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| __NOTOC__
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| {{Desmoid tumor}}
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| {{CMG}} {{AE}}{{S.M.}}
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| ==Overview==
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| Antibodies including smooth muscle actin, desmin and KIT are often examined to aid in distinguishing desmoids from other tumors.
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| ==Other diagnostic studies==
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| {| class="wikitable"
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| |+Characteristic features of desmoid tumors on immunohistochemistry and relevant antibodies
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| !Other diagnostic tests
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| !Associated characteristics features
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| |-
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| |Immunohistochemistry
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| (aids histologic diagnosis)
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| |Spindle cells on immunohistochemical stains show the following features:
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| *Positive for:
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| **Nuclear beta-catenin (regardless of the site, 90% of desmoids show nuclear reactivity, relatively high specificity)
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| **Vimentin
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| **Smooth muscle actin
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| *Negative for:
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| **Desmin
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| **Cytokeratins
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| **S-100
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| |-
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| |Antibodies
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| |In order to distinguish desmoid tumors from other tumors, following antibodies are often examined:
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| *Smooth muscle actin
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| *Desmin
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| *KIT
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| |}
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| ==Reference==
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| {{Reflist|2}}
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| {{WikiDoc Help Menu}}
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| {{WikiDoc Sources}}
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| [[Category:Disease]]
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| [[Category:Up-To-Date]]
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| [[Category:Oncology]]
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| [[Category:Medicine]]
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