Radiation proctitis differential diagnosis: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
[[Image:Home_logo1.png|right|250px|link=https://www.wikidoc.org/index.php/Radiation_proctitis]] | [[Image:Home_logo1.png|right|250px|link=https://www.wikidoc.org/index.php/Radiation_proctitis]] | ||
{{CMG}} {{AE}} | {{CMG}} {{AE}} [[User:Rekha|Rekha, M.D.]], {{MIR}} | ||
==Overview== | ==Overview== | ||
Radiation proctitis must be differentiated from [[infectious colitis]],[[inflammatory bowel disease]],[[Ischemic colitis,|ischemic colitis]],medication-associated colitis,[[chemical colitis]] and [[allergic colitis]] | |||
==Differentiating Radiation proctitis from other Diseases== | |||
The following conditions may present in a similar manner as radiation proctitis, and should be excluded:<ref name="pmid8677984">{{cite journal| author=Babb RR| title=Radiation proctitis: a review. | journal=Am J Gastroenterol | year= 1996 | volume= 91 | issue= 7 | pages= 1309-11 | pmid=8677984 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8677984 }}</ref> | |||
* [[Infectious colitis]], | |||
* [[Inflammatory bowel disease]], | |||
==Differentiating | * [[Ischemic colitis,|Ischemic colitis]], | ||
* Medication-associated colitis | |||
* [[Chemical colitis]] | |||
The following conditions may present in a similar manner as radiation proctitis, and should be excluded: | * [[Allergic colitis]] | ||
* | The table below lists the [[differential diagnosis]] of common causes of colitis: | ||
* | {| | ||
* [[Ischemic colitis,| | |||
* | |||
* | |||
[ | |||
{| | |||
|- style="background: #4479BA; color: #FFFFFF; text-align: center;" | |- style="background: #4479BA; color: #FFFFFF; text-align: center;" | ||
! rowspan="2" |Diseases | ! rowspan="2" |Diseases | ||
! colspan=" | ! colspan="5" |History and Symptoms | ||
! colspan="4" |Physical Examination | ! colspan="4" |Physical Examination | ||
! colspan=" | ! colspan="4" |Laboratory findings | ||
|- style="background: #4479BA; color: #FFFFFF; text-align: center;" | |- style="background: #4479BA; color: #FFFFFF; text-align: center;" | ||
!Diarrhea | !Diarrhea | ||
!Rectal bleeding | !Rectal bleeding | ||
!Abdominal pain | !Abdominal pain | ||
!Radiation exposure | |||
!Atopy | !Atopy | ||
!Dehydration | !Dehydration | ||
!Fever | !Fever | ||
Line 48: | Line 32: | ||
!Blood in stool (frank or occult) | !Blood in stool (frank or occult) | ||
!Microorganism in stool | !Microorganism in stool | ||
!Imaging | |||
!Pseudomembranes on endoscopy | !Pseudomembranes on endoscopy | ||
|- | |- | ||
Line 54: | Line 39: | ||
| style="background: #F5F5F5; padding: 5px;" | ++ | | style="background: #F5F5F5; padding: 5px;" | ++ | ||
| style="background: #F5F5F5; padding: 5px;" | + | | style="background: #F5F5F5; padding: 5px;" | + | ||
| style="background: #F5F5F5; padding: 5px;" |- | |||
| style="background: #F5F5F5; padding: 5px;" | ++ | | style="background: #F5F5F5; padding: 5px;" | ++ | ||
| style="background: #F5F5F5; padding: 5px;" |- | |||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |- | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |- | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |- | ||
| style="background: #F5F5F5; padding: 5px;" | | |||
| style="background: #F5F5F5; padding: 5px;" | ++ | | style="background: #F5F5F5; padding: 5px;" | ++ | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |- | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |- | ||
| style="background: #F5F5F5; padding: 5px;" |- | |||
|- | |- | ||
| style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Chemical colitis]] | | style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Chemical colitis]] | ||
Line 68: | Line 54: | ||
| style="background: #F5F5F5; padding: 5px;" | ++ | | style="background: #F5F5F5; padding: 5px;" | ++ | ||
| style="background: #F5F5F5; padding: 5px;" | ++ | | style="background: #F5F5F5; padding: 5px;" | ++ | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |- | ||
| | | style="background: #F5F5F5; padding: 5px;" |- | ||
| style="background: #F5F5F5; padding: 5px;" | + | | style="background: #F5F5F5; padding: 5px;" | + | ||
| style="background: #F5F5F5; padding: 5px;" | + | | style="background: #F5F5F5; padding: 5px;" | + | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |- | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |- | ||
| style="background: #F5F5F5; padding: 5px;" | ++ | | style="background: #F5F5F5; padding: 5px;" | ++ | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |- | ||
| style="background: #F5F5F5; padding: 5px;" |- | |||
| style="background: #F5F5F5; padding: 5px;" | + | | style="background: #F5F5F5; padding: 5px;" | + | ||
|- | |- | ||
Line 82: | Line 69: | ||
| style="background: #F5F5F5; padding: 5px;" | ++ | | style="background: #F5F5F5; padding: 5px;" | ++ | ||
| style="background: #F5F5F5; padding: 5px;" | ++ | | style="background: #F5F5F5; padding: 5px;" | ++ | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |- | ||
| | | style="background: #F5F5F5; padding: 5px;" |- | ||
| style="background: #F5F5F5; padding: 5px;" | +++ | | style="background: #F5F5F5; padding: 5px;" | +++ | ||
| style="background: #F5F5F5; padding: 5px;" | +++ | | style="background: #F5F5F5; padding: 5px;" | +++ | ||
Line 90: | Line 77: | ||
| style="background: #F5F5F5; padding: 5px;" | ++ | | style="background: #F5F5F5; padding: 5px;" | ++ | ||
| style="background: #F5F5F5; padding: 5px;" | ++ | | style="background: #F5F5F5; padding: 5px;" | ++ | ||
| style="background: #F5F5F5; padding: 5px;" |CT shows bowel wall thickening and edema | |||
| style="background: #F5F5F5; padding: 5px;" | + | | style="background: #F5F5F5; padding: 5px;" | + | ||
|- | |- | ||
Line 96: | Line 84: | ||
| style="background: #F5F5F5; padding: 5px;" | ++ | | style="background: #F5F5F5; padding: 5px;" | ++ | ||
| style="background: #F5F5F5; padding: 5px;" | + | | style="background: #F5F5F5; padding: 5px;" | + | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | ++ | ||
| | | style="background: #F5F5F5; padding: 5px;" |- | ||
| style="background: #F5F5F5; padding: 5px;" | + | | style="background: #F5F5F5; padding: 5px;" | + | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |- | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |- | ||
| style="background: #F5F5F5; padding: 5px;" | + | | style="background: #F5F5F5; padding: 5px;" | + | ||
| style="background: #F5F5F5; padding: 5px;" | ++ | | style="background: #F5F5F5; padding: 5px;" | ++ | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |- | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |- | ||
| style="background: #F5F5F5; padding: 5px;" |- | |||
|- | |- | ||
| style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Ischemic colitis]] | | style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Ischemic colitis]] | ||
Line 110: | Line 99: | ||
| style="background: #F5F5F5; padding: 5px;" | + | | style="background: #F5F5F5; padding: 5px;" | + | ||
| style="background: #F5F5F5; padding: 5px;" | ++ | | style="background: #F5F5F5; padding: 5px;" | ++ | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |- | ||
| | | style="background: #F5F5F5; padding: 5px;" |- | ||
| style="background: #F5F5F5; padding: 5px;" | + | |||
| style="background: #F5F5F5; padding: 5px;" | + | | style="background: #F5F5F5; padding: 5px;" | + | ||
| style="background: #F5F5F5; padding: 5px;" | + | | style="background: #F5F5F5; padding: 5px;" | + | ||
| style="background: #F5F5F5; padding: 5px;" | + | | style="background: #F5F5F5; padding: 5px;" | + | ||
| style="background: #F5F5F5; padding: 5px;" | ++ | |||
| style="background: #F5F5F5; padding: 5px;" |- | |||
| style="background: #F5F5F5; padding: 5px;" |Abdomen xray shows distention and pneumonitis | |||
CT scan suggestive of double halo appearance and thumb printing sign | |||
| style="background: #F5F5F5; padding: 5px;" |- | |||
|- | |||
| style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Inflamatory bowel disease|Inflammatory bowel disease]] | |||
| style="background: #F5F5F5; padding: 5px;" | ++ | |||
| style="background: #F5F5F5; padding: 5px;" | ++ | |||
| style="background: #F5F5F5; padding: 5px;" |Diffuse + | |||
| style="background: #F5F5F5; padding: 5px;" |- | |||
| style="background: #F5F5F5; padding: 5px;" |- | |||
| style="background: #F5F5F5; padding: 5px;" | +/- | |||
| style="background: #F5F5F5; padding: 5px;" | +/- | |||
| style="background: #F5F5F5; padding: 5px;" |- | |||
| style="background: #F5F5F5; padding: 5px;" | + | | style="background: #F5F5F5; padding: 5px;" | + | ||
| style="background: #F5F5F5; padding: 5px;" | ++ | | style="background: #F5F5F5; padding: 5px;" | ++ | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |- | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |String sign on abdominal xray in Crohn's | ||
| style="background: #F5F5F5; padding: 5px;" |- | |||
|- | |- | ||
| style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Drug-induced colitis]] | | style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Drug-induced colitis|Medication induced colitis]] | ||
| style="background: #F5F5F5; padding: 5px;" | + | | style="background: #F5F5F5; padding: 5px;" | + | ||
| style="background: #F5F5F5; padding: 5px;" | + | | style="background: #F5F5F5; padding: 5px;" | + | ||
| style="background: #F5F5F5; padding: 5px;" | ++ | | style="background: #F5F5F5; padding: 5px;" | ++ | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |- | ||
| | | style="background: #F5F5F5; padding: 5px;" |- | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |- | ||
| style="background: #F5F5F5; padding: 5px;" | + | | style="background: #F5F5F5; padding: 5px;" | + | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |- | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |- | ||
| style="background: #F5F5F5; padding: 5px;" | ++ | | style="background: #F5F5F5; padding: 5px;" | ++ | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |- | ||
| style="background: #F5F5F5; padding: 5px;" |- | |||
| style="background: #F5F5F5; padding: 5px;" | + | | style="background: #F5F5F5; padding: 5px;" | + | ||
|- | |||
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|} | |} | ||
Latest revision as of 23:52, 6 November 2019
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Rekha, M.D., Mahshid Mir, M.D. [2]
Overview
Radiation proctitis must be differentiated from infectious colitis,inflammatory bowel disease,ischemic colitis,medication-associated colitis,chemical colitis and allergic colitis
Differentiating Radiation proctitis from other Diseases
The following conditions may present in a similar manner as radiation proctitis, and should be excluded:[1]
- Infectious colitis,
- Inflammatory bowel disease,
- Ischemic colitis,
- Medication-associated colitis
- Chemical colitis
- Allergic colitis
The table below lists the differential diagnosis of common causes of colitis:
Diseases | History and Symptoms | Physical Examination | Laboratory findings | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Diarrhea | Rectal bleeding | Abdominal pain | Radiation exposure | Atopy | Dehydration | Fever | Hypotension | Malnutrition | Blood in stool (frank or occult) | Microorganism in stool | Imaging | Pseudomembranes on endoscopy | |
Allergic Colitis | + | ++ | + | - | ++ | - | - | - | - | ++ | - | - | - |
Chemical colitis | + | ++ | ++ | - | - | + | + | - | - | ++ | - | - | + |
Infectious colitis | ++ | ++ | ++ | - | - | +++ | +++ | ++ | + | ++ | ++ | CT shows bowel wall thickening and edema | + |
Radiation proctitis | + | ++ | + | ++ | - | + | - | - | + | ++ | - | - | - |
Ischemic colitis | + | + | ++ | - | - | + | + | + | + | ++ | - | Abdomen xray shows distention and pneumonitis
CT scan suggestive of double halo appearance and thumb printing sign |
- |
Inflammatory bowel disease | ++ | ++ | Diffuse + | - | - | +/- | +/- | - | + | ++ | - | String sign on abdominal xray in Crohn's | - |
Medication induced colitis | + | + | ++ | - | - | - | + | - | - | ++ | - | - | + |
References
- ↑ Babb RR (1996). "Radiation proctitis: a review". Am J Gastroenterol. 91 (7): 1309–11. PMID 8677984.