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{{CMG}}; {{AE}}{{Homa}} {{SC}}
{{CMG}}; {{AE}}{{Homa}} {{SC}}
==Overview==
==Overview==
The majority of patients with [disease name] are asymptomatic.
The majority of [[patients]] with renal oncocytoma are [[asymptomatic]]. [[Symptoms]] are seen in almost only 17% to 21% of [[patients]] with  renal oncocytoma. [[Symptoms]] of renal oncocytoma include [[hematuria]], [[flank pain]], [[abdominal]] or [[flank]] [[mass]] and [[weight loss]].
 
OR
 
The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].


==History and Symptoms==
==History and Symptoms==
*The majority of patients with renal oncocytoma are asymptomatic.<ref>{{Cite journal
*The majority of [[patients]] with renal oncocytoma are [[asymptomatic]].<ref>{{Cite journal
  | author = [[H. Choi]], [[U. A. Almagro]], [[J. T. McManus]], [[D. H. Norback]] & [[S. C. Jacobs]]
  | author = [[H. Choi]], [[U. A. Almagro]], [[J. T. McManus]], [[D. H. Norback]] & [[S. C. Jacobs]]
  | title = Renal oncocytoma. A clinicopathologic study
  | title = Renal oncocytoma. A clinicopathologic study
Line 31: Line 27:
  | pmid = 8990136
  | pmid = 8990136
}}</ref>
}}</ref>
*Symptoms are seen in almost 17% to 21% of patients with  renal oncocytoma.
*[[Symptoms]] are seen in almost only 17% to 21% of [[patients]] with  renal oncocytoma.<ref>{{Cite journal
*Symptoms of renal oncocytoma include [[hematuria]], [[flank pain]], [[abdominal mass]] and [[weight loss]].<ref>{{Cite journal
| author = [[M. J. Klein]] & [[Q. J. Valensi]]
| title = Proximal tubular adenomas of kidney with so-called oncocytic features. A clinicopathologic study of 13 cases of a rarely reported neoplasm
| journal = [[Cancer]]
| volume = 38
| issue = 2
| pages = 906–914
| year = 1976
| month = August
| pmid = 975006
}}</ref><ref>{{Cite journal
| author = [[B. Perez-Ordonez]], [[G. Hamed]], [[S. Campbell]], [[R. A. Erlandson]], [[P. Russo]], [[P. B. Gaudin]] & [[V. E. Reuter]]
| title = Renal oncocytoma: a clinicopathologic study of 70 cases
| journal = [[The American journal of surgical pathology]]
| volume = 21
| issue = 8
| pages = 871–883
| year = 1997
| month = August
| pmid = 9255250
}}</ref><ref>{{Cite journal
| author = [[M. B. Amin]], [[T. B. Crotty]], [[S. K. Tickoo]] & [[G. M. Farrow]]
| title = Renal oncocytoma: a reappraisal of morphologic features with clinicopathologic findings in 80 cases
| journal = [[The American journal of surgical pathology]]
| volume = 21
| issue = 1
| pages = 1–12
| year = 1997
| month = January
| pmid = 8990136
}}</ref>
   
*[[Symptoms]] of renal oncocytoma include [[hematuria]], [[flank pain]], [[abdominal]] or [[flank]] [[mass]] and [[weight loss]].<ref name="LieberHosaka1987">{{cite journal|last1=Lieber|first1=M. M.|last2=Hosaka|first2=Y.|last3=Tsukamoto|first3=T.|title=Renal oncocytoma|journal=World Journal of Urology|volume=5|issue=2|year=1987|pages=71–79|issn=0724-4983|doi=10.1007/BF00327060}}</ref><ref>{{Cite journal
  | author = [[B. Perez-Ordonez]], [[G. Hamed]], [[S. Campbell]], [[R. A. Erlandson]], [[P. Russo]], [[P. B. Gaudin]] & [[V. E. Reuter]]
  | author = [[B. Perez-Ordonez]], [[G. Hamed]], [[S. Campbell]], [[R. A. Erlandson]], [[P. Russo]], [[P. B. Gaudin]] & [[V. E. Reuter]]
  | title = Renal oncocytoma: a clinicopathologic study of 70 cases
  | title = Renal oncocytoma: a clinicopathologic study of 70 cases
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}}</ref>
}}</ref>
===Symptoms===
===Symptoms===
Symptoms of renal oncocytoma include:<ref>{{Cite journal
[[Symptoms]] of renal oncocytoma include:<ref>{{Cite journal
  | author = [[B. Perez-Ordonez]], [[G. Hamed]], [[S. Campbell]], [[R. A. Erlandson]], [[P. Russo]], [[P. B. Gaudin]] & [[V. E. Reuter]]
  | author = [[B. Perez-Ordonez]], [[G. Hamed]], [[S. Campbell]], [[R. A. Erlandson]], [[P. Russo]], [[P. B. Gaudin]] & [[V. E. Reuter]]
  | title = Renal oncocytoma: a clinicopathologic study of 70 cases
  | title = Renal oncocytoma: a clinicopathologic study of 70 cases
Line 136: Line 163:
  | doi = 10.1097/00005392-199907000-00010
  | doi = 10.1097/00005392-199907000-00010
  | pmid = 10379735
  | pmid = 10379735
}}</ref>
}}</ref><ref name="LieberHosaka1987">{{cite journal|last1=Lieber|first1=M. M.|last2=Hosaka|first2=Y.|last3=Tsukamoto|first3=T.|title=Renal oncocytoma|journal=World Journal of Urology|volume=5|issue=2|year=1987|pages=71–79|issn=0724-4983|doi=10.1007/BF00327060}}</ref>
 
*[[Hematuria]]
*[[Hematuria]]
*[[Flank pain]]
*[[Flank pain]]
*[[Abdominal mass]]  
*[[Abdominal]] or [[flank]] [[mass]]  
*[[Weight loss]]
*[[Weight loss]]
Less common symptoms of [disease name] include
*[Symptom 1]
*[Symptom 2]
*[Symptom 3]
Because of their well-circumscribed, generally noninvasive growth pattern few renal oncocytomas are symptomatic but are instead detected incidentally during an evaluation for some unrelated symptom, or even at postmortem examination. This feature was noted in Klein and Valensi’s [2] initial series and has been validated by contemporary reports, which suggest that only 17% to 21% of patients with oncocytoma present with symptoms [2,4,7]. Gross hematuria precipitated work-up in 3% to 9% of patients, flank pain in 3% to 4%, and abdominal mass in 3% to 4% [4,7].
More than 50% of patients with oncocytomas are asymptomatic . Flank pain, a palpable mass, gross or microscopic hematuria, or weight loss is seen in some patients .
Other clinical features: Bilateral or multifocal oncocytomas are sometimes seen The coexistence of oncocytoma and renal cell carcinoma has also been reported. An association with angiomyolipoma or tuberculous sclerosis in some patients has been reported . The occurrence of oncocytoma in transplant patients has also been reported (Rostaing et al., 1994). Familial cases of oncocytoma have also been found .
==References==
==References==
{{reflist|2}}
{{reflist|2}}
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[[Category:Oncology]]
[[Category:Oncology]]
[[Category:Nephrology]]
[[Category:Nephrology]]
[[Category: Primary care]]
[[Category:Disease]]
[[Category:Disease]]

Latest revision as of 23:57, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Homa Najafi, M.D.[2] Shanshan Cen, M.D. [3]

Overview

The majority of patients with renal oncocytoma are asymptomatic. Symptoms are seen in almost only 17% to 21% of patients with renal oncocytoma. Symptoms of renal oncocytoma include hematuria, flank pain, abdominal or flank mass and weight loss.

History and Symptoms

Symptoms

Symptoms of renal oncocytoma include:[13][14][9][15][16][17][6]

References

  1. ↑ H. Choi, U. A. Almagro, J. T. McManus, D. H. Norback & S. C. Jacobs (1983). "Renal oncocytoma. A clinicopathologic study". Cancer. 51 (10): 1887–1896. PMID 6831354. Unknown parameter |month= ignored (help)
  2. ↑ M. B. Amin, T. B. Crotty, S. K. Tickoo & G. M. Farrow (1997). "Renal oncocytoma: a reappraisal of morphologic features with clinicopathologic findings in 80 cases". The American journal of surgical pathology. 21 (1): 1–12. PMID 8990136. Unknown parameter |month= ignored (help)
  3. ↑ M. J. Klein & Q. J. Valensi (1976). "Proximal tubular adenomas of kidney with so-called oncocytic features. A clinicopathologic study of 13 cases of a rarely reported neoplasm". Cancer. 38 (2): 906–914. PMID 975006. Unknown parameter |month= ignored (help)
  4. ↑ B. Perez-Ordonez, G. Hamed, S. Campbell, R. A. Erlandson, P. Russo, P. B. Gaudin & V. E. Reuter (1997). "Renal oncocytoma: a clinicopathologic study of 70 cases". The American journal of surgical pathology. 21 (8): 871–883. PMID 9255250. Unknown parameter |month= ignored (help)
  5. ↑ M. B. Amin, T. B. Crotty, S. K. Tickoo & G. M. Farrow (1997). "Renal oncocytoma: a reappraisal of morphologic features with clinicopathologic findings in 80 cases". The American journal of surgical pathology. 21 (1): 1–12. PMID 8990136. Unknown parameter |month= ignored (help)
  6. ↑ 6.0 6.1 Lieber, M. M.; Hosaka, Y.; Tsukamoto, T. (1987). "Renal oncocytoma". World Journal of Urology. 5 (2): 71–79. doi:10.1007/BF00327060. ISSN 0724-4983.
  7. ↑ B. Perez-Ordonez, G. Hamed, S. Campbell, R. A. Erlandson, P. Russo, P. B. Gaudin & V. E. Reuter (1997). "Renal oncocytoma: a clinicopathologic study of 70 cases". The American journal of surgical pathology. 21 (8): 871–883. PMID 9255250. Unknown parameter |month= ignored (help)
  8. ↑ M. M. Lieber, K. M. Tomera & G. M. Farrow (1981). "Renal oncocytoma". The Journal of urology. 125 (4): 481–485. PMID 7218443. Unknown parameter |month= ignored (help)
  9. ↑ 9.0 9.1 Neisius, D.; Braedel, H. U.; Schindler, E.; Hoene, E.; Alloussi, Sch. (1988). "Computed tomographic and angiographic findings in renal oncocytoma". The British Journal of Radiology. 61 (731): 1019–1025. doi:10.1259/0007-1285-61-731-1019. ISSN 0007-1285.
  10. ↑ M. R. Licht, A. C. Novick, R. R. Tubbs, E. A. Klein, H. S. Levin & S. B. Streem (1993). "Renal oncocytoma: clinical and biological correlates". The Journal of urology. 150 (5 Pt 1): 1380–1383. PMID 8411404. Unknown parameter |month= ignored (help)
  11. ↑ F. Bertoni, C. Ferri, P. Bacchini, G. Corrado, A. Benati, D. Mannini & F. Corrado (1989). "Oncocytoma and low-grade oncocytic carcinoma of the kidney". European urology. 16 (2): 101–109. PMID 2714326.
  12. ↑ C. B. Dechet, D. G. Bostwick, M. L. Blute, S. C. Bryant & H. Zincke (1999). "Renal oncocytoma: multifocality, bilateralism, metachronous tumor development and coexistent renal cell carcinoma". The Journal of urology. 162 (1): 40–42. doi:10.1097/00005392-199907000-00010. PMID 10379735. Unknown parameter |month= ignored (help)
  13. ↑ B. Perez-Ordonez, G. Hamed, S. Campbell, R. A. Erlandson, P. Russo, P. B. Gaudin & V. E. Reuter (1997). "Renal oncocytoma: a clinicopathologic study of 70 cases". The American journal of surgical pathology. 21 (8): 871–883. PMID 9255250. Unknown parameter |month= ignored (help)
  14. ↑ M. M. Lieber, K. M. Tomera & G. M. Farrow (1981). "Renal oncocytoma". The Journal of urology. 125 (4): 481–485. PMID 7218443. Unknown parameter |month= ignored (help)
  15. ↑ M. R. Licht, A. C. Novick, R. R. Tubbs, E. A. Klein, H. S. Levin & S. B. Streem (1993). "Renal oncocytoma: clinical and biological correlates". The Journal of urology. 150 (5 Pt 1): 1380–1383. PMID 8411404. Unknown parameter |month= ignored (help)
  16. ↑ F. Bertoni, C. Ferri, P. Bacchini, G. Corrado, A. Benati, D. Mannini & F. Corrado (1989). "Oncocytoma and low-grade oncocytic carcinoma of the kidney". European urology. 16 (2): 101–109. PMID 2714326.
  17. ↑ C. B. Dechet, D. G. Bostwick, M. L. Blute, S. C. Bryant & H. Zincke (1999). "Renal oncocytoma: multifocality, bilateralism, metachronous tumor development and coexistent renal cell carcinoma". The Journal of urology. 162 (1): 40–42. doi:10.1097/00005392-199907000-00010. PMID 10379735. Unknown parameter |month= ignored (help)

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