Extranodal NK-T-cell lymphoma epidemiology and demographics: Difference between revisions
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==Overview== | ==Overview== | ||
NK cell lymphoma shows a poor [[prognosis]] because of rapid local progression and distant [[metastasis]].The [[median]] age of onset is approximately 50 years and it is common in elderly. [[extranodal NK/T-cell lymphoma]] is a rare disease in children and often it is associated with mosquito-bite [[hypersensitivity]] or other [[EBV]]-associated disease[[Natural Killer cell|.Natural Killer (NK) cell]] lymphoma is a rare disease. [[Extranodal NK-T-cell lymphoma|extranodal NK/T cell lymphoma]], nasal type (NKTCL) and aggressive NK-cell leukemia (ANKCL) have a higher incidence in Asia, Central, and South America.NK T cell lymphoma, nasal type (NNKTL) consist 3000-10000 out of 100000 cases of [[non-Hodgkin lymphoma]] in Asia and South America and less than 1000 in 10000 patient in western countries<br /> | |||
== Epidemiology and Demographics == | |||
=== Mortality rate === | |||
* NK cell lymphoma shows a poor [[prognosis]] because of rapid local progression and distant [[Metastasis - brain|metastasis]].<ref name="JaffeNicolae2013">{{cite journal|last1=Jaffe|first1=Elaine S|last2=Nicolae|first2=Alina|last3=Pittaluga|first3=Stefania|title=Peripheral T-cell and NK-cell lymphomas in the WHO classification: pearls and pitfalls|journal=Modern Pathology|volume=26|issue=S1|year=2013|pages=S71–S87|issn=0893-3952|doi=10.1038/modpathol.2012.181}}</ref> | |||
=== Age === | |||
* The [[median]] age of onset is approximately 50 years and it is common in the elderly. | |||
*[[Extranodal NK-T-cell lymphoma|Extranodal NK/T-cell lymphoma]] is a rare disease in children and often it is associated with mosquito-bite [[hypersensitivity]] or other [[Epstein Barr virus|EBV]]-associated disease.<ref name="HarabuchiTakahara2019">{{cite journal|last1=Harabuchi|first1=Yasuaki|last2=Takahara|first2=Miki|last3=Kishibe|first3=Kan|last4=Nagato|first4=Toshihiro|last5=Kumai|first5=Takumi|title=Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type: Basic Science and Clinical Progress|journal=Frontiers in Pediatrics|volume=7|year=2019|issn=2296-2360|doi=10.3389/fped.2019.00141}}</ref> | |||
=== Race === | |||
*[[Natural killer cell|Natural Killer (NK) cell]] lymphoma is a rare disease. NK/T cell lymphoma, nasal type (NKTCL) and aggressive NK-cell leukemia (ANKCL) have a higher incidence in Asia, Central, and South America. | |||
* Nk cell lymphoma is usually associated with [[Epstein Barr virus|Epstein-Barr virus]] infection.<ref name="Lima2013">{{cite journal|last1=Lima|first1=Margarida|title=Aggressive mature natural killer cell neoplasms: from epidemiology to diagnosis|journal=Orphanet Journal of Rare Diseases|volume=8|issue=1|year=2013|pages=95|issn=1750-1172|doi=10.1186/1750-1172-8-95}}</ref> | |||
=== Gender === | |||
*[[Extranodal NK-T-cell lymphoma|Extranodal NK/T-cell lymphoma]] shows male preponderance.<ref name="WangGong2017">{{cite journal|last1=Wang|first1=Xiaotian|last2=Gong|first2=Zimu|last3=Li|first3=Shawn Xiang|last4=Yan|first4=Wei|last5=Song|first5=Yongsheng|title=Extranodal nasal-type natural killer/T-cell lymphoma with penile involvement: a case report and review of the literature|journal=BMC Urology|volume=17|issue=1|year=2017|issn=1471-2490|doi=10.1186/s12894-017-0273-8}}</ref> | |||
=== Region === | |||
*[[Extranodal NK-T-cell lymphoma|Extranodal NK T cell lymphoma]], nasal type (NNKTL) consist 3000-10000 out of 100000 cases of [[non-Hodgkin lymphoma]] in Asia and South America and less than 1000 in 10000 patient in western countries. | |||
*It is estimated the incidence of NNKTL is higher in Asia by 10-folds.<ref name="HaverkosPan2016">{{cite journal|last1=Haverkos|first1=Bradley M.|last2=Pan|first2=Zenggang|last3=Gru|first3=Alejandro A.|last4=Freud|first4=Aharon G.|last5=Rabinovitch|first5=Rachel|last6=Xu-Welliver|first6=Meng|last7=Otto|first7=Brad|last8=Barrionuevo|first8=Carlos|last9=Baiocchi|first9=Robert A.|last10=Rochford|first10=Rosemary|last11=Porcu|first11=Pierluigi|title=Extranodal NK/T Cell Lymphoma, Nasal Type (ENKTL-NT): An Update on Epidemiology, Clinical Presentation, and Natural History in North American and European Cases|journal=Current Hematologic Malignancy Reports|volume=11|issue=6|year=2016|pages=514–527|issn=1558-8211|doi=10.1007/s11899-016-0355-9}}</ref> | |||
== References == | |||
<references /> | |||
Latest revision as of 13:27, 28 October 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ramyar Ghandriz MD[2] Sowminya Arikapudi, M.B,B.S. [3]
Overview
NK cell lymphoma shows a poor prognosis because of rapid local progression and distant metastasis.The median age of onset is approximately 50 years and it is common in elderly. extranodal NK/T-cell lymphoma is a rare disease in children and often it is associated with mosquito-bite hypersensitivity or other EBV-associated disease.Natural Killer (NK) cell lymphoma is a rare disease. extranodal NK/T cell lymphoma, nasal type (NKTCL) and aggressive NK-cell leukemia (ANKCL) have a higher incidence in Asia, Central, and South America.NK T cell lymphoma, nasal type (NNKTL) consist 3000-10000 out of 100000 cases of non-Hodgkin lymphoma in Asia and South America and less than 1000 in 10000 patient in western countries
Epidemiology and Demographics
Mortality rate
- NK cell lymphoma shows a poor prognosis because of rapid local progression and distant metastasis.[1]
Age
- The median age of onset is approximately 50 years and it is common in the elderly.
- Extranodal NK/T-cell lymphoma is a rare disease in children and often it is associated with mosquito-bite hypersensitivity or other EBV-associated disease.[2]
Race
- Natural Killer (NK) cell lymphoma is a rare disease. NK/T cell lymphoma, nasal type (NKTCL) and aggressive NK-cell leukemia (ANKCL) have a higher incidence in Asia, Central, and South America.
- Nk cell lymphoma is usually associated with Epstein-Barr virus infection.[3]
Gender
- Extranodal NK/T-cell lymphoma shows male preponderance.[4]
Region
- Extranodal NK T cell lymphoma, nasal type (NNKTL) consist 3000-10000 out of 100000 cases of non-Hodgkin lymphoma in Asia and South America and less than 1000 in 10000 patient in western countries.
- It is estimated the incidence of NNKTL is higher in Asia by 10-folds.[5]
References
- ↑ Jaffe, Elaine S; Nicolae, Alina; Pittaluga, Stefania (2013). "Peripheral T-cell and NK-cell lymphomas in the WHO classification: pearls and pitfalls". Modern Pathology. 26 (S1): S71–S87. doi:10.1038/modpathol.2012.181. ISSN 0893-3952.
- ↑ Harabuchi, Yasuaki; Takahara, Miki; Kishibe, Kan; Nagato, Toshihiro; Kumai, Takumi (2019). "Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type: Basic Science and Clinical Progress". Frontiers in Pediatrics. 7. doi:10.3389/fped.2019.00141. ISSN 2296-2360.
- ↑ Lima, Margarida (2013). "Aggressive mature natural killer cell neoplasms: from epidemiology to diagnosis". Orphanet Journal of Rare Diseases. 8 (1): 95. doi:10.1186/1750-1172-8-95. ISSN 1750-1172.
- ↑ Wang, Xiaotian; Gong, Zimu; Li, Shawn Xiang; Yan, Wei; Song, Yongsheng (2017). "Extranodal nasal-type natural killer/T-cell lymphoma with penile involvement: a case report and review of the literature". BMC Urology. 17 (1). doi:10.1186/s12894-017-0273-8. ISSN 1471-2490.
- ↑ Haverkos, Bradley M.; Pan, Zenggang; Gru, Alejandro A.; Freud, Aharon G.; Rabinovitch, Rachel; Xu-Welliver, Meng; Otto, Brad; Barrionuevo, Carlos; Baiocchi, Robert A.; Rochford, Rosemary; Porcu, Pierluigi (2016). "Extranodal NK/T Cell Lymphoma, Nasal Type (ENKTL-NT): An Update on Epidemiology, Clinical Presentation, and Natural History in North American and European Cases". Current Hematologic Malignancy Reports. 11 (6): 514–527. doi:10.1007/s11899-016-0355-9. ISSN 1558-8211.