|
|
(5 intermediate revisions by the same user not shown) |
Line 1: |
Line 1: |
| __NOTOC__
| |
| {{Thyroid adenoma}}
| |
| {{CMG}}; {{AE}} {{Ammu}}
| |
| ==Overview==
| |
|
| |
|
| [[Needle aspiration biopsy|Fine needle aspiration biopsy]] may be helpful in the [[diagnosis]] of thyroid adenoma. Findings on fine needle aspiration biopsy suggestive of thyroid adenoma include cystic changes, [[fibrosis]], and areas of [[hemorrhage]].
| |
|
| |
| ==Biopsy==
| |
| * One approach used to determine the type of adenoma is fine needle biopsy (FNB), which some have described as the most cost-effective, sensitive, and accurate test.<ref>
| |
| {{cite journal
| |
| | last = Hamberger
| |
| | first = B
| |
| | year = 1982
| |
| | title = Fine-needle aspiration biopsy of thyroid nodules. Impact on thyroid practice and cost of care
| |
| | journal = Am J Med
| |
| | volume = 73
| |
| | pages = 381–384
| |
| | pmid = 7124765
| |
| | doi=10.1016/0002-9343(82)90731-8
| |
| | issue=3
| |
| }}
| |
| </ref><ref>
| |
| {{cite journal
| |
| | last = Mazzaferri
| |
| | year = 1993
| |
| | title = Management of a Solitary Thyroid Nodule
| |
| | journal = N Engl J Med
| |
| | volume = 328
| |
| | pages = 553–9
| |
| | pmid = 8426623
| |
| | doi=10.1056/NEJM199302253280807
| |
| | issue=8
| |
| }}
| |
| </ref>
| |
| * [[Needle aspiration biopsy|Fine needle aspiration biopsy]] or ultrasound-guided [[Needle aspiration biopsy|fine needle aspiration biopsy]] usually yields sufficient thyroid cells to assess the [[pathology]], although in some cases, the suspected nodule may need to be removed surgically for pathological examination.
| |
| ===Key Biopsy Findings in Thyroid adenoma===
| |
| * Areas of [[hemorrhage]], [[fibrosis]], [[calcification]], and cystic change are common in thyroid (follicular) adenoma, particularly in larger lesions.
| |
| * Encapsulated [[tumor]]s do not have any evidence of infiltration.
| |
| * Colloid nodules are distinguished by an apparently gelatinous mass of [[colloid]] both surrounding and contained within [[follicular cell]]s. Colloid nodules are not surrounded by a [[fibrous capsule]] of compressed tissue. However, they are surrounded by flattened [[epithelium|epithelial]] cells.<ref>{{cite web |url=http://rcpa.tv/parts/educational/anatomical/Dr_Alpha_Tsui/Thyroid_cytology.pdf |title=Thyroid cytology |author=Dr. Alpha Tsui |date=10 October 2010 |publisher=thyroidmanager.org |accessdate=26 September 2011}}</ref> Both the number of cells and the type of colloid may vary considerably.<ref>{{cite web |url=http://www.thyroidmanager.org/chapter%206d/fnabiopsy-frame.htm |title=Fine-Needle Aspiration Biopsy of the Thyroid Gland, Chapter 6d. |author=Diana S. Dean, M.D. Hossein Gharib, M.D. |date=10 October 2010 |publisher=thyroidmanager.org |accessdate=26 September 2011}}</ref>
| |
|
| |
|
| |
| {{Familytree/start}}
| |
| {{Familytree|boxstyle=background: #E0FFFF;| | | | | | | | | | | | | | A01 | | | | | | | | | | | | | | | | | | |A01= A patient with thyroid nodule}}
| |
| {{Familytree|boxstyle=background: #E0FFFF;| | | | | | | | | |,|-|-|-|-|^|-|-|-|-|.| | | | | | | | | | | | | | | | | | |}}
| |
| {{Familytree|boxstyle=background: #E0FFFF;| | | | | | | | | B01 | | | | | | | | B02 | | | | | | | | | | | | | | | |B01= Normal [[thyroid stimulating hormone]]|B02= Low [[thyroid stimulating hormone]]|}}
| |
| {{Familytree|boxstyle=background: #E0FFFF;| | | | | | |,|-|-|^|-|.| | | | | | | |!| | | | | | | | | | | | | | |}}
| |
| {{Familytree|boxstyle=background: #E0FFFF;| | | | | | C01 | | | C02 | | | | | | C03 | | | | | | | | | | | | | | | | | |C01= <1cm suspicious nodule|C02= >1cm nodule|C03=Thyroid nuclear scan}}
| |
| {{Familytree|boxstyle=background: #E0FFFF;| | | | | | |!| | | | |!| | | | |,|-|-|^|-|-|-|.| | | | | | | | | | | | | | | | | | | |}}
| |
| {{Familytree|boxstyle=background: #E0FFFF;| | | | | | D01 | | | D02 | | | | D03 | | | | D04 | | | | | | | | | | | | | | |D01= Ultrasound guided fine needle aspiration cytology|D02= Fine needle aspiration cytology|D03= Hot nodule|D04= Cold nodule}}{{Familytree|boxstyle=background: #E0FFFF;| | | | | | | | | | | | | | | | | | | | | | | |!| | | | | | | | | | | |}}
| |
| {{Familytree|boxstyle=background: #E0FFFF;| | | | | | | | | | | | | | | | | | | | | | | E05 | | | | | | | | | | | |E05= Fine needle aspiration cytology}}
| |
| {{Familytree/end}}
| |
|
| |
| ==References==
| |
| {{reflist|2}}
| |
| {{WH}}
| |
| {{WS}}
| |
| [[Category:Disease]]
| |
| [[Category:Endocrinology]]
| |
| [[Category:Up-To-Date]]
| |
| [[Category:Oncology]]
| |
| [[Category:Medicine]]
| |
| [[Category:Endocrinology]]
| |
| [[Category:Surgery]]
| |