-color flow cytometry in the detection of double hit lymphoma in ascitic fluid samples". Cytometry B Clin Cytom. 90 (6): 543–545. doi:10.1002/cyto.b.21227. PMID 25612555.
  12. ↑ El-Mallawany NK, Wasswa P, Mtete I, Mutai M, Stanley CC, Mtunda M; et al. (2017). "Identifying opportunities to bridge disparity gaps in curing childhood cancer in Malawi: Malignancies with excellent curative potential account for the majority of diagnoses". Pediatr Hematol Oncol. 34 (5): 261–274. doi:10.1080/08880018.2017.1395934. PMID 29190181.


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