Chronic neutrophilic leukemia other diagnostic studies: Difference between revisions
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{{Chronic neutrophilic leukemia}} | {{Chronic neutrophilic leukemia}} | ||
{{CMG}}; {{AE}} | {{CMG}}; {{AE}} {{Homa}}; {{GRR}} {{Nat}} | ||
==Overview== | ==Overview== | ||
Bone marrow morphology may be helpful in the diagnosis of chronic neutrophilic leukemia (CNL). Hypercellularity with [[myeloid]] [[hyperplasia]], increasing [[myeloid]] to [[erythroid]] ratio, increasing of [[myelocyte]]<nowiki/>s, [[metamyelocyte]]<nowiki/>s, and [[bands]], absence of [[basophilia]] and [[eosinophilia]],Megakaryocytic [[hyperplasia]] | |||
==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
===Bone marrow | ===Bone marrow biopsy=== | ||
*Bone marrow study may be helpful in the diagnosis of CNL. | *[[Bone marrow]] study may be helpful in the [[diagnosis]] of CNL. | ||
*Findings suggestive of | *Findings suggestive of CNL include:<ref name="UppalGong2015">{{cite journal|last1=Uppal|first1=Guldeep|last2=Gong|first2=Jerald|title=Chronic neutrophilic leukaemia|journal=Journal of Clinical Pathology|volume=68|issue=9|year=2015|pages=680–684|issn=0021-9746|doi=10.1136/jclinpath-2015-203060}}</ref><ref>{{cite book | last = Swerdlow | first = Steven | title = WHO classification of tumours of haematopoietic and lymphoid tissues | publisher = International Agency for Research on Cancer | location = Lyon, France | year = 2008 | isbn = 9789283224310 }}</ref> | ||
**Hypercellularity with myeloid hyperplasia | **Hypercellularity with [[myeloid]] [[hyperplasia]] | ||
**Increasing myeloid to erythroid ratio | **Increasing [[myeloid]] to [[erythroid]] ratio | ||
**Increasing of | **Increasing of [[myelocyte]]<nowiki/>s, [[metamyelocyte]]<nowiki/>s, and [[bands]] | ||
**Absence of basophilia and eosinophilia | **Absence of [[basophilia]] and [[eosinophilia]] | ||
**Megakaryocytic hyperplasia | **Megakaryocytic [[hyperplasia]] | ||
==References== | ==References== | ||
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{{WS}} | {{WS}} | ||
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[[Category:Oncology]] | |||
[[Category:Hematology]] | |||
[[Category:Immunology]] | |||
Latest revision as of 20:58, 29 July 2020
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Chronic neutrophilic leukemia Microchapters |
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Differentiating Chronic neutrophilic leukemia from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Homa Najafi, M.D.[2]; Grammar Reviewer: Natalie Harpenau, B.S.[3]
Overview
Bone marrow morphology may be helpful in the diagnosis of chronic neutrophilic leukemia (CNL). Hypercellularity with myeloid hyperplasia, increasing myeloid to erythroid ratio, increasing of myelocytes, metamyelocytes, and bands, absence of basophilia and eosinophilia,Megakaryocytic hyperplasia
Other Diagnostic Studies
Bone marrow biopsy
- Bone marrow study may be helpful in the diagnosis of CNL.
- Findings suggestive of CNL include:[1][2]
- Hypercellularity with myeloid hyperplasia
- Increasing myeloid to erythroid ratio
- Increasing of myelocytes, metamyelocytes, and bands
- Absence of basophilia and eosinophilia
- Megakaryocytic hyperplasia
References
- ↑ Uppal, Guldeep; Gong, Jerald (2015). "Chronic neutrophilic leukaemia". Journal of Clinical Pathology. 68 (9): 680–684. doi:10.1136/jclinpath-2015-203060. ISSN 0021-9746.
- ↑ Swerdlow, Steven (2008). WHO classification of tumours of haematopoietic and lymphoid tissues. Lyon, France: International Agency for Research on Cancer. ISBN 9789283224310.