Oligodendroglioma history and symptoms: Difference between revisions
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***[[Urgency|Urge]] to [[sleep]] | ***[[Urgency|Urge]] to [[sleep]] | ||
***[[Loss function|Loss]] of [[Interest (emotion)|interest]] in [[Activities of daily living|daily activities]] | ***[[Loss function|Loss]] of [[Interest (emotion)|interest]] in [[Activities of daily living|daily activities]] | ||
***Abulia (showing abnormal inability to act or make decisions) | ***[[Abulia]] (showing [[abnormal]] inability to act or [[Decision making|make decisions]]) | ||
***Lack of spontaneity | ***[[Lack (manque)|Lack]] of spontaneity | ||
**'''Increased intracranial pressure''' (either due to a large mass or any restriction in cerebrospinal fluid outflow causing hydrocephalus) associated with following symptoms: | **'''[[Increased intracranial pressure]]''' (either due to a [[Large-print|large]] [[mass]] or any [[restriction]] in [[cerebrospinal fluid]] outflow [[Causes|causing]] [[hydrocephalus]]) [[Association (statistics)|associated]] with following [[symptoms]]: | ||
***Classic triad that includes: | ***Classic [[Triad (anatomy)|triad]] that includes: | ||
****Headache | ****[[Headache]] | ||
****Nausea | ****[[Nausea]] | ||
****Papilledema | ****[[Papilledema]] | ||
***Loss of consciousness with syncope (maybe associated with a few tonic-clonic jerks) | ***[[Loss of consciousness]] with [[syncope]] (maybe [[Association (statistics)|associated]] with a few [[tonic-clonic]] [[Jerking|jerks]]) | ||
{| class="wikitable" | {| class="wikitable" | ||
|+Oligodendrogliomas symptoms according to tumor site | |+Oligodendrogliomas symptoms according to tumor site | ||
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! style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|Clinical features}} | ! style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|Clinical features}} | ||
|- | |- | ||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |'''Frontal lobe''' | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |'''[[Frontal lobe]]''' | ||
| | | | ||
* Weakness of one side of the body | * [[Weakness]] of one [[Side chain|side]] of the [[Human body|body]] | ||
* Personality changes | * [[Personality changes]] | ||
* Behavior changes | * [[Behavior change|Behavior changes]] | ||
* Difficulty with short-term memory | * Difficulty with [[short-term memory]] | ||
|- | |- | ||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |'''Temporal lobe''' | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |'''[[Temporal lobe]]''' | ||
| | | | ||
* Usually | * Usually “[[Silent News|silent]]” | ||
* May cause few symptoms such as: | * May [[Causes|cause]] few [[symptoms]] such as: | ||
** Seizures | ** [[Seizures]] | ||
** Language problems | ** [[Language]] [[Problem Solved|problems]] | ||
|} | |} | ||
Latest revision as of 22:26, 18 May 2019
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Oligodendroglioma Microchapters |
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Oligodendroglioma history and symptoms On the Web |
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Risk calculators and risk factors for Oligodendroglioma history and symptoms |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2]Sujit Routray, M.D. [3]
Overview
When evaluating a patient for oligodendroglioma, a detailed history of the presenting symptom (onset, duration, and progression), other associated symptoms, a thorough past medical history review, and review of common risk factors such as family history of brain tumors. Oligodendroglioma is a slow-growing, infiltrative tumor that may be clinically silent for many years. With tumor progression, symptoms may vary depending upon the location, size, and rate of tumor growth. Oligodendroglioma mainly involves the frontal lobe. Symptoms associated with oligodendroglioma include seizure, headache, nausea, vomiting, vertigo, visual loss, diplopia, strabismus, muscle weakness, numbness, speech difficulties, mood disturbances, personality changes, memory problems, low energy, fatigue, urge to sleep, loss of interest in daily activities, abulia, lack of spontaneity, loss of consciousness with syncope (few tonic-clonic jerks), and classic triad of headache, nausea, and papilledema due to raised intracranial pressure.
History
- While evaluating a patient for oligodendroglioma, a detailed history of the following should be taken:[1]
- Presenting symptom:
- Onset
- Duration
- Progression
- Other associated symptoms
- A thorough past medical history review
- Review of common risk factors such as:
- Presenting symptom:
Symptoms
- Oligodendroglioma is a slow-growing, infiltrative tumor that may be clinically silent for many years
- Asymptomatic patients are diagnosed based on incidental findings at the time of brain imaging performed for another reason (e.g: trauma, migraine headaches)
- Focal neurologic deficits and generalized symptoms such as headache are uncommon at the time of diagnosis
- With tumor progression, symptoms may vary depending on following characteristics of tumor:
- It mainly involves the frontal lobe
- Common symptoms associated with oligodendroglioma include:[2][3][4][5][6]
- Seizure (usually the first and most common presentation in 50-80% of the cases)[7]
- Headache
- Nausea
- Vomiting
- Vertigo
- Focal neurological deficits depending upon tumor location (symptoms usually caused by local tissue disruption, mass effect on nearby structures, or vasogenic edema) include:
- Cognitive dysfunction includes:
- Memory problems
- Changes in mood
- Changes in personality
- Low energy
- Fatigue
- Urge to sleep
- Loss of interest in daily activities
- Abulia (showing abnormal inability to act or make decisions)
- Lack of spontaneity
- Increased intracranial pressure (either due to a large mass or any restriction in cerebrospinal fluid outflow causing hydrocephalus) associated with following symptoms:
- Classic triad that includes:
- Loss of consciousness with syncope (maybe associated with a few tonic-clonic jerks)
| Tumor site of involvement | Clinical features |
|---|---|
| Frontal lobe |
|
| Temporal lobe |
References
- ↑ McCarthy BJ, Rankin KM, Aldape K, Bondy ML, Brännström T, Broholm H; et al. (2011). "Risk factors for oligodendroglial tumors: a pooled international study". Neuro Oncol. 13 (2): 242–50. doi:10.1093/neuonc/noq173. PMC 3064625. PMID 21149253.
- ↑ Douay X, Daems-Monpeurt C, Labalette P, Blond S, Petit H (1997). "[Bilateral 3rd cranial nerve palsy disclosing oligodendroglioma]". Rev Neurol (Paris). 153 (6–7): 430–2. PMID 9684012.
- ↑ Hata N, Shono T, Mizoguchi M, Matsumoto K, Guan Y, Nagata S; et al. (2007). "Loss of heterozygosity analysis in an anaplastic oligodendroglioma arising after radiation therapy". Neurol Res. 29 (7): 723–6. doi:10.1179/016164107X208068. PMID 17553214.
- ↑ Ogasawara H, Kiya K, Uozumi T, Sugiyama K, Kawamoto K, Ohta M (1990). "Multiple oligodendroglioma--case report". Neurol Med Chir (Tokyo). 30 (2): 127–31. PMID 1695334.
- ↑ Raciti-Daurio C, Caruso J (1990). "Oligodendroglioma--a case presentation". Optom Vis Sci. 67 (1): 56–8. PMID 2308753.
- ↑ Rodriguez FJ, Tihan T, Lin D, McDonald W, Nigro J, Feuerstein B; et al. (2014). "Clinicopathologic features of pediatric oligodendrogliomas: a series of 50 patients". Am J Surg Pathol. 38 (8): 1058–70. doi:10.1097/PAS.0000000000000221. PMC 4322928. PMID 24805856.
- ↑ Cavaliere R, Farace E, Schiff D (2006). "Clinical implications of status epilepticus in patients with neoplasms". Arch Neurol. 63 (12): 1746–9. doi:10.1001/archneur.63.12.1746. PMID 17172614.