Lymphoplasmacytic lymphoma classification: Difference between revisions
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{{CMG}}; {{AE}}{{S.M.}} | {{CMG}}; {{AE}}{{S.M.}} | ||
==Overview== | ==Overview== | ||
There is no established system for the classification of lymphoplasmacytic lymphoma. However, according to a devised criteria based upon patient's symptoms, Waldenström's macroglobulinemia can be further classified into smoldering/asymptomatic and symptomatic WM . | There is no established [[system]] for the [[classification]] of [[lymphoplasmacytic lymphoma]]. However, according to a devised [[criteria]] [[Based on Symptoms|based upon patient's symptoms]], [[Waldenström's macroglobulinemia]] can be further [[Classification|classified]] into smoldering/[[asymptomatic]] and [[symptomatic]] [[Waldenstrom macroglobulinemia]]([[Waldenström's macroglobulinemia|WM)]]. | ||
==Classification== | ==Classification== | ||
There is no established system for the classification of | There is no established [[system]] for the [[classification]] of [[lymphoplasmacytic lymphoma]]. However, according to a devised [[criteria]] [[Based on Symptoms|based upon patient's symptoms]], [[Waldenström's macroglobulinemia]] can be further [[Classification|classified]] into:<ref name="pmid15735132">{{cite journal| author=Dimopoulos MA, Kyle RA, Anagnostopoulos A, Treon SP| title=Diagnosis and management of Waldenstrom's macroglobulinemia. | journal=J Clin Oncol | year= 2005 | volume= 23 | issue= 7 | pages= 1564-77 | pmid=15735132 | doi=10.1200/JCO.2005.03.144 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15735132 }} </ref> | ||
*Symptomatic Waldenstrom macroglobulinemia | |||
*Asymptomatic/Smoldering Waldenstrom macroglobulinemia (SWM) | *[[Symptomatic]] [[Waldenstrom macroglobulinemia]] | ||
{| | *[[Asymptomatic]]/Smoldering [[Waldenstrom macroglobulinemia]] (SWM)<ref name="pmid12720119">{{cite journal| author=Kyle RA, Treon SP, Alexanian R, Barlogie B, Björkholm M, Dhodapkar M et al.| title=Prognostic markers and criteria to initiate therapy in Waldenstrom's macroglobulinemia: consensus panel recommendations from the Second International Workshop on Waldenstrom's Macroglobulinemia. | journal=Semin Oncol | year= 2003 | volume= 30 | issue= 2 | pages= 116-20 | pmid=12720119 | doi=10.1053/sonc.2003.50038 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12720119 }} </ref> | ||
|+ '''Classification of WM and Related Disorders''' | |||
{| | |||
|+'''Classification of [[Waldenstrom macroglobulinemia]] (WM) and Related Disorders''' | |||
! style="background:#4479BA; color: #FFFFFF;" align="center" + |Criteria | ! style="background:#4479BA; color: #FFFFFF;" align="center" + |Criteria | ||
! style="background:#4479BA; color: #FFFFFF;" align="center" + |Symptomatic WM | ! style="background:#4479BA; color: #FFFFFF;" align="center" + |Symptomatic WM | ||
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! style="background:#4479BA; color: #FFFFFF;" align="center" + |MGUS | ! style="background:#4479BA; color: #FFFFFF;" align="center" + |MGUS | ||
|- | |- | ||
! align="center" style="background:#DCDCDC;" + |[[IgM monoclonal protein]] | |||
| style="background:#F5F5F5;" align="center" + |+ | | style="background:#F5F5F5;" align="center" + | + | ||
| style="background:#F5F5F5;" align="center" + |+ | | style="background:#F5F5F5;" align="center" + | + | ||
| style="background:#F5F5F5;" align="center" + |+ | | style="background:#F5F5F5;" align="center" + | + | ||
| style="background:#F5F5F5;" align="center" + |+ | | style="background:#F5F5F5;" align="center" + | + | ||
|- | |- | ||
! align="center" style="background:#DCDCDC;" + |Bone marrow infiltration | |||
| style="background:#F5F5F5;" align="center" + |+ | | style="background:#F5F5F5;" align="center" + | + | ||
| style="background:#F5F5F5;" align="center" + |+ | | style="background:#F5F5F5;" align="center" + | + | ||
| style="background:#F5F5F5;" align="center" + |- | | style="background:#F5F5F5;" align="center" + | - | ||
| style="background:#F5F5F5;" align="center" + |- | | style="background:#F5F5F5;" align="center" + | - | ||
|- | |- | ||
! align="center" style="background:#DCDCDC;" + |Symptoms attributable to IgM | |||
| style="background:#F5F5F5;" align="center" + |+ | | style="background:#F5F5F5;" align="center" + | + | ||
| style="background:#F5F5F5;" align="center" + |- | | style="background:#F5F5F5;" align="center" + | - | ||
| style="background:#F5F5F5;" align="center" + |+ | | style="background:#F5F5F5;" align="center" + | + | ||
| style="background:#F5F5F5;" align="center" + |- | | style="background:#F5F5F5;" align="center" + | - | ||
|- | |- | ||
! align="center" style="background:#DCDCDC;" + |Symptoms attributable to tumor infiltration | |||
| style="background:#F5F5F5;" align="center" + |+ | | style="background:#F5F5F5;" align="center" + | + | ||
| style="background:#F5F5F5;" align="center" + |- | | style="background:#F5F5F5;" align="center" + | - | ||
| style="background:#F5F5F5;" align="center" + |- | | style="background:#F5F5F5;" align="center" + | - | ||
| style="background:#F5F5F5;" align="center" + |- | | style="background:#F5F5F5;" align="center" + | - | ||
|} | |}<br /> | ||
==References== | ==References== | ||
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{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category: | [[Category:Disease]] | ||
[[Category:Blood]] | |||
[[Category:Hematology]] | |||
Latest revision as of 17:26, 8 April 2021
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Lymphoplasmacytic lymphoma Microchapters |
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Differentiating Lymphoplasmacytic Lymphoma from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Lymphoplasmacytic lymphoma classification On the Web |
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American Roentgen Ray Society Images of Lymphoplasmacytic lymphoma classification |
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Risk calculators and risk factors for Lymphoplasmacytic lymphoma classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2]
Overview
There is no established system for the classification of lymphoplasmacytic lymphoma. However, according to a devised criteria based upon patient's symptoms, Waldenström's macroglobulinemia can be further classified into smoldering/asymptomatic and symptomatic Waldenstrom macroglobulinemia(WM).
Classification
There is no established system for the classification of lymphoplasmacytic lymphoma. However, according to a devised criteria based upon patient's symptoms, Waldenström's macroglobulinemia can be further classified into:[1]
- Symptomatic Waldenstrom macroglobulinemia
- Asymptomatic/Smoldering Waldenstrom macroglobulinemia (SWM)[2]
| Criteria | Symptomatic WM | Asymptomatic WM | IgM-Related Disorders | MGUS |
|---|---|---|---|---|
| IgM monoclonal protein | + | + | + | + |
| Bone marrow infiltration | + | + | - | - |
| Symptoms attributable to IgM | + | - | + | - |
| Symptoms attributable to tumor infiltration | + | - | - | - |
References
- ↑ Dimopoulos MA, Kyle RA, Anagnostopoulos A, Treon SP (2005). "Diagnosis and management of Waldenstrom's macroglobulinemia". J Clin Oncol. 23 (7): 1564–77. doi:10.1200/JCO.2005.03.144. PMID 15735132.
- ↑ Kyle RA, Treon SP, Alexanian R, Barlogie B, Björkholm M, Dhodapkar M; et al. (2003). "Prognostic markers and criteria to initiate therapy in Waldenstrom's macroglobulinemia: consensus panel recommendations from the Second International Workshop on Waldenstrom's Macroglobulinemia". Semin Oncol. 30 (2): 116–20. doi:10.1053/sonc.2003.50038. PMID 12720119.