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| {{CMG}}; {{AE}} {{Fs}} | | {{CMG}}; {{AE}} {{Fs}} |
| ==Overview== | | ==Overview== |
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| | There is no established system for the [[classification]] of tetralogy of Fallot. |
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| ==Classification== | | ==Classification== |
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| [Disease name] may be classified according to [classification method] into [number] subtypes/groups: | | There is no established system for the [[classification]] of tetralogy of Fallot. |
| *[Group1]
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| *[Group2]
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| *[Group3]
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| *[Group4]
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| {|
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| ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Subtypes
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| ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Explanation
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| ! style="background: #DCDCDC; text-align: center;" |Acute Motor Axonal Neuropathy (AMAN)
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| | style="background: #F5F5F5;" |
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| * The most common type (85-90%).
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| * Prior infection can trigger it.
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| * [[Autoimmune disorder]].
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| * The target is [[schwann cell]] surface membrane or the [[myelin]].
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| * Causes [[demyelination]].
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| * In electrodiagnostic tests we can see slowing of nerve conduction.
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| * In pathology we can see [[Lymphocyte|lymphocytic]] infiltration of peripheral nerves and [[macrophage]] invasion of [[myelin sheath]] and [[Schwann cell|schwann cells]].
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| ! style="background: #DCDCDC; text-align: center;" |Acute Motor Axonal Neuropathy (AMAN)
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| | style="background: #F5F5F5;" |
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| * It’s common among Chinese and Japanese people.
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| * It can be triggered by C. jejuni.
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| * It is associated with anti[[ganglioside]] [[antibodies]].
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| * [[Autoimmunity|Autoimmune]] disorder.
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| * Target is [[Axon|axonal]] membrane.
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| * Causes [[Axon|axonal]] degeneration in [[Motor neuron|motor neurons]].
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| * In electrodiagnostic study we can see reduction of compound muscle [[action potential]].
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| ! style="background: #DCDCDC; text-align: center;" |Acute motor and sensory axonal neuropathy
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| | style="background: #F5F5F5;" |
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| * The incidence rate is under 10%.
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| * Causes [[Axon|axonal]] [[degeneration]].
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| * It is similar with [[Acute motor axonal neuropathy|AMAN]] but involves both motor and sensory [[Axon|axons]].
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| ! style="background: #DCDCDC; text-align: center;" |Miller Fisher syndrome
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| | style="background: #F5F5F5;" |
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| * Causes a clinical triad: [[ophthalmoplegia]], [[ataxia]] and [[areflexia]].
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| * Associated with [[ganglioside]] GQ1b [[antibody]].
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| |}
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