Sandbox gc

Definition of Multivessel Disease

For AEGIS-II inclusion criteria #5, multivessel disease criteria can be met by findings on the cardiac catheterization for the index MI, a prior cardiac catheterization, or both:

• Index MI cardiac catheterization: 50% or greater stenosis of the left main or at least 2 coronary artery territories (LAD, LCX, RCA) (prior to any interventions performed)
• Prior cardiac catheterization: 50% or greater stenosis of left main or at least 2 coronary artery territories (LAD, LCx, RCA) (prior to any interventions performed)
• Both: Index MI cardiac catheterization with 1 vessel with 50% or greater stenosis (prior to any interventions performed) AND prior PCI of at least 1 vessel different from index MI vessel
• Prior multivessel CABG

Multivessel disease requires a 50% or greater stenosis in at least 2 of the 3 major epicardial artery territories (LAD, LCx, RCA) or the left main vessel. Branch vessel disease may qualify as part of the territory of that branch vessel (for example, a diagonal vessel is considered part of the LAD territory). For the purpose of this study, the ramus is considered part of the Left Circumflex artery territory. If a branch vessel is used as a qualifying vessel, that branch should be of large enough size to potentially undergo revascularization if clinically indicated, e.g. >2mm vessel size.

MVD Tool

Multivessel Disease Tool
To determine if your patient meets the eligibility criteria for multivessel disease, please check all arteries/segments with 50% or greater stenosis on the cardiac catheterization for index MI and/or vessels that have received prior PCI (stent or balloon angioplasty).
Left Main Coronary Artery	Left Main Artery
Left Anterior Descending Artery	Proximal LAD
	Middle LAD
	Distal LAD
	First Diagonal Artery
	Second Diagonal Artery
	Third Diagonal Artery
Circumflex Artery	Proximal Cx
	Middle Cx
	Distal Cx
	First Obtuse Marginal Artery
	Second Obtuse Marginal Artery
	Third Obtuse Marginal Artery
	Left Posterior Descending Artery
	Left Posterior Atrioventricular Artery
	Left Posterolateral Artery
	Ramus Intermedius Artery
Right Coronary Artery	Proximal RCA
	Middle RCA
	Distal RCA
	Right Posterior Descending Artery
	Right Posterior Atrioventricular Artery
	Right Posterolateral Artery
Prior Multivessel Coronary Artery Bypass Grafting
Interpretation: