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* [[Microangiopathic hemolytic anemia|Microangiopathic hemolytic anemia.]]<ref name="pmid481196">{{cite journal| author=Antman KH, Skarin AT, Mayer RJ, Hargreaves HK, Canellos GP| title=Microangiopathic hemolytic anemia and cancer: a review. | journal=Medicine (Baltimore) | year= 1979 | volume= 58 | issue= 5 | pages= 377-84 | pmid=481196 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=481196 }}</ref> | * [[Microangiopathic hemolytic anemia|Microangiopathic hemolytic anemia.]]<ref name="pmid481196">{{cite journal| author=Antman KH, Skarin AT, Mayer RJ, Hargreaves HK, Canellos GP| title=Microangiopathic hemolytic anemia and cancer: a review. | journal=Medicine (Baltimore) | year= 1979 | volume= 58 | issue= 5 | pages= 377-84 | pmid=481196 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=481196 }}</ref> | ||
* [[Membranous nephropathy|Membranous nephropathy.]]<ref name="pmid6986318">{{cite journal| author=Wakashin M, Wakashin Y, Iesato K, Ueda S, Mori Y, Tsuchida H et al.| title=Association of gastric cancer and nephrotic syndrome. An immunologic study in three patients. | journal=Gastroenterology | year= 1980 | volume= 78 | issue= 4 | pages= 749-56 | pmid=6986318 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6986318 }}</ref> | * [[Membranous nephropathy|Membranous nephropathy.]]<ref name="pmid6986318">{{cite journal| author=Wakashin M, Wakashin Y, Iesato K, Ueda S, Mori Y, Tsuchida H et al.| title=Association of gastric cancer and nephrotic syndrome. An immunologic study in three patients. | journal=Gastroenterology | year= 1980 | volume= 78 | issue= 4 | pages= 749-56 | pmid=6986318 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6986318 }}</ref> | ||
* [[Trousseau's syndrome]]: [[ | * [[Trousseau's syndrome]]: [[Hypercoagulable states]].<ref name="pmid19421245">{{cite journal| author=Carmack SW, Genta RM, Graham DY, Lauwers GY| title=Management of gastric polyps: a pathology-based guide for gastroenterologists. | journal=Nat Rev Gastroenterol Hepatol | year= 2009 | volume= 6 | issue= 6 | pages= 331-41 | pmid=19421245 | doi=10.1038/nrgastro.2009.70 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19421245 }}</ref> | ||
* [[Polyarteritis nodosa]].<ref name="pmid17142647">{{cite journal| author=Rugge M, Meggio A, Pennelli G, Piscioli F, Giacomelli L, De Pretis G et al.| title=Gastritis staging in clinical practice: the OLGA staging system. | journal=Gut | year= 2007 | volume= 56 | issue= 5 | pages= 631-6 | pmid=17142647 | doi=10.1136/gut.2006.106666 | pmc=1942143 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17142647 }}</ref> | * [[Polyarteritis nodosa]].<ref name="pmid17142647">{{cite journal| author=Rugge M, Meggio A, Pennelli G, Piscioli F, Giacomelli L, De Pretis G et al.| title=Gastritis staging in clinical practice: the OLGA staging system. | journal=Gut | year= 2007 | volume= 56 | issue= 5 | pages= 631-6 | pmid=17142647 | doi=10.1136/gut.2006.106666 | pmc=1942143 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17142647 }}</ref> | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
{{WH}} | |||
{{WS}} | |||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
[[Category:Conditions diagnosed by stool test]] | [[Category:Conditions diagnosed by stool test]] | ||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | [[Category:Oncology]] | ||
[[Category:Medicine]] | [[Category:Medicine]] | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
[[Category:Surgery]] | [[Category:Surgery]] | ||
Latest revision as of 00:18, 30 July 2020
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.; Parminder Dhingra, M.D. [2]
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Stomach cancer Microchapters |
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Overview
Patients with stomach cancer generally appear weak. Common physical examination findings include abdominal distention, palpation of an abdominal mass, and pallor. Leser-Trelat sign and presence of Virchow's node (left supraclavicular lymphadenopathy), Sister Mary Joseph nodule (visible periumbilical nodule), Blumer's shelf (rectal mass/shelf on rectal exam) and/or Trousseau's syndrome (migratory phlebitis) on physical examination are highly suggestive of stomach cancer
Physical Examination
General Appearance
- Patients with gastric cancer are generally weak due to weight loss.
Skin
- Pallor.
- Jaundice may appear if bile duct obstruction occurs.[1]
- Acanthosis nigricans: Velvety and hyperpigmented patches on skin folds.[2]
- Leser-Trelat sign: Acute-onset multiple seborrheic keratosis lesions that are usually located on the patient's back.[3]
Neck
Abdomen
- The presence of a palpable abdominal mass is the most common physical finding.[5]
- Abdominal distention.
- Sister Mary Joseph nodule: A visible periumbilical nodule that is highly suggestive of umbilical metastasis.
- Splenomegaly.
- Ascites: It can be the first indication of peritoneal carcinomatosis.
- A palpable liver mass: It is often multifocal or diffuse, usually associated with an elevation in the serum alkaline phosphatase concentration.
Rectum
- Blood on rectal exam.
- Blumer's shelf: Rectal mass/shelf palpable on rectal exam.[6]
Genitourinary
- Ovarian mass may be suggestive of Krukenberg syndome.[7]
Extremities
Paraneoplastic syndrome manifestations
- Microangiopathic hemolytic anemia.[8]
- Membranous nephropathy.[9]
- Trousseau's syndrome: Hypercoagulable states.[10]
- Polyarteritis nodosa.[11]
References
- ↑ Fuchs CS, Mayer RJ (1995). "Gastric carcinoma". N Engl J Med. 333 (1): 32–41. doi:10.1056/NEJM199507063330107. PMID 7776992.
- ↑ Muehldorfer SM, Stolte M, Martus P, Hahn EG, Ell C, Multicenter Study Group "Gastric Polyps" (2002). "Diagnostic accuracy of forceps biopsy versus polypectomy for gastric polyps: a prospective multicentre study". Gut. 50 (4): 465–70. PMC 1773183. PMID 11889063.
- ↑ Dantzig PI (1973). "Sign of Leser-Trélat". Arch Dermatol. 108 (5): 700–1. PMID 4270762.
- ↑ Morgenstern L (1979). "The Virchow-Troisier node: a historical note". Am J Surg. 138 (5): 703. PMID 386813.
- ↑ Wanebo HJ, Kennedy BJ, Chmiel J, Steele G, Winchester D, Osteen R (1993). "Cancer of the stomach. A patient care study by the American College of Surgeons". Ann Surg. 218 (5): 583–92. PMC 1243028. PMID 8239772.
- ↑ Winne BURCHARD BE (1965). "Blumer's shelf tumor with primary carcinoma of the lung. A case report". J Int Coll Surg. 44 (5): 477–81. PMID 5828299.
- ↑ Gilliland R, Gill PJ (1992). "Incidence and prognosis of Krukenberg tumour in Northern Ireland". Br J Surg. 79 (12): 1364–6. PMID 1336701.
- ↑ Antman KH, Skarin AT, Mayer RJ, Hargreaves HK, Canellos GP (1979). "Microangiopathic hemolytic anemia and cancer: a review". Medicine (Baltimore). 58 (5): 377–84. PMID 481196.
- ↑ Wakashin M, Wakashin Y, Iesato K, Ueda S, Mori Y, Tsuchida H; et al. (1980). "Association of gastric cancer and nephrotic syndrome. An immunologic study in three patients". Gastroenterology. 78 (4): 749–56. PMID 6986318.
- ↑ Carmack SW, Genta RM, Graham DY, Lauwers GY (2009). "Management of gastric polyps: a pathology-based guide for gastroenterologists". Nat Rev Gastroenterol Hepatol. 6 (6): 331–41. doi:10.1038/nrgastro.2009.70. PMID 19421245.
- ↑ Rugge M, Meggio A, Pennelli G, Piscioli F, Giacomelli L, De Pretis G; et al. (2007). "Gastritis staging in clinical practice: the OLGA staging system". Gut. 56 (5): 631–6. doi:10.1136/gut.2006.106666. PMC 1942143. PMID 17142647.