Medullary thyroid cancer classification: Difference between revisions
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==Overview== | ==Overview== | ||
Medullary thyroid cancer may be [[classification|classified]] according to the mode of occurrence into 2 groups: | Medullary thyroid cancer may be [[classification|classified]] according to the mode of occurrence into 2 groups: sporadic medullary thyroid cancer and [[inherited]] medullary thyroid cancer. | ||
==Classification== | ==Classification== | ||
* Medullary thyroid cancer may be [[classification|classified]] according to the mode of occurrence into 2 groups: sporadic medullary thyroid cancer and inherited medullary thyroid cancer. | * Medullary thyroid cancer may be [[classification|classified]] according to the mode of occurrence into 2 groups: sporadic medullary thyroid cancer and [[inherited]] medullary thyroid cancer. | ||
* Sporadic medullary thyroid cancer<ref>Thyroid Cancer Cancer.gov | * Sporadic medullary thyroid cancer<ref>Thyroid Cancer Cancer.gov | ||
(2015). http://www.cancer.gov/types/thyroid/hp/thyroid-treatment-pdq#link/stoc_h2_2- Accessed on October, 29 2015</ref> | (2015). http://www.cancer.gov/types/thyroid/hp/thyroid-treatment-pdq#link/stoc_h2_2- Accessed on October, 29 2015</ref><ref name="RaueFrank-Raue2015">{{cite journal|last1=Raue|first1=Friedhelm|last2=Frank-Raue|first2=Karin|title=Epidemiology and Clinical Presentation of Medullary Thyroid Carcinoma|volume=204|year=2015|pages=61–90|issn=0080-0015|doi=10.1007/978-3-319-22542-5_3}}</ref> | ||
:* Sporadic medullary thyroid cancer (75% of the cases) | :* Sporadic medullary thyroid cancer (75% of the cases) | ||
:* Inherited medullary thyroid cancer (25% of the cases) | :* Inherited medullary thyroid cancer (25% of the cases) | ||
:** MEN2A (23%) | :**[[Multiple endocrine neoplasia type 2A|MEN2A]] (23%) | ||
:** MEN2B (2%) | :**[[Multiple endocrine neoplasia type 2B|MEN2B]] (2%) | ||
:** Familial medullary thyroid cancer (FMTC)(rare) | :**[[Familial]] medullary thyroid cancer (FMTC)(rare) | ||
* Medullary thyroid cancer may be [[classification|classified]] according to [[histologic]] variants into:<ref>{{cite book | last = DeLellis | first = Ronald | title = Pathology and genetics of tumours of endocrine organs | publisher = IARC Press | location = Lyon | year = 2004 | isbn = 92-832-2416-7 }}</ref> | * Medullary thyroid cancer may be [[classification|classified]] according to [[histologic]] variants into:<ref>{{cite book | last = DeLellis | first = Ronald | title = Pathology and genetics of tumours of endocrine organs | publisher = IARC Press | location = Lyon | year = 2004 | isbn = 92-832-2416-7 }}</ref> | ||
** Papillary or pseudopapillary due to the presence of papillary structures or artifactual structures resembling papillae. | ** Papillary or pseudopapillary due to the presence of papillary structures or artifactual structures resembling papillae. |
Latest revision as of 15:24, 29 August 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Medullary thyroid cancer may be classified according to the mode of occurrence into 2 groups: sporadic medullary thyroid cancer and inherited medullary thyroid cancer.
Classification
- Medullary thyroid cancer may be classified according to the mode of occurrence into 2 groups: sporadic medullary thyroid cancer and inherited medullary thyroid cancer.
- Sporadic medullary thyroid cancer[1][2]
- Medullary thyroid cancer may be classified according to histologic variants into:[3]
- Papillary or pseudopapillary due to the presence of papillary structures or artifactual structures resembling papillae.
- Glandular
- Giant cells
- Spindle cell
- Small cell and Neuroblastoma-like
- Paraganglioma-like
- Onchocytic cell
- Clear cell
- Angiosarcoma-like
- Squamous cell
- Melanin-producing
- Amphicrine
Reference
- ↑ Thyroid Cancer Cancer.gov (2015). http://www.cancer.gov/types/thyroid/hp/thyroid-treatment-pdq#link/stoc_h2_2- Accessed on October, 29 2015
- ↑ Raue, Friedhelm; Frank-Raue, Karin (2015). "Epidemiology and Clinical Presentation of Medullary Thyroid Carcinoma". 204: 61–90. doi:10.1007/978-3-319-22542-5_3. ISSN 0080-0015.
- ↑ DeLellis, Ronald (2004). Pathology and genetics of tumours of endocrine organs. Lyon: IARC Press. ISBN 92-832-2416-7.