Gonadoblastoma screening: Difference between revisions
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{{CMG}}; {{AE}} {{Sahar}} | {{CMG}}; {{AE}} {{Sahar}} | ||
==Overview== | ==Overview== | ||
There is insufficient [[evidence]] to recommend routine [[screening]] for gonadoblastoma. However, patients with XY [[gonadal]] abnormalities should be followed using [[sonography]] starting at age 2, every six months, until the gonads are removed. | There is insufficient [[evidence]] to recommend routine [[screening]] for gonadoblastoma. However, patients with XY [[gonadal]] [[abnormalities]] should be followed using [[sonography]] starting at [[age]] 2, every six months, until the [[gonads]] are removed. | ||
==Screening== | ==Screening== | ||
*There is insufficient [[evidence]] to recommend routine [[screening]] for gonadoblastoma. | *There is insufficient [[evidence]] to recommend routine [[screening]] for gonadoblastoma. | ||
*However, patients with XY [[gonadal]] abnormalities should be followed using [[sonography]] starting at age 2, every six months, until the gonads are removed.<ref name="urlYen & Jaffes Reproductive Endocrinology | ScienceDirect">{{cite web |url=https://www.sciencedirect.com/book/9781455727582/yen-and-jaffes-reproductive-endocrinology |title=Yen & Jaffe's Reproductive Endocrinology | ScienceDirect |format= |work= |accessdate=}}</ref><ref name="pmid10226831">{{cite journal |vauthors=Hatano T, Yoshino Y, Kawashima Y, Shirai H, Iizuka N, Miyazawa Y, Sakata A, Onishi T |title=Case of gonadoblastoma in a 9-year-old boy without physical abnormalities |journal=Int. J. Urol. |volume=6 |issue=3 |pages=164–6 |date=March 1999 |pmid=10226831 |doi= |url=}}</ref> | *However, patients with XY [[gonadal]] [[abnormalities]] should be followed using [[sonography]] starting at [[age]] 2, every six months, until the [[gonads]] are removed.<ref name="urlYen & Jaffes Reproductive Endocrinology | ScienceDirect">{{cite web |url=https://www.sciencedirect.com/book/9781455727582/yen-and-jaffes-reproductive-endocrinology |title=Yen & Jaffe's Reproductive Endocrinology | ScienceDirect |format= |work= |accessdate=}}</ref><ref name="pmid10226831">{{cite journal |vauthors=Hatano T, Yoshino Y, Kawashima Y, Shirai H, Iizuka N, Miyazawa Y, Sakata A, Onishi T |title=Case of gonadoblastoma in a 9-year-old boy without physical abnormalities |journal=Int. J. Urol. |volume=6 |issue=3 |pages=164–6 |date=March 1999 |pmid=10226831 |doi= |url=}}</ref> | ||
*Although very uncommon, gonadoblastoma may develop in phenotypically and genotypically normal individuals. | *Although very uncommon, gonadoblastoma may develop in [[Phenotype|phenotypically]] and [[Genotype|genotypically]] normal individuals. | ||
**In these individuals, the affected [[gonad|go]]<nowiki/>[[gonad|nad]]<nowiki/>s must be removed due to the risk of gonadoblastoma conversion to [[dysgerminoma]]. | **In these individuals, the affected [[gonad|go]]<nowiki/>[[gonad|nad]]<nowiki/>s must be removed due to the risk of gonadoblastoma conversion to [[dysgerminoma]]. | ||
**Close monitoring with [[imaging studies|im]]<nowiki/>[[imaging studies|aging studies]] also recommended for the [[contralateral]]<nowiki/> [[gonad]]<nowiki/>s if it is preserved. | **Close monitoring with [[imaging studies|im]]<nowiki/>[[imaging studies|aging studies]] also recommended for the [[contralateral]]<nowiki/> [[gonad]]<nowiki/>s if it is preserved. | ||
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== References == | == References == | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Medicine]] | |||
[[Category:Oncology]] | |||
[[Category:Gynecology]] | |||
[[Category:Up-To-Date]] | |||
Latest revision as of 21:54, 29 July 2020
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Gonadoblastoma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Gonadoblastoma screening On the Web |
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American Roentgen Ray Society Images of Gonadoblastoma screening |
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Risk calculators and risk factors for Gonadoblastoma screening |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]
Overview
There is insufficient evidence to recommend routine screening for gonadoblastoma. However, patients with XY gonadal abnormalities should be followed using sonography starting at age 2, every six months, until the gonads are removed.
Screening
- There is insufficient evidence to recommend routine screening for gonadoblastoma.
- However, patients with XY gonadal abnormalities should be followed using sonography starting at age 2, every six months, until the gonads are removed.[1][2]
- Although very uncommon, gonadoblastoma may develop in phenotypically and genotypically normal individuals.
- In these individuals, the affected gonads must be removed due to the risk of gonadoblastoma conversion to dysgerminoma.
- Close monitoring with imaging studies also recommended for the contralateral gonads if it is preserved.
References
- ↑ "Yen & Jaffe's Reproductive Endocrinology | ScienceDirect".
- ↑ Hatano T, Yoshino Y, Kawashima Y, Shirai H, Iizuka N, Miyazawa Y, Sakata A, Onishi T (March 1999). "Case of gonadoblastoma in a 9-year-old boy without physical abnormalities". Int. J. Urol. 6 (3): 164–6. PMID 10226831.