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{{CMG}}; {{AE}} {{S.M.}}
{{CMG}}; {{AE}} {{S.M.}}


*These include:<ref name="pmid12146044">{{cite journal| author=Zee SY, Wang Q, Jones CM, Abadi MA| title=Fine needle aspiration cytology of dermatofibrosarcoma protuberans presenting as a breast mass. A case report. | journal=Acta Cytol | year= 2002 | volume= 46 | issue= 4 | pages= 741-3 | pmid=12146044 | doi=10.1159/000326988 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12146044 }} </ref><ref name="pmid10579001">{{cite journal| author=Filipowicz EA, Ventura KC, Pou AM, Logrono R| title=FNAC in the diagnosis of recurrent dermatofibrosarcoma protuberans of the forehead. A case report. | journal=Acta Cytol | year= 1999 | volume= 43 | issue= 6 | pages= 1177-80 | pmid=10579001 | doi=10.1159/000331376 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10579001  }} </ref>
 
**FNAC <ref name="pmid12478683">{{cite journal| author=Domanski HA, Gustafson P| title=Cytologic features of primary, recurrent, and metastatic dermatofibrosarcoma protuberans. | journal=Cancer | year= 2002 | volume= 96 | issue= 6 | pages= 351-61 | pmid=12478683 | doi=10.1002/cncr.10760 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12478683  }} </ref><ref name="pmid15830369">{{cite journal| author=Domanski HA| title=FNA diagnosis of dermatofibrosarcoma protuberans. | journal=Diagn Cytopathol | year= 2005 | volume= 32 | issue= 5 | pages= 299-302 | pmid=15830369 | doi=10.1002/dc.20238 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15830369  }} </ref><ref name="pmid11176051">{{cite journal| author=Zamecnik M| title=Fibrosarcomatous dermatofibrosarcoma protuberans with giant rosettes. | journal=Am J Dermatopathol | year= 2001 | volume= 23 | issue= 1 | pages= 41-5 | pmid=11176051 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11176051  }} </ref><ref name="pmid15048962">{{cite journal| author=Klijanienko J, Caillaud JM, Lagacé R| title=Fine-needle aspiration of primary and recurrent dermatofibrosarcoma protuberans. | journal=Diagn Cytopathol | year= 2004 | volume= 30 | issue= 4 | pages= 261-5 | pmid=15048962 | doi=10.1002/dc.20024 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15048962  }} </ref>
 
**Biopsy
<ref name="pmid27261907">{{cite journal| author=Mao Y, Yang D, He J, Krasna MJ| title=Epidemiology of Lung Cancer. | journal=Surg Oncol Clin N Am | year= 2016 | volume= 25 | issue= 3 | pages= 439-45 | pmid=27261907 | doi=10.1016/j.soc.2016.02.001 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27261907 }} </ref>
**Immunohistochemistry
 
***CD34 staining <ref name="pmid9700370">{{cite journal| author=Harvell JD, Kilpatrick SE, White WL| title=Histogenetic relations between giant cell fibroblastoma and dermatofibrosarcoma protuberans. CD34 staining showing the spectrum and a simulator. | journal=Am J Dermatopathol | year= 1998 | volume= 20 | issue= 4 | pages= 339-45 | pmid=9700370 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9700370  }} </ref><ref name="pmid20061935">{{cite journal| author=Kutzner H, Mentzel T, Palmedo G, Hantschke M, Rütten A, Paredes BE et al.| title=Plaque-like CD34-positive dermal fibroma ("medallion-like dermal dendrocyte hamartoma"): clinicopathologic, immunohistochemical, and molecular analysis of 5 cases emphasizing its distinction from superficial, plaque-like dermatofibrosarcoma protuberans. | journal=Am J Surg Pathol | year= 2010 | volume= 34 | issue= 2 | pages= 190-201 | pmid=20061935 | doi=10.1097/PAS.0b013e3181c7cf11 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20061935  }} </ref>
[[File:Atypical Bcell gif.gif|thumb|200px|none|High-power field of peripheral blood smear revealing a large, atypical B cell with mild cytoplasmic expansion, coarse chromatin, multiple distinct nucleoli and peripheral vacuolation.[https://openi.nlm.nih.gov/detailedresult.php?img=PMC2944189_1752-1947-4-300-2&query=waldenstrom+macroglobulinaemia&it=xg&req=4&npos=17 Source: Charakidis M. et al, Department of Haematology-Oncology, Royal Hobart Hospital, Tasmania, 7000, Australia.]]]
**CT scan
 
{|
 
|
{|  
[[Image:Dermatofibrosarcoma-protuberans-001.jpg|thumb|200px|none|CT image demonstrating a dermatofibrosarcoma protuberans in the right groin]]
|+'''Classification of Waldenstrom macroglobulinemia (WM) and Related Disorders'''
|
! style="background:#4479BA; color: #FFFFFF;" align="center" + |Criteria
|}
! style="background:#4479BA; color: #FFFFFF;" align="center" + |Symptomatic WM
! style="background:#4479BA; color: #FFFFFF;" align="center" + |Asymptomatic WM
! style="background:#4479BA; color: #FFFFFF;" align="center" + |IgM-Related Disorders
! style="background:#4479BA; color: #FFFFFF;" align="center" + |MGUS
|-
! align="center" style="background:#DCDCDC;" + |IgM monoclonal protein
| style="background:#F5F5F5;" align="center" + | +
| style="background:#F5F5F5;" align="center" + | +
| style="background:#F5F5F5;" align="center" + | +
| style="background:#F5F5F5;" align="center" + | +
|-
! align="center" style="background:#DCDCDC;" + |Bone marrow infiltration
| style="background:#F5F5F5;" align="center" + | +
| style="background:#F5F5F5;" align="center" + | +
| style="background:#F5F5F5;" align="center" + | -
| style="background:#F5F5F5;" align="center" + | -
|-
! align="center" style="background:#DCDCDC;" + |Symptoms attributable to IgM
| style="background:#F5F5F5;" align="center" + | +
| style="background:#F5F5F5;" align="center" + | -
| style="background:#F5F5F5;" align="center" + | +
| style="background:#F5F5F5;" align="center" + | -
|-
! align="center" style="background:#DCDCDC;" + |Symptoms attributable to tumor infiltration
| style="background:#F5F5F5;" align="center" + | +
| style="background:#F5F5F5;" align="center" + | -
| style="background:#F5F5F5;" align="center" + | -
| style="background:#F5F5F5;" align="center" + | -
|}<br />
 
 
 
 
 
==Reference==
{{Reflist|2}}

Latest revision as of 18:18, 11 December 2020


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2]


[1]

High-power field of peripheral blood smear revealing a large, atypical B cell with mild cytoplasmic expansion, coarse chromatin, multiple distinct nucleoli and peripheral vacuolation.Source: Charakidis M. et al, Department of Haematology-Oncology, Royal Hobart Hospital, Tasmania, 7000, Australia.


Classification of Waldenstrom macroglobulinemia (WM) and Related Disorders
Criteria Symptomatic WM Asymptomatic WM IgM-Related Disorders MGUS
IgM monoclonal protein + + + +
Bone marrow infiltration + + - -
Symptoms attributable to IgM + - + -
Symptoms attributable to tumor infiltration + - - -




Reference

  1. ↑ Mao Y, Yang D, He J, Krasna MJ (2016). "Epidemiology of Lung Cancer". Surg Oncol Clin N Am. 25 (3): 439–45. doi:10.1016/j.soc.2016.02.001. PMID 27261907.
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