Appendix cancer history and symptoms: Difference between revisions
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{{CMG}}; {{AE}} {{Soroush}} | {{CMG}}; {{AE}} {{Soroush}} | ||
==Overview== | ==Overview== | ||
The majority of patients with appendix cancer are [[asymptomatic]]. Patients may | The majority of patients with appendix cancer are [[asymptomatic]]. Patients may complain of vague [[abdominal pain]] or discomfort and/or girdle size changes. However, most of them are presenting with [[Appendicitis|acute appendicitis]] due to obstruction of the [[Vermiform appendix|appendix]] by [[tumor]], or present with [[Cancer|malignancy]] [[Complication (medicine)|complications]] like [[pseudomyxoma peritonei]]; the rest of diagnosed cases are result of serendipitous finding in i[[Imaging studies|maging studies]] or discovered during [[laparotomy]] or [[Laparoscopic surgery|laparoscopy]] because of cancer complications. The patients complains and presentation is influenced by the [[tumor]] [[histology]] and stage and ranges from a small [[asymptomatic]] [[adenocarcinoma]] to a [[Metastasis|metastatic]] [[Carcinoid Tumor|carcinoid]] tumor with liver metastasis and [[carcinoid syndrome]] signs, symptoms and [[Complication (medicine)|complications]]. | ||
==History and Symptoms== | ==History and Symptoms== | ||
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===Common Symptoms=== | ===Common Symptoms=== | ||
* Common symptoms of appendix cancer are as follows: | * Common symptoms of appendix cancer are as follows: | ||
** | **Asymptomatic | ||
**Vague | **Vague chronic [[abdominal pain]] | ||
*** Periumbilical | *** Periumbilical | ||
***Right lower quadrant | ***Right lower quadrant | ||
**[[Appendicitis|Acute appendicitis]] symptoms like: | **[[Appendicitis|Acute appendicitis]] symptoms like: | ||
*** | ***Loss of [[appetite]] | ||
***[[Nausea and vomiting|Nausea]] | ***[[Nausea and vomiting|Nausea]] | ||
***Typical [[appendicitis]] [[abdominal pain]] which [[Appendicitis diagnostic scoring|starts from preumblical region and move to Mcburny point]]. | ***Typical [[appendicitis]] [[abdominal pain]] which [[Appendicitis diagnostic scoring|starts from preumblical region and move to Mcburny point]]. | ||
***[[Nausea and vomiting|Vomiting]] | ***[[Nausea and vomiting|Vomiting]] | ||
* '''''If complicated may present with acute abdomen.''''' | * '''''If complicated, may present with acute abdomen.''''' | ||
* | * | ||
* Other nonspecific symptoms of appendix cancer may include the following: <ref>Hardin, M. Acute Appendicitis: Review and Update. ''Am Fam Physician".1999, Nov 1;60(7):2027-2034''</ref> | * Other nonspecific symptoms of appendix cancer may include the following:<ref>Hardin, M. Acute Appendicitis: Review and Update. ''Am Fam Physician".1999, Nov 1;60(7):2027-2034''</ref> | ||
:* [[Loss of appetite]] | :* [[Loss of appetite]] | ||
:* [[Nausea]] | :* [[Nausea]] | ||
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{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category: | [[Category:Surgery]] | ||
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[[Category:Oncology]] | |||
[[Category:Up-To-Date]] |
Latest revision as of 17:50, 22 February 2019
Appendix cancer Microchapters |
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Appendix cancer history and symptoms On the Web |
American Roentgen Ray Society Images of Appendix cancer history and symptoms |
Risk calculators and risk factors for Appendix cancer history and symptoms |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Soroush Seifirad, M.D.[2]
Overview
The majority of patients with appendix cancer are asymptomatic. Patients may complain of vague abdominal pain or discomfort and/or girdle size changes. However, most of them are presenting with acute appendicitis due to obstruction of the appendix by tumor, or present with malignancy complications like pseudomyxoma peritonei; the rest of diagnosed cases are result of serendipitous finding in imaging studies or discovered during laparotomy or laparoscopy because of cancer complications. The patients complains and presentation is influenced by the tumor histology and stage and ranges from a small asymptomatic adenocarcinoma to a metastatic carcinoid tumor with liver metastasis and carcinoid syndrome signs, symptoms and complications.
History and Symptoms
- The majority of patients with appendix cancer are asymptomatic.
- Patients may complaint of vague abdominal pain or discomfort and/or girdle size changes.
- However, most of them are presenting with acute appendicitis due to obstruction of the appendix by the tumor, only after pathological studies their diagnosis is revealed.[1]
- They may present with malignancy complications like pseudomyxoma peritonei.
- Rest of the diagnosed cases are result of serendipitous finding in imaging studies or discovered during laparotomy or laparoscopy because of cancer complications.
- The patients complaints and presentation is influenced by the tumor histology and stage. Range from a small asymptomatic adenocarcinoma to a metastatic carcinoid tumor with liver metastasis and carcinoid syndrome signs, symptoms and complications such as diarrhea, flushing, palpitation and heart valvular problems. [2]
History
Patients with appendix cancer may have a positive history of:[2]
Common Symptoms
- Common symptoms of appendix cancer are as follows:
- Asymptomatic
- Vague chronic abdominal pain
- Periumbilical
- Right lower quadrant
- Acute appendicitis symptoms like:
- Loss of appetite
- Nausea
- Typical appendicitis abdominal pain which starts from preumblical region and move to Mcburny point.
- Vomiting
- If complicated, may present with acute abdomen.
- Other nonspecific symptoms of appendix cancer may include the following:[3]
- Loss of appetite
- Nausea
- Vomiting
- Diarrhea
- Micturition
- Tenesmus
- Indigestion
- Flatulence
- Bowel irregularity
Less Common Symptoms
Around 5% of the patients with appendix carcinoid tumors develop carcinoid syndrome which presents with: [4]
References
- ↑ Kelly KJ (2015) Management of Appendix Cancer. Clin Colon Rectal Surg 28 (4):247-55. DOI:10.1055/s-0035-1564433 PMID: 26648795
- ↑ 2.0 2.1 Chapter 5: Tumours of the Appendix - IARC. https://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb2/bb2-chap5.pdf Accessed on January 15, 2019
- ↑ Hardin, M. Acute Appendicitis: Review and Update. Am Fam Physician".1999, Nov 1;60(7):2027-2034
- ↑ Signs and symptoms of carcinoid syndrome. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/patient/gi-carcinoid-treatment-pdq