Germ cell tumor classification: Difference between revisions

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! style="background: #4479BA; padding: 5px 5px;" rowspan=1 | {{fontcolor|#FFFFFF| Types}}
! style="background: #4479BA; padding: 5px 5px;" rowspan=1 | {{fontcolor|#FFFFFF|Subtypes}}
! style="background: #4479BA; padding: 5px 5px;" colspan=1 | {{fontcolor|#FFFFFF|Signs and Symptoms}}
! style="background: #4479BA; padding: 5px 5px;" rowspan=1 | {{fontcolor|#FFFFFF|Histopathology}}
! style="background: #4479BA; padding: 5px 5px;" rowspan=1 | {{fontcolor|#FFFFFF| Lab finding }}
! style="background: #4479BA; padding: 5px 5px;" colspan=1 | {{fontcolor|#FFFFFF| Treatment }}
! style="background: #4479BA; padding: 5px 5px;" rowspan=1 | {{fontcolor|#FFFFFF| Prognosis}}
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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold;" rowspan="3;"|Gonadal'''
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Seminoma
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* Painless [[testicular mass]] with discomfort
* [[Back pain]]
* [[Abdominal discomfort]]
* [[Abdominal mass]].
| style="padding: 5px 5px; background: #F5F5F5;" |Gross: pale gray to yellow nodules that are uniform or slightly lobulated and often bulge from the cut surface
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* Complete blood count and blood chemistry tests.
* Abnormal serum tumor marker levels ([[LDH]], [[HCG]]).<ref name="Diagnosisoftesticularcancer1" />
* CT: Metastases to the para-aortic, inguinal, or iliac lymph nodes. Visceral metastasis may also be seen.
* Pelvic MRI: may be diagnostic. multinodular tumors of uniform signal intensity
* Hypo- to isointense on T2-weighted images and inhomogenous enhancement on contrast enhanced T1-weighted images.
* Other diagnostic studies for seminoma include [[biopsy]], [[PET|FDG-PET scan]], and [[bone scan]].
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* [[Orchiectomy|Radical inguinal orchiectomy]] is the first treatment for any stage of testicular seminoma. Usually done as diagnostic and therapeutic.
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* Prognosis of seminoma is good for all stages with greater than 90% cure rate.
* The International Germ Cell Cancer Consensus Group divides seminoma into two prognosis groups: good and intermediate.
* Common complications of seminoma include recurrence, lymph node metastasis, distant metastasis, and secondary malignancies.
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Dysgerminoma


(Ovarian germ cell tumor)
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* Depend on the type of the [[tumor]] and its potential to produce [[hormonal]]<nowiki/>materials
* [[Abdominal pain]] or distention
* [[Menstrual irregularities]]
* Symptoms of [[virilization]]
* Rapidly growing [[abdominal]]/[[pelvic]] [[mass]]
* [[Acute abdominal pain]] from [[complications]] such as:
* *  [[Necrosis]]
* * [[Capsule|Capsular]] distention
* [[Rupture|* Rupture]] or [[torsion]] and or simply they can be [[asymptomatic]].
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Germinoma
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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold;" rowspan="6;" | Extragonadal
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold;" rowspan="1;"| Embryonic
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*
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Teratoma
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Extraembryonic
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Coriocarcinoma
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Yolk sac tumor
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<references />

Latest revision as of 14:23, 23 September 2019