Pulmonary atresia medical therapy: Difference between revisions
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{{CMG}}; '''Associate Editor(s)-In-Chief:''' [[Priyamvada Singh|Priyamvada Singh, M.B.B.S.]] [mailto:psingh13579@gmail.com], {{CZ}}; '''Assistant Editor(s)-In-Chief:''' [[Kristin Feeney|Kristin Feeney, B.S.]] [mailto:kfeeney@elon.edu] | {{CMG}}; '''Associate Editor(s)-In-Chief:''' [[Priyamvada Singh|Priyamvada Singh, M.B.B.S.]] [mailto:psingh13579@gmail.com], {{CZ}}; '''Assistant Editor(s)-In-Chief:''' [[Kristin Feeney|Kristin Feeney, B.S.]] [mailto:kfeeney@elon.edu] | ||
==Medical Therapy== | ===Medical Therapy=== | ||
* Medical therapy in | * Medical therapy in newborns with Pulmonary atresia serves only as a bridge to surgical treatment. It is temporarily and definitive treatment is only surgical. | ||
* It is targeted to keep the ductus arteriosus open that otherwise will close in 48 hr. | * It is targeted to keep the ductus arteriosus open that otherwise will close in 48 hr. An IV medication called prostaglandin E1 is used to keep the ductus arteriosus open and gives time while the newborn will be prepared for the definitive treatment. Blood circulates from the aorta to the pulmonary artery via this ductus and gets oxygenated in the lungs. | ||
* | * Another short term strategy is keeping the opening between the right and left atrium patent ( foramen ovale ). This process is called "Balloon atrial septostomy" done via Cardiac Catheterization. A guided wire with the tip of the balloon on it is inserted via vein and advanced to the right side of the heart. reaching the foramen ovale. The balloon tip is inflated and adjusted at the opening and the wire is removed This opening will shunt the blood from the right atrium to the left, to the aorta, and via ductus arterosus to the pulmonary artery and then to the lungs for proper oxygenation. | ||
*It should be kept in mind these | * It should be kept in mind these procedures ONLY are the short term management and eventually newborn will need surgery. <ref>{{cite web |url=https://www.cdc.gov/ncbddd/heartdefects/pulmonaryatresia.html |title=Congenital Heart Defects - Facts about Pulmonary Atresia | CDC |format= |work= |accessdate=}}</ref> <ref> {{cite web |url=http://www.heart.org/idc/groups/heart-public/@wcm/@hcm/documents/downloadable/ucm_307665.pdf |title=www.heart.org |format= |work= |accessdate=}} </ref> <ref>{{cite web |url=https://www.nhlbi.nih.gov/health-topics/congenital-heart-defects |title=Congenital Heart Defects | National Heart, Lung, and Blood Institute (NHLBI) |format= |work= |accessdate=}}</ref> | ||
'''Surgical:''' [[Pulmonary atresia surgery|Surgery]] | |||
[[Pulmonary atresia primary prevention|Primary Prevention]] | [[Pulmonary atresia secondary prevention|Secondary Prevention]] | [[Pulmonary atresia cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Pulmonary atresia future or investigational therapies|Future or Investigational Therapies]] | |||
==References== | ==References== | ||
Latest revision as of 03:57, 6 July 2020
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Pulmonary atresia Microchapters |
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Diagnosis |
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Treatment |
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Pulmonary atresia medical therapy On the Web |
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American Roentgen Ray Society Images of Pulmonary atresia medical therapy |
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Risk calculators and risk factors for Pulmonary atresia medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [2], Cafer Zorkun, M.D., Ph.D. [3]; Assistant Editor(s)-In-Chief: Kristin Feeney, B.S. [4]
Medical Therapy
- Medical therapy in newborns with Pulmonary atresia serves only as a bridge to surgical treatment. It is temporarily and definitive treatment is only surgical.
- It is targeted to keep the ductus arteriosus open that otherwise will close in 48 hr. An IV medication called prostaglandin E1 is used to keep the ductus arteriosus open and gives time while the newborn will be prepared for the definitive treatment. Blood circulates from the aorta to the pulmonary artery via this ductus and gets oxygenated in the lungs.
- Another short term strategy is keeping the opening between the right and left atrium patent ( foramen ovale ). This process is called "Balloon atrial septostomy" done via Cardiac Catheterization. A guided wire with the tip of the balloon on it is inserted via vein and advanced to the right side of the heart. reaching the foramen ovale. The balloon tip is inflated and adjusted at the opening and the wire is removed This opening will shunt the blood from the right atrium to the left, to the aorta, and via ductus arterosus to the pulmonary artery and then to the lungs for proper oxygenation.
- It should be kept in mind these procedures ONLY are the short term management and eventually newborn will need surgery. [1] [2] [3]
Surgical: Surgery
Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies