Pleomorphic adenoma classification: Difference between revisions
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{{Pleomorphic adenoma}} | {{Pleomorphic adenoma}} | ||
{{CMG}}; {{AE}} | {{CMG}}; {{AE}} {{M.N}} | ||
==Overview== | ==Overview== | ||
Pleomorphic adenoma can be classified into 4 subgroups on the basis of | Pleomorphic adenoma can be classified into 4 subgroups on the basis of [[histology]] appearance and [[stromal]] content into 4 groups. Subgroup 1, subgroup 2, subgroup 3, subgroup 4. It can also be classified based upon the component that predominates into 3 types, [[cellular]], [[stroma]] rich, and mixed type. | ||
==Classification== | ==Classification== | ||
*Pleomorphic adenoma can be classified based on the stromal content of the tumor into the following subgroups.<ref name="pmid1002574">{{cite journal |vauthors=Seifert G, Langrock I, Donath K |title=[A pathological classification of pleomorphic adenoma of the salivary glands (author's transl)] |language=German |journal=HNO |volume=24 |issue=12 |pages=415–26 |date=December 1976 |pmid=1002574 |doi= |url=}}</ref> | *Pleomorphic adenoma can be classified based on the [[stromal]] content of the [[tumor]] into the following subgroups.<ref name="pmid1002574">{{cite journal |vauthors=Seifert G, Langrock I, Donath K |title=[A pathological classification of pleomorphic adenoma of the salivary glands (author's transl)] |language=German |journal=HNO |volume=24 |issue=12 |pages=415–26 |date=December 1976 |pmid=1002574 |doi= |url=}}</ref> | ||
**Subgroup 1 is the classical pleomorphic adenoma with a stroma content of 30-50% | **Subgroup 1 is the classical pleomorphic adenoma with a [[stroma]] content of 30-50% | ||
**subgroup 2 has a stroma content of 80% | **subgroup 2 has a [[stroma]] content of 80% | ||
**subgroup 3 has a poor stroma content of 20-30% or less and an epithelial differentiation similar to subgroup 1 | **subgroup 3 has a poor [[stroma]] content of 20-30% or less and an [[epithelial]] [[differentiation]] similar to subgroup 1 | ||
**subgroup 4 has also a poor stroma content (6%) with a relatively monomorphic epithelial structure. | **subgroup 4 has also a poor [[stroma]] content (6%) with a relatively monomorphic [[epithelial]] structure. | ||
*Depending upon which component predominates pleomorphic adenoma can also be classified into:<ref name="ZhanKhaja2016">{{cite journal|last1=Zhan|first1=Kevin Y.|last2=Khaja|first2=Sobia F.|last3=Flack|first3=Allen B.|last4=Day|first4=Terry A.|title=Benign Parotid Tumors|journal=Otolaryngologic Clinics of North America|volume=49|issue=2|year=2016|pages=327–342|issn=00306665|doi=10.1016/j.otc.2015.10.005}}</ref> | *Depending upon which component predominates pleomorphic adenoma can also be classified into:<ref name="ZhanKhaja2016">{{cite journal|last1=Zhan|first1=Kevin Y.|last2=Khaja|first2=Sobia F.|last3=Flack|first3=Allen B.|last4=Day|first4=Terry A.|title=Benign Parotid Tumors|journal=Otolaryngologic Clinics of North America|volume=49|issue=2|year=2016|pages=327–342|issn=00306665|doi=10.1016/j.otc.2015.10.005}}</ref> | ||
**Cellular(either epithelial or myoepithelial cell rich) | **[[Cellular]](either [[epithelial]] or [[myoepithelial cell]] rich) | ||
**Stroma-rich | **[[Stroma]]-rich | ||
**Mixed type or classic | **Mixed type or classic | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category: | |||
[[Category: Otolaryngology]] | |||
[[Category: Medicine]] | |||
[[Category: Oncology]] | |||
[[Category: Surgery]] | |||
[[Category: Up-To-Date]] | |||
Latest revision as of 18:42, 28 January 2019
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Risk calculators and risk factors for Pleomorphic adenoma classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Maneesha Nandimandalam, M.B.B.S.[2]
Overview
Pleomorphic adenoma can be classified into 4 subgroups on the basis of histology appearance and stromal content into 4 groups. Subgroup 1, subgroup 2, subgroup 3, subgroup 4. It can also be classified based upon the component that predominates into 3 types, cellular, stroma rich, and mixed type.
Classification
- Pleomorphic adenoma can be classified based on the stromal content of the tumor into the following subgroups.[1]
- Subgroup 1 is the classical pleomorphic adenoma with a stroma content of 30-50%
- subgroup 2 has a stroma content of 80%
- subgroup 3 has a poor stroma content of 20-30% or less and an epithelial differentiation similar to subgroup 1
- subgroup 4 has also a poor stroma content (6%) with a relatively monomorphic epithelial structure.
- Depending upon which component predominates pleomorphic adenoma can also be classified into:[2]
- Cellular(either epithelial or myoepithelial cell rich)
- Stroma-rich
- Mixed type or classic
References
- ↑ Seifert G, Langrock I, Donath K (December 1976). "[A pathological classification of pleomorphic adenoma of the salivary glands (author's transl)]". HNO (in German). 24 (12): 415–26. PMID 1002574.
- ↑ Zhan, Kevin Y.; Khaja, Sobia F.; Flack, Allen B.; Day, Terry A. (2016). "Benign Parotid Tumors". Otolaryngologic Clinics of North America. 49 (2): 327–342. doi:10.1016/j.otc.2015.10.005. ISSN 0030-6665.