Pleomorphic adenoma classification: Difference between revisions

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{{Pleomorphic adenoma}}
{{Pleomorphic adenoma}}


{{CMG}}; {{AE}}  
{{CMG}}; {{AE}} {{M.N}}
==Overview==
==Overview==
There is no established system for the classification of [disease name].
Pleomorphic adenoma can be classified into 4 subgroups on the basis of [[histology]] appearance and [[stromal]] content into 4 groups. Subgroup 1, subgroup 2, subgroup 3, subgroup 4. It can also be classified based upon the component that predominates into 3 types, [[cellular]], [[stroma]] rich, and mixed type.
 
OR
 
[Disease name] may be classified according to [classification method] into [number] subtypes/groups: [group1], [group2], [group3], and [group4].
 
OR
 
[Disease name] may be classified into [large number > 6] subtypes based on [classification method 1], [classification method 2], and [classification method 3].
[Disease name] may be classified into several subtypes based on [classification method 1], [classification method 2], and [classification method 3].
 
OR
 
Based on the duration of symptoms, [disease name] may be classified as either acute or chronic.
 
OR
 
If the staging system involves specific and characteristic findings and features:
According to the [staging system + reference], there are [number] stages of [malignancy name] based on the [finding1], [finding2], and [finding3]. Each stage is assigned a [letter/number1] and a [letter/number2] that designate the [feature1] and [feature2].
 
OR
 
The staging of [malignancy name] is based on the [staging system].
 
OR
 
There is no established system for the staging of [malignancy name].


==Classification==
==Classification==
 
*Pleomorphic adenoma can be classified based on the [[stromal]] content of the [[tumor]] into the following subgroups.<ref name="pmid1002574">{{cite journal |vauthors=Seifert G, Langrock I, Donath K |title=[A pathological classification of pleomorphic adenoma of the salivary glands (author's transl)] |language=German |journal=HNO |volume=24 |issue=12 |pages=415–26 |date=December 1976 |pmid=1002574 |doi= |url=}}</ref>
There is no established system for the classification of [disease name].
**Subgroup 1 is the classical pleomorphic adenoma with a [[stroma]] content of 30-50%
 
**subgroup 2 has a [[stroma]] content of 80%
OR
**subgroup 3 has a poor [[stroma]] content of 20-30% or less and an [[epithelial]] [[differentiation]] similar to subgroup 1
 
**subgroup 4 has also a poor [[stroma]] content (6%) with a relatively monomorphic [[epithelial]] structure.
[Disease name] may be classified according to [classification method] into [number] subtypes/groups:
*Depending upon which component predominates pleomorphic adenoma can also be classified into:<ref name="ZhanKhaja2016">{{cite journal|last1=Zhan|first1=Kevin Y.|last2=Khaja|first2=Sobia F.|last3=Flack|first3=Allen B.|last4=Day|first4=Terry A.|title=Benign Parotid Tumors|journal=Otolaryngologic Clinics of North America|volume=49|issue=2|year=2016|pages=327–342|issn=00306665|doi=10.1016/j.otc.2015.10.005}}</ref>
*[Group1]
**[[Cellular]](either [[epithelial]] or [[myoepithelial cell]] rich)
*[Group2]
**[[Stroma]]-rich
*[Group3]
**Mixed type or classic
*[Group4]
 
OR
 
[Disease name] may be classified into [large number > 6] subtypes based on:
*[Classification method 1]
*[Classification method 2]
*[Classification method 3]
 
[Disease name] may be classified into several subtypes based on:  
*[Classification method 1]
*[Classification method 2]
*[Classification method 3]
 
OR
 
Based on the duration of symptoms, [disease name] may be classified as either acute or chronic.
 
OR
 
'''If the staging system involves specific and characteristic findings and features:'''
 
According to the [staging system + reference], there are [number] stages of [malignancy name] based on the [finding1], [finding2], and [finding3]. Each stage is assigned a [letter/number1] and a [letter/number2] that designate the [feature1] and [feature2].
 
OR
 
The staging of [malignancy name] is based on the [staging system].
 
OR
 
There is no established system for the staging of [malignancy name].


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
{{WH}}
{{WH}}
{{WS}}
{{WS}}
[[Category: (name of the system)]]
 
[[Category: Otolaryngology]]
[[Category: Medicine]]
[[Category: Oncology]]
[[Category: Surgery]]
[[Category: Up-To-Date]]

Latest revision as of 18:42, 28 January 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Maneesha Nandimandalam, M.B.B.S.[2]

Overview

Pleomorphic adenoma can be classified into 4 subgroups on the basis of histology appearance and stromal content into 4 groups. Subgroup 1, subgroup 2, subgroup 3, subgroup 4. It can also be classified based upon the component that predominates into 3 types, cellular, stroma rich, and mixed type.

Classification

  • Pleomorphic adenoma can be classified based on the stromal content of the tumor into the following subgroups.[1]
    • Subgroup 1 is the classical pleomorphic adenoma with a stroma content of 30-50%
    • subgroup 2 has a stroma content of 80%
    • subgroup 3 has a poor stroma content of 20-30% or less and an epithelial differentiation similar to subgroup 1
    • subgroup 4 has also a poor stroma content (6%) with a relatively monomorphic epithelial structure.
  • Depending upon which component predominates pleomorphic adenoma can also be classified into:[2]

References

  1. ↑ Seifert G, Langrock I, Donath K (December 1976). "[A pathological classification of pleomorphic adenoma of the salivary glands (author's transl)]". HNO (in German). 24 (12): 415–26. PMID 1002574.
  2. ↑ Zhan, Kevin Y.; Khaja, Sobia F.; Flack, Allen B.; Day, Terry A. (2016). "Benign Parotid Tumors". Otolaryngologic Clinics of North America. 49 (2): 327–342. doi:10.1016/j.otc.2015.10.005. ISSN 0030-6665.

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