Bronchogenic cyst overview: Difference between revisions

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Bronchogenic [[cyst]] is a rare [[benign]] [[congenital malformation]] of the [[respiratory tract|tracheobronchial tree]] derived from the ventral aspect of the [[foregut]]. It most frequently occurs in the middle mediastinum, in the early stages of [[gestation]] or in the lungs, at the later stages of gestation. Atypical locations may be explained by its embryologic origin.  
Bronchogenic [[cyst]] is a rare [[benign]] [[congenital malformation]] of the [[respiratory tract|tracheobronchial tree]] derived from the ventral aspect of the [[foregut]]. It most frequently occurs in the middle mediastinum, in the early stages of [[gestation]] or in the lungs, at the later stages of gestation. Atypical locations may be explained by its embryologic origin.  
Patients with bronchogenic [[cyst]] may be asymptomatic or present with [[respiratory distress]], increasing [[stridor]],  feeding difficulties, [[chest pain]], [[cough]], progressive [[dysphagia]], [[odynophagia]], purulent sputum, [[dyspnea]], [[anorexia]] and/or[[ weight loss]].
Patients with bronchogenic [[cyst]] may be asymptomatic or present with [[respiratory distress]], increasing [[stridor]],  feeding difficulties, [[chest pain]], [[cough]], progressive [[dysphagia]], [[odynophagia]], purulent sputum, [[dyspnea]], [[anorexia]] and/or[[ weight loss]].
Radiologic findings are useful to differentiate bronchogenic [[cysts]] from other [[cysts]] but may they not always confirm the diagnosis. Diagnosis is confirmed by surgical excision, which is curative, and histological findings of ciliated [[columnar epithelial]] lining of the [[cyst]].
Radiologic findings are useful to differentiate bronchogenic [[cysts]] from other [[cysts]] but they may not always confirm the diagnosis. Diagnosis is confirmed by surgical excision, which is curative, and histological findings of ciliated [[columnar epithelial]] lining of the [[cyst]].
 
==Historical Perspective==
==Historical Perspective==
There is limited information about the historical perspective of bronchogenic [[cyst]].
There is limited information about the historical perspective of bronchogenic [[cyst]].
==Classification==
==Classification==
Bronchogenic [[cyst]] can be classified based on location; pulmonary and extrapulmonary.<ref name="pmid17859095">{{cite journal| author=Maier HC| title=Bronchiogenic Cysts of the Mediastinum. | journal=Ann Surg | year= 1948 | volume= 127 | issue= 3 | pages= 476-502 | pmid=17859095 | doi=10.1097/00000658-194803000-00010 | pmc=1513836 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17859095  }} </ref><ref name="pmid12809250">{{cite journal| author=Sarper A, Ayten A, Golbasi I, Demircan A, Isin E| title=Bronchogenic cyst. | journal=Tex Heart Inst J | year= 2003 | volume= 30 | issue= 2 | pages= 105-8 | pmid=12809250 | doi= | pmc=161894 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12809250  }} </ref>
Bronchogenic [[cyst]] can be classified based on location; pulmonary and extrapulmonary.
 
==Pathophysiology==
==Pathophysiology==
It is thought that bronchogenic [[cyst]] is the result of abnormal budding of the ventral <ref name="pmid26986156">{{cite journal| author=Han C, Lin R, Yu J, Zhang Q, Zhang Y, Liu J | display-authors=etal| title=A Case Report of Esophageal Bronchogenic Cyst and Review of the Literature With an Emphasis on Endoscopic Ultrasonography Appearance. | journal=Medicine (Baltimore) | year= 2016 | volume= 95 | issue= 11 | pages= e3111 | pmid=26986156 | doi=10.1097/MD.0000000000003111 | pmc=4839937 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26986156  }} </ref> portion of the primitive [[foregut]]<ref name="pmid17859095">{{cite journal| author=Maier HC| title=Bronchiogenic Cysts of the Mediastinum. | journal=Ann Surg | year= 1948 | volume= 127 | issue= 3 | pages= 476-502 | pmid=17859095 | doi=10.1097/00000658-194803000-00010 | pmc=1513836 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17859095  }} </ref><ref name="pmid12809250">{{cite journal| author=Sarper A, Ayten A, Golbasi I, Demircan A, Isin E| title=Bronchogenic cyst. | journal=Tex Heart Inst J | year= 2003 | volume= 30 | issue= 2 | pages= 105-8 | pmid=12809250 | doi= | pmc=161894 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12809250  }} </ref><ref name="pmid19015445">{{cite journal| author=Teissier N, Elmaleh-Bergès M, Ferkdadji L, François M, Van den Abbeele T| title=Cervical bronchogenic cysts: usual and unusual clinical presentations. | journal=Arch Otolaryngol Head Neck Surg | year= 2008 | volume= 134 | issue= 11 | pages= 1165-9 | pmid=19015445 | doi=10.1001/archotol.134.11.1165 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19015445  }} </ref>destined to become the [[respiratory tract|tracheobronchial tree]]<ref name="pmid30725658">{{cite journal| author=| title=StatPearls | journal= | year= 2020 | volume=  | issue=  | pages=  | pmid=30725658 | doi= | pmc= | url= }} </ref> between days 26 - 40 of  [[gestation]].
It is thought that bronchogenic [[cyst]] is the result of abnormal budding of the ventral portion of the primitive [[foregut]] between days 26 - 40 of  [[gestation]].
 
==Causes==
==Causes==
The cause of bronchogenic cysts is undetermined.
The cause of bronchogenic cysts is undetermined.
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Differentiating bronchogenic [[cyst]] from [[Lung abscess physical examination|lung abcess]], [[Mediastinal mass differential diagnosis|thymic cyst]], and [[Mediastinal mass differential diagnosis|esophageal duplication cysts]].
Differentiating bronchogenic [[cyst]] from [[Lung abscess physical examination|lung abcess]], [[Mediastinal mass differential diagnosis|thymic cyst]], and [[Mediastinal mass differential diagnosis|esophageal duplication cysts]].
==Bronchogenic cyst epidemiology and demographics|Epidemiology and Demographics==
==Bronchogenic cyst epidemiology and demographics|Epidemiology and Demographics==
There is no racial predilection to bronchogenic [[cyst]]. Bronchogenic [[cyst]] is slightly more [[prevalence|prevalent]] in men and often remain undetected till the third or fourth decade of life.<ref name="pmid10554866">{{cite journal| author=Lardinois D, Gugger M, Ris HB| title=Bronchogenic cyst of the left lower lobe associated with severe hemoptysis. | journal=Eur J Cardiothorac Surg | year= 1999 | volume= 16 | issue= 3 | pages= 382-3 | pmid=10554866 | doi=10.1016/s1010-7940(99)00226-2 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10554866  }} </ref><ref name="pmid8902460">{{cite journal| author=Aktoğu S, Yuncu G, Halilçolar H, Ermete S, Buduneli T| title=Bronchogenic cysts: clinicopathological presentation and treatment. | journal=Eur Respir J | year= 1996 | volume= 9 | issue= 10 | pages= 2017-21 | pmid=8902460 | doi=10.1183/09031936.96.09102017 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8902460  }} </ref>
There is no racial predilection to bronchogenic [[cyst]]. Bronchogenic [[cyst]] is slightly more [[prevalence|prevalent]] in men and often remain undetected until the third or fourth decade of life.
 
==Risk factors==
==Risk factors==
There are no established risk factors for bronchogenic [[cyst]].
There are no established risk factors for bronchogenic [[cyst]].
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The symptoms of bronchogenic [[cyst]] usually develop in the third to fourth decade of life and start with symptoms such as
The symptoms of bronchogenic [[cyst]] usually develop in the third to fourth decade of life and start with symptoms such as
*[[Dyspnea]]<ref name="pmid12809250">{{cite journal| author=Sarper A, Ayten A, Golbasi I, Demircan A, Isin E| title=Bronchogenic cyst. | journal=Tex Heart Inst J | year= 2003 | volume= 30 | issue= 2 | pages= 105-8 | pmid=12809250 | doi= | pmc=161894 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12809250  }} </ref><ref name="pmid29895549">{{cite journal| author=Mesland JB, Gérard L, Van Caenegem O, Castanares-Zapatero D| title=Bronchogenic cyst infection presenting as pleuropericarditis. | journal=BMJ Case Rep | year= 2018 | volume= 2018 | issue=  | pages=  | pmid=29895549 | doi=10.1136/bcr-2018-225081 | pmc=6011476 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29895549  }} </ref><ref name="pmid30098916">{{cite journal| author=Yildiz H, Reichwein R, Poncelet A, Lacroix V, D'abadie P, Ghaye B | display-authors=etal| title=An unusual case of cardiac tamponade: Bronchogenic cyst infection due to Salmonella bredeney. | journal=J Infect Chemother | year= 2019 | volume= 25 | issue= 2 | pages= 151-153 | pmid=30098916 | doi=10.1016/j.jiac.2018.07.012 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30098916  }} </ref><ref name="pmid26234845">{{cite journal| author=Olsen M, Mitchell TA, Percival TJ, Helsel BS| title=Interatrial Bronchogenic Cyst Resection. | journal=Ann Thorac Surg | year= 2015 | volume= 100 | issue= 2 | pages= 709-11 | pmid=26234845 | doi=10.1016/j.athoracsur.2014.10.025 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26234845  }} </ref>
*[[Dyspnea]]
*Chronic dry [[cough]]<ref name="pmid12809250">{{cite journal| author=Sarper A, Ayten A, Golbasi I, Demircan A, Isin E| title=Bronchogenic cyst. | journal=Tex Heart Inst J | year= 2003 | volume= 30 | issue= 2 | pages= 105-8 | pmid=12809250 | doi= | pmc=161894 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12809250  }} </ref><ref name="pmid29895549">{{cite journal| author=Mesland JB, Gérard L, Van Caenegem O, Castanares-Zapatero D| title=Bronchogenic cyst infection presenting as pleuropericarditis. | journal=BMJ Case Rep | year= 2018 | volume= 2018 | issue=  | pages=  | pmid=29895549 | doi=10.1136/bcr-2018-225081 | pmc=6011476 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29895549  }} </ref><ref name="pmid26234845">{{cite journal| author=Olsen M, Mitchell TA, Percival TJ, Helsel BS| title=Interatrial Bronchogenic Cyst Resection. | journal=Ann Thorac Surg | year= 2015 | volume= 100 | issue= 2 | pages= 709-11 | pmid=26234845 | doi=10.1016/j.athoracsur.2014.10.025 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26234845  }} </ref>
*Chronic dry [[cough]]
*[[Rhinitis]]<ref name="pmid28696968">{{cite journal| author=DiBardino DM, Brenner K| title=Bronchogenic Cyst Abscess. | journal=J Bronchology Interv Pulmonol | year= 2017 | volume= 24 | issue= 3 | pages= 31-32 | pmid=28696968 | doi=10.1097/LBR.0000000000000375 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28696968  }} </ref>
*[[Rhinitis]]
*[[chest pain|Chest discomfort/pain]]<ref name="pmid12809250">{{cite journal| author=Sarper A, Ayten A, Golbasi I, Demircan A, Isin E| title=Bronchogenic cyst. | journal=Tex Heart Inst J | year= 2003 | volume= 30 | issue= 2 | pages= 105-8 | pmid=12809250 | doi= | pmc=161894 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12809250  }} </ref><ref name="pmid27068723">{{cite journal| author=Chumakova M, Morris-Stiff G, Khachaturov V, Ibrahim S| title=Bronchogenic cyst arising from the crus of the left hemidiaphragm. | journal=BMJ Case Rep | year= 2016 | volume= 2016 | issue=  | pages=  | pmid=27068723 | doi=10.1136/bcr-2015-213658 | pmc=4840741 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27068723  }} </ref><ref name="pmid29895549">{{cite journal| author=Mesland JB, Gérard L, Van Caenegem O, Castanares-Zapatero D| title=Bronchogenic cyst infection presenting as pleuropericarditis. | journal=BMJ Case Rep | year= 2018 | volume= 2018 | issue=  | pages=  | pmid=29895549 | doi=10.1136/bcr-2018-225081 | pmc=6011476 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29895549  }} </ref><ref name="pmid30098916">{{cite journal| author=Yildiz H, Reichwein R, Poncelet A, Lacroix V, D'abadie P, Ghaye B | display-authors=etal| title=An unusual case of cardiac tamponade: Bronchogenic cyst infection due to Salmonella bredeney. | journal=J Infect Chemother | year= 2019 | volume= 25 | issue= 2 | pages= 151-153 | pmid=30098916 | doi=10.1016/j.jiac.2018.07.012 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30098916  }} </ref>
*[[chest pain|Chest discomfort/pain]]
*[[Neck pain]]<ref name="pmid30702626">{{cite journal| author=Chen F, Marx S, Zhang C, Cao J, Yu Y, Chen D| title=Intramedullary bronchogenic cyst in the foramen magnum region accompanied with syringomyelia: A case report and literature review. | journal=Medicine (Baltimore) | year= 2019 | volume= 98 | issue= 5 | pages= e14353 | pmid=30702626 | doi=10.1097/MD.0000000000014353 | pmc=6380722 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30702626  }} </ref>
*[[Neck pain]]
*Flu-like symptoms and [[Fever]]<ref name="pmid12809250">{{cite journal| author=Sarper A, Ayten A, Golbasi I, Demircan A, Isin E| title=Bronchogenic cyst. | journal=Tex Heart Inst J | year= 2003 | volume= 30 | issue= 2 | pages= 105-8 | pmid=12809250 | doi= | pmc=161894 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12809250  }} </ref><ref name="pmid29895549">{{cite journal| author=Mesland JB, Gérard L, Van Caenegem O, Castanares-Zapatero D| title=Bronchogenic cyst infection presenting as pleuropericarditis. | journal=BMJ Case Rep | year= 2018 | volume= 2018 | issue=  | pages=  | pmid=29895549 | doi=10.1136/bcr-2018-225081 | pmc=6011476 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29895549  }} </ref><ref name="pmid30098916">{{cite journal| author=Yildiz H, Reichwein R, Poncelet A, Lacroix V, D'abadie P, Ghaye B | display-authors=etal| title=An unusual case of cardiac tamponade: Bronchogenic cyst infection due to Salmonella bredeney. | journal=J Infect Chemother | year= 2019 | volume= 25 | issue= 2 | pages= 151-153 | pmid=30098916 | doi=10.1016/j.jiac.2018.07.012 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30098916  }} </ref>
*Flu-like symptoms and [[Fever]]
*Purulent [[sputum]]<ref name="pmid12809250">{{cite journal| author=Sarper A, Ayten A, Golbasi I, Demircan A, Isin E| title=Bronchogenic cyst. | journal=Tex Heart Inst J | year= 2003 | volume= 30 | issue= 2 | pages= 105-8 | pmid=12809250 | doi= | pmc=161894 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12809250  }} </ref>
*Purulent [[sputum]]
*[[abdominal pain|Abdominal discomfort]]
*[[abdominal pain|Abdominal discomfort]]
*[[paralysis|Limb weakness]]
*[[paralysis|Limb weakness]]
*[[Paroxysmal supraventricular tachycardia]]<ref name="pmid26329634">{{cite journal| author=Mega S| title=[Anterior Mediastinal Bronchogenic Cyst Associated with paroxysmal supraventricular tachycardia ; Report of a Case]. | journal=Kyobu Geka | year= 2015 | volume= 68 | issue= 10 | pages= 871-3 | pmid=26329634 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26329634  }} </ref>
*[[Paroxysmal supraventricular tachycardia]]
*[[Atrioventricular block]]<ref name="pmid28139004">{{cite journal| author=Miwa E, Tani T, Okada Y, Furukawa Y| title=A rare cardiac tumor: Bronchogenic cyst of interatrial septum. | journal=Echocardiography | year= 2017 | volume= 34 | issue= 3 | pages= 474-475 | pmid=28139004 | doi=10.1111/echo.13445 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28139004  }} </ref>
*[[Atrioventricular block]]
*[[Amnesia|Memory impairment]]<ref name="pmid31348319">{{cite journal| author=Bian B, Yu M, Liu S, Li S, Wei Y, Zhang B| title=A suprasellar bronchogenic cyst: A case report. | journal=Medicine (Baltimore) | year= 2019 | volume= 98 | issue= 30 | pages= e16650 | pmid=31348319 | doi=10.1097/MD.0000000000016650 | pmc=6709100 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31348319  }} </ref>
*[[Amnesia|Memory impairment]]
*[[Asthenia]]<ref name="pmid31348319">{{cite journal| author=Bian B, Yu M, Liu S, Li S, Wei Y, Zhang B| title=A suprasellar bronchogenic cyst: A case report. | journal=Medicine (Baltimore) | year= 2019 | volume= 98 | issue= 30 | pages= e16650 | pmid=31348319 | doi=10.1097/MD.0000000000016650 | pmc=6709100 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31348319  }} </ref><ref name="pmid26097578">{{cite journal| author=Zou MX, Hu JR, Kang YJ, Li J, Lv GH, She XL| title=Bronchogenic cyst of the conus medullaris with spinal cord tethering: a case report and review of the literature. | journal=Int J Clin Exp Pathol | year= 2015 | volume= 8 | issue= 4 | pages= 3937-42 | pmid=26097578 | doi= | pmc=4466965 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26097578  }} </ref><ref name="pmid29390371">{{cite journal| author=Lee HD, Han SH, Park SB, Ko Y, Lee KH| title=An intradural extramedullary bronchogenic cyst in the thoracolumbar spine: A case report. | journal=Medicine (Baltimore) | year= 2017 | volume= 96 | issue= 50 | pages= e9263 | pmid=29390371 | doi=10.1097/MD.0000000000009263 | pmc=5815783 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29390371  }} </ref>
*[[Asthenia]]
*[[Seizure]] and [[loss of consciousness]]<ref name="pmid26969135">{{cite journal| author=Khawar M, Elmahrouk A, Chaikhouni A| title=Air embolism during air flight in a passenger with bronchogenic cyst. | journal=J Thorac Cardiovasc Surg | year= 2016 | volume= 152 | issue= 1 | pages= e1-2 | pmid=26969135 | doi=10.1016/j.jtcvs.2016.02.014 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26969135  }} </ref>
*[[Seizure]] and [[loss of consciousness]]
*[[Dizziness]]<ref name="pmid25780019">{{cite journal| author=Xu Q, Feng Y, Ye K, Zhou Y, Zhan R| title=Bronchogenic cyst in left anterior cranial fossa. | journal=Neurology | year= 2015 | volume= 84 | issue= 11 | pages= 1181-2 | pmid=25780019 | doi=10.1212/WNL.0000000000001368 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25780019  }} </ref>
*[[Dizziness]]
*Lower [[back pain]]<ref name="pmid26097578">{{cite journal| author=Zou MX, Hu JR, Kang YJ, Li J, Lv GH, She XL| title=Bronchogenic cyst of the conus medullaris with spinal cord tethering: a case report and review of the literature. | journal=Int J Clin Exp Pathol | year= 2015 | volume= 8 | issue= 4 | pages= 3937-42 | pmid=26097578 | doi= | pmc=4466965 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26097578  }} </ref>
*Lower [[back pain]]
*[[Urinary incontinence]]<ref name="pmid26097578">{{cite journal| author=Zou MX, Hu JR, Kang YJ, Li J, Lv GH, She XL| title=Bronchogenic cyst of the conus medullaris with spinal cord tethering: a case report and review of the literature. | journal=Int J Clin Exp Pathol | year= 2015 | volume= 8 | issue= 4 | pages= 3937-42 | pmid=26097578 | doi= | pmc=4466965 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26097578  }} </ref>
*[[Urinary incontinence]]


'''Complication'''
'''Complication'''


Common complications of bronchogenic [[cyst]] include
Common complications of bronchogenic [[cyst]] include
*[[Tracheal compression]]<ref name="pmid8651761">{{cite journal| author=Ribet ME, Copin MC, Gosselin BH| title=Bronchogenic cysts of the lung. | journal=Ann Thorac Surg | year= 1996 | volume= 61 | issue= 6 | pages= 1636-40 | pmid=8651761 | doi=10.1016/0003-4975(96)00172-5 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8651761  }} </ref><ref name="pmid8902460">{{cite journal| author=Aktoğu S, Yuncu G, Halilçolar H, Ermete S, Buduneli T| title=Bronchogenic cysts: clinicopathological presentation and treatment. | journal=Eur Respir J | year= 1996 | volume= 9 | issue= 10 | pages= 2017-21 | pmid=8902460 | doi=10.1183/09031936.96.09102017 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8902460  }} </ref>
*[[Tracheal compression]]
*Esophageal compression<ref name="pmid12809250">{{cite journal| author=Sarper A, Ayten A, Golbasi I, Demircan A, Isin E| title=Bronchogenic cyst. | journal=Tex Heart Inst J | year= 2003 | volume= 30 | issue= 2 | pages= 105-8 | pmid=12809250 | doi= | pmc=161894 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12809250  }} </ref>
*Esophageal compression
*[[Cough]]<ref name="pmid8651761">{{cite journal| author=Ribet ME, Copin MC, Gosselin BH| title=Bronchogenic cysts of the lung. | journal=Ann Thorac Surg | year= 1996 | volume= 61 | issue= 6 | pages= 1636-40 | pmid=8651761 | doi=10.1016/0003-4975(96)00172-5 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8651761  }} </ref>
*[[Cough]]
*[[Infection]]/[[abscess]]<ref name="pmid8651761">{{cite journal| author=Ribet ME, Copin MC, Gosselin BH| title=Bronchogenic cysts of the lung. | journal=Ann Thorac Surg | year= 1996 | volume= 61 | issue= 6 | pages= 1636-40 | pmid=8651761 | doi=10.1016/0003-4975(96)00172-5 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8651761  }} </ref><ref name="pmid19015445">{{cite journal| author=Teissier N, Elmaleh-Bergès M, Ferkdadji L, François M, Van den Abbeele T| title=Cervical bronchogenic cysts: usual and unusual clinical presentations. | journal=Arch Otolaryngol Head Neck Surg | year= 2008 | volume= 134 | issue= 11 | pages= 1165-9 | pmid=19015445 | doi=10.1001/archotol.134.11.1165 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19015445  }} </ref><ref name="pmid31462259">{{cite journal| author=Yang X, Zong Y, Zhao HY, Wu YD, Ji M| title=Complete excision of esophageal bronchogenic cyst by endoscopic submucosal tunnel dissection: a case presentation. | journal=BMC Gastroenterol | year= 2019 | volume= 19 | issue= 1 | pages= 155 | pmid=31462259 | doi=10.1186/s12876-019-1072-3 | pmc=6714396 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31462259  }} </ref><ref name="pmid28696968">{{cite journal| author=DiBardino DM, Brenner K| title=Bronchogenic Cyst Abscess. | journal=J Bronchology Interv Pulmonol | year= 2017 | volume= 24 | issue= 3 | pages= 31-32 | pmid=28696968 | doi=10.1097/LBR.0000000000000375 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28696968  }} </ref>
*[[Infection]]/[[abscess]]
*[[Hemoptysis]]<ref name="pmid12809250">{{cite journal| author=Sarper A, Ayten A, Golbasi I, Demircan A, Isin E| title=Bronchogenic cyst. | journal=Tex Heart Inst J | year= 2003 | volume= 30 | issue= 2 | pages= 105-8 | pmid=12809250 | doi= | pmc=161894 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12809250  }} </ref><ref name="pmid8651761">{{cite journal| author=Ribet ME, Copin MC, Gosselin BH| title=Bronchogenic cysts of the lung. | journal=Ann Thorac Surg | year= 1996 | volume= 61 | issue= 6 | pages= 1636-40 | pmid=8651761 | doi=10.1016/0003-4975(96)00172-5 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8651761  }} </ref>
*[[Hemoptysis]]
*[[Superior vena cava syndrome]]<ref name="pmid8902460">{{cite journal| author=Aktoğu S, Yuncu G, Halilçolar H, Ermete S, Buduneli T| title=Bronchogenic cysts: clinicopathological presentation and treatment. | journal=Eur Respir J | year= 1996 | volume= 9 | issue= 10 | pages= 2017-21 | pmid=8902460 | doi=10.1183/09031936.96.09102017 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8902460  }} </ref><ref name="pmid25750196">{{cite journal| author=Hayabuchi Y, Sakata M, Kagami S| title=Bronchogenic cyst compressing the pulmonary artery and the left atrium. | journal=Eur Heart J Cardiovasc Imaging | year= 2015 | volume= 16 | issue= 7 | pages= 746 | pmid=25750196 | doi=10.1093/ehjci/jev059 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25750196  }} </ref><ref name="pmid31008767">{{cite journal| author=Parsons C, Zhao CB, Huang J| title=Gigantic Pericardial Bronchogenic Cyst Compressing Superior Vena Cava and Coronary Artery. | journal=Anesthesiology | year= 2019 | volume= 131 | issue= 3 | pages= 667 | pmid=31008767 | doi=10.1097/ALN.0000000000002739 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31008767  }} </ref>
*[[Superior vena cava syndrome]]
*[[Pneumothorax]]<ref name="pmid12809250">{{cite journal| author=Sarper A, Ayten A, Golbasi I, Demircan A, Isin E| title=Bronchogenic cyst. | journal=Tex Heart Inst J | year= 2003 | volume= 30 | issue= 2 | pages= 105-8 | pmid=12809250 | doi= | pmc=161894 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12809250  }} </ref><ref name="pmid8902460">{{cite journal| author=Aktoğu S, Yuncu G, Halilçolar H, Ermete S, Buduneli T| title=Bronchogenic cysts: clinicopathological presentation and treatment. | journal=Eur Respir J | year= 1996 | volume= 9 | issue= 10 | pages= 2017-21 | pmid=8902460 | doi=10.1183/09031936.96.09102017 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8902460  }} </ref>
*[[Pneumothorax]]
*[[Pleurisy]]<ref name="pmid8902460">{{cite journal| author=Aktoğu S, Yuncu G, Halilçolar H, Ermete S, Buduneli T| title=Bronchogenic cysts: clinicopathological presentation and treatment. | journal=Eur Respir J | year= 1996 | volume= 9 | issue= 10 | pages= 2017-21 | pmid=8902460 | doi=10.1183/09031936.96.09102017 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8902460  }} </ref>
*[[Pleurisy]]
*[[Pneumonia]]<ref name="pmid12809250">{{cite journal| author=Sarper A, Ayten A, Golbasi I, Demircan A, Isin E| title=Bronchogenic cyst. | journal=Tex Heart Inst J | year= 2003 | volume= 30 | issue= 2 | pages= 105-8 | pmid=12809250 | doi= | pmc=161894 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12809250  }} </ref><ref name="pmid8902460">{{cite journal| author=Aktoğu S, Yuncu G, Halilçolar H, Ermete S, Buduneli T| title=Bronchogenic cysts: clinicopathological presentation and treatment. | journal=Eur Respir J | year= 1996 | volume= 9 | issue= 10 | pages= 2017-21 | pmid=8902460 | doi=10.1183/09031936.96.09102017 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8902460  }} </ref>
*[[Pneumonia]]
*[[Lymphangioma]]<ref name="pmid19015445">{{cite journal| author=Teissier N, Elmaleh-Bergès M, Ferkdadji L, François M, Van den Abbeele T| title=Cervical bronchogenic cysts: usual and unusual clinical presentations. | journal=Arch Otolaryngol Head Neck Surg | year= 2008 | volume= 134 | issue= 11 | pages= 1165-9 | pmid=19015445 | doi=10.1001/archotol.134.11.1165 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19015445  }} </ref>
*[[Lymphangioma]]
*[[bleeding|Haemorrhage]]<ref name="pmid19015445">{{cite journal| author=Teissier N, Elmaleh-Bergès M, Ferkdadji L, François M, Van den Abbeele T| title=Cervical bronchogenic cysts: usual and unusual clinical presentations. | journal=Arch Otolaryngol Head Neck Surg | year= 2008 | volume= 134 | issue= 11 | pages= 1165-9 | pmid=19015445 | doi=10.1001/archotol.134.11.1165 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19015445  }} </ref><ref name="pmid31462259">{{cite journal| author=Yang X, Zong Y, Zhao HY, Wu YD, Ji M| title=Complete excision of esophageal bronchogenic cyst by endoscopic submucosal tunnel dissection: a case presentation. | journal=BMC Gastroenterol | year= 2019 | volume= 19 | issue= 1 | pages= 155 | pmid=31462259 | doi=10.1186/s12876-019-1072-3 | pmc=6714396 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31462259  }} </ref>
*[[bleeding|Haemorrhage]]
*[[Neoplasia]](adenocarcinoma, mucoepidermoid carcinoma,  anaplastic carcinoma, and leiomyosarcoma)<ref name="pmid19015445">{{cite journal| author=Teissier N, Elmaleh-Bergès M, Ferkdadji L, François M, Van den Abbeele T| title=Cervical bronchogenic cysts: usual and unusual clinical presentations. | journal=Arch Otolaryngol Head Neck Surg | year= 2008 | volume= 134 | issue= 11 | pages= 1165-9 | pmid=19015445 | doi=10.1001/archotol.134.11.1165 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19015445  }} </ref><ref name="pmid17874358">{{cite journal| author=Chuang KH, Huang TW, Cheng YL, Chen JC, Tzao C, Chang H | display-authors=etal| title=Esophageal bronchogenic cyst: a rare entity. | journal=Z Gastroenterol | year= 2007 | volume= 45 | issue= 9 | pages= 958-60 | pmid=17874358 | doi=10.1055/s-2007-963069 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17874358  }} </ref><ref name="pmid26986156">{{cite journal| author=Han C, Lin R, Yu J, Zhang Q, Zhang Y, Liu J | display-authors=etal| title=A Case Report of Esophageal Bronchogenic Cyst and Review of the Literature With an Emphasis on Endoscopic Ultrasonography Appearance. | journal=Medicine (Baltimore) | year= 2016 | volume= 95 | issue= 11 | pages= e3111 | pmid=26986156 | doi=10.1097/MD.0000000000003111 | pmc=4839937 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26986156  }} </ref><ref name="pmid31462259">{{cite journal| author=Yang X, Zong Y, Zhao HY, Wu YD, Ji M| title=Complete excision of esophageal bronchogenic cyst by endoscopic submucosal tunnel dissection: a case presentation. | journal=BMC Gastroenterol | year= 2019 | volume= 19 | issue= 1 | pages= 155 | pmid=31462259 | doi=10.1186/s12876-019-1072-3 | pmc=6714396 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31462259  }} </ref>
*[[Neoplasia]](adenocarcinoma, mucoepidermoid carcinoma,  anaplastic carcinoma, and leiomyosarcoma)
*[[cyst|Rupture]]<ref name="pmid12809250">{{cite journal| author=Sarper A, Ayten A, Golbasi I, Demircan A, Isin E| title=Bronchogenic cyst. | journal=Tex Heart Inst J | year= 2003 | volume= 30 | issue= 2 | pages= 105-8 | pmid=12809250 | doi= | pmc=161894 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12809250  }} </ref><ref name="pmid17874358">{{cite journal| author=Chuang KH, Huang TW, Cheng YL, Chen JC, Tzao C, Chang H | display-authors=etal| title=Esophageal bronchogenic cyst: a rare entity. | journal=Z Gastroenterol | year= 2007 | volume= 45 | issue= 9 | pages= 958-60 | pmid=17874358 | doi=10.1055/s-2007-963069 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17874358  }} </ref><ref name="pmid31462259">{{cite journal| author=Yang X, Zong Y, Zhao HY, Wu YD, Ji M| title=Complete excision of esophageal bronchogenic cyst by endoscopic submucosal tunnel dissection: a case presentation. | journal=BMC Gastroenterol | year= 2019 | volume= 19 | issue= 1 | pages= 155 | pmid=31462259 | doi=10.1186/s12876-019-1072-3 | pmc=6714396 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31462259  }} </ref>
*[[cyst|Rupture]]
*[[Air embolism]]<ref name="pmid26969135">{{cite journal| author=Khawar M, Elmahrouk A, Chaikhouni A| title=Air embolism during air flight in a passenger with bronchogenic cyst. | journal=J Thorac Cardiovasc Surg | year= 2016 | volume= 152 | issue= 1 | pages= e1-2 | pmid=26969135 | doi=10.1016/j.jtcvs.2016.02.014 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26969135  }} </ref>
*[[Air embolism]]
*[[Cardiac tamponade]]<ref name="pmid30098916">{{cite journal| author=Yildiz H, Reichwein R, Poncelet A, Lacroix V, D'abadie P, Ghaye B | display-authors=etal| title=An unusual case of cardiac tamponade: Bronchogenic cyst infection due to Salmonella bredeney. | journal=J Infect Chemother | year= 2019 | volume= 25 | issue= 2 | pages= 151-153 | pmid=30098916 | doi=10.1016/j.jiac.2018.07.012 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30098916  }} </ref>
*[[Cardiac tamponade]]
*[[Ventricular septal defect]]<ref name="pmid29897508">{{cite journal| author=Blesneac C, Horvath E, Muntean I, Benedek T, Toganel R| title=Intracardiac bronchogenic cyst associated with ventricular septal defect: an extremely rare feature in children. | journal=Eur Heart J Cardiovasc Imaging | year= 2018 | volume= 19 | issue= 9 | pages= 1074 | pmid=29897508 | doi=10.1093/ehjci/jey078 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29897508  }} </ref>
*[[Ventricular septal defect]]
*[[syringomyelia]]<ref name="pmid30702626">{{cite journal| author=Chen F, Marx S, Zhang C, Cao J, Yu Y, Chen D| title=Intramedullary bronchogenic cyst in the foramen magnum region accompanied with syringomyelia: A case report and literature review. | journal=Medicine (Baltimore) | year= 2019 | volume= 98 | issue= 5 | pages= e14353 | pmid=30702626 | doi=10.1097/MD.0000000000014353 | pmc=6380722 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30702626  }} </ref>
*[[syringomyelia]]
'''Prognosis'''


'''Prognosis'''
[[Prognosis]] is generally good, a [[Morbidity & Mortality]] rate of 20% has been recorded in older patients treated for bronchogenic [[cyst]].


[[Prognosis]] is generally good,<ref name="pmid19015445">{{cite journal| author=Teissier N, Elmaleh-Bergès M, Ferkdadji L, François M, Van den Abbeele T| title=Cervical bronchogenic cysts: usual and unusual clinical presentations. | journal=Arch Otolaryngol Head Neck Surg | year= 2008 | volume= 134 | issue= 11 | pages= 1165-9 | pmid=19015445 | doi=10.1001/archotol.134.11.1165 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19015445  }} </ref> a [[Morbidity & Mortality]] rate of 20% has been recorded in older patients treated for bronchogenic [[cyst]].<ref name="pmid21420068">{{cite journal| author=Makhija Z, Moir CR, Allen MS, Cassivi SD, Deschamps C, Nichols FC | display-authors=etal| title=Surgical management of congenital cystic lung malformations in older patients. | journal=Ann Thorac Surg | year= 2011 | volume= 91 | issue= 5 | pages= 1568-73; discussion 1573 | pmid=21420068 | doi=10.1016/j.athoracsur.2011.01.080 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21420068  }} </ref>
== Diagnostic Study of Choice ==
== Diagnostic Study of Choice ==
[[Excision]] and [[H&E stain|Hematoxylin and Eosin staining]]<ref name="pmid17874358">{{cite journal| author=Chuang KH, Huang TW, Cheng YL, Chen JC, Tzao C, Chang H | display-authors=etal| title=Esophageal bronchogenic cyst: a rare entity. | journal=Z Gastroenterol | year= 2007 | volume= 45 | issue= 9 | pages= 958-60 | pmid=17874358 | doi=10.1055/s-2007-963069 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17874358  }} </ref>
[[Excision]] and [[H&E stain|Hematoxylin and Eosin staining]].
===== Diagnostic results =====
===== Diagnostic results =====
Cillated [[columar epithelia]] cells is definitive for broncogenic [[cyst]].<ref name="pmid17874358">{{cite journal| author=Chuang KH, Huang TW, Cheng YL, Chen JC, Tzao C, Chang H | display-authors=etal| title=Esophageal bronchogenic cyst: a rare entity. | journal=Z Gastroenterol | year= 2007 | volume= 45 | issue= 9 | pages= 958-60 | pmid=17874358 | doi=10.1055/s-2007-963069 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17874358  }} </ref><ref name="pmid26986156">{{cite journal| author=Han C, Lin R, Yu J, Zhang Q, Zhang Y, Liu J | display-authors=etal| title=A Case Report of Esophageal Bronchogenic Cyst and Review of the Literature With an Emphasis on Endoscopic Ultrasonography Appearance. | journal=Medicine (Baltimore) | year= 2016 | volume= 95 | issue= 11 | pages= e3111 | pmid=26986156 | doi=10.1097/MD.0000000000003111 | pmc=4839937 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26986156  }} </ref><ref name="pmid31462259">{{cite journal| author=Yang X, Zong Y, Zhao HY, Wu YD, Ji M| title=Complete excision of esophageal bronchogenic cyst by endoscopic submucosal tunnel dissection: a case presentation. | journal=BMC Gastroenterol | year= 2019 | volume= 19 | issue= 1 | pages= 155 | pmid=31462259 | doi=10.1186/s12876-019-1072-3 | pmc=6714396 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31462259  }} </ref><ref name="pmid8902460">{{cite journal| author=Aktoğu S, Yuncu G, Halilçolar H, Ermete S, Buduneli T| title=Bronchogenic cysts: clinicopathological presentation and treatment. | journal=Eur Respir J | year= 1996 | volume= 9 | issue= 10 | pages= 2017-21 | pmid=8902460 | doi=10.1183/09031936.96.09102017 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8902460  }} </ref>
Cillated [[columar epithelia]] cells is definitive for broncogenic [[cyst]].
==== Diagnostic criteria ====
==== Diagnostic criteria ====
Cystic mass producing compressive symptoms.  
Cystic mass-producing compressive symptoms.
 
==History and symptoms==
==History and symptoms==
The majority of patients with bronchogenic [[cyst]]  are [[asymptomatic]] and are diagnosed during investigations for other pathologies.<ref name="pmid17859095">{{cite journal| author=Maier HC| title=Bronchiogenic Cysts of the Mediastinum. | journal=Ann Surg | year= 1948 | volume= 127 | issue= 3 | pages= 476-502 | pmid=17859095 | doi=10.1097/00000658-194803000-00010 | pmc=1513836 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17859095  }} </ref><ref name="pmid31462259">{{cite journal| author=Yang X, Zong Y, Zhao HY, Wu YD, Ji M| title=Complete excision of esophageal bronchogenic cyst by endoscopic submucosal tunnel dissection: a case presentation. | journal=BMC Gastroenterol | year= 2019 | volume= 19 | issue= 1 | pages= 155 | pmid=31462259 | doi=10.1186/s12876-019-1072-3 | pmc=6714396 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31462259  }} </ref><ref name="pmid480084">{{cite journal| author=Ramenofsky ML, Leape LL, McCauley RG| title=Bronchogenic cyst. | journal=J Pediatr Surg | year= 1979 | volume= 14 | issue= 3 | pages= 219-24 | pmid=480084 | doi=10.1016/s0022-3468(79)80474-1 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=480084  }} </ref>
The majority of patients with bronchogenic [[cyst]]  are [[asymptomatic]] and are diagnosed during investigations for other pathologies.


When symptomatic, clinical presentation of bronchogenic [[cyst]] depends on the age of the patient, size and the location of the [[cyst]].<ref name="pmid17859095">{{cite journal| author=Maier HC| title=Bronchiogenic Cysts of the Mediastinum. | journal=Ann Surg | year= 1948 | volume= 127 | issue= 3 | pages= 476-502 | pmid=17859095 | doi=10.1097/00000658-194803000-00010 | pmc=1513836 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17859095  }} </ref><ref name="pmid25746696">{{cite journal| author=Jiang JH, Yen SL, Lee SY, Chuang JH| title=Differences in the distribution and presentation of bronchogenic cysts between adults and children. | journal=J Pediatr Surg | year= 2015 | volume= 50 | issue= 3 | pages= 399-401 | pmid=25746696 | doi=10.1016/j.jpedsurg.2014.06.008 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25746696  }} </ref>
When symptomatic, the clinical presentation of bronchogenic [[cyst]] depends on the age of the patient, size and the location of the [[cyst]].


'''In infants bronchogenic cyst presents with''' <ref name="pmid19015445">{{cite journal| author=Teissier N, Elmaleh-Bergès M, Ferkdadji L, François M, Van den Abbeele T| title=Cervical bronchogenic cysts: usual and unusual clinical presentations. | journal=Arch Otolaryngol Head Neck Surg | year= 2008 | volume= 134 | issue= 11 | pages= 1165-9 | pmid=19015445 | doi=10.1001/archotol.134.11.1165 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19015445  }} </ref><ref name="pmid8651761">{{cite journal| author=Ribet ME, Copin MC, Gosselin BH| title=Bronchogenic cysts of the lung. | journal=Ann Thorac Surg | year= 1996 | volume= 61 | issue= 6 | pages= 1636-40 | pmid=8651761 | doi=10.1016/0003-4975(96)00172-5 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8651761  }} </ref><ref name="pmid27986331">{{cite journal| author=Hsu CG, Heller M, Johnston GS, Felberbaum M| title=An Unusual Cause of Airway Compromise in the Emergency Department: Mediastinal Bronchogenic Cyst. | journal=J Emerg Med | year= 2017 | volume= 52 | issue= 3 | pages= e91-e93 | pmid=27986331 | doi=10.1016/j.jemermed.2016.11.004 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27986331  }} </ref><ref name="pmid25746696">{{cite journal| author=Jiang JH, Yen SL, Lee SY, Chuang JH| title=Differences in the distribution and presentation of bronchogenic cysts between adults and children. | journal=J Pediatr Surg | year= 2015 | volume= 50 | issue= 3 | pages= 399-401 | pmid=25746696 | doi=10.1016/j.jpedsurg.2014.06.008 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25746696  }} </ref><ref name="pmid27822780">{{cite journal| author=Lin JS, Yu YR, Chiou EH, Chumpitazi BP, Schady DA, Brandt ML| title=Intramural esophageal bronchogenic cyst mimicking achalasia in a toddler. | journal=Pediatr Surg Int | year= 2017 | volume= 33 | issue= 1 | pages= 119-123 | pmid=27822780 | doi=10.1007/s00383-016-3994-y | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27822780  }} </ref><ref name="pmid26112048">{{cite journal| author=Thaller P, Blanchet C, Badr M, Mesnage R, Leboucq N, Mondain M | display-authors=etal| title=Neonatal respiratory distress syndrome revealing a cervical bronchogenic cyst: a case report. | journal=BMC Pediatr | year= 2015 | volume= 15 | issue=  | pages= 72 | pmid=26112048 | doi=10.1186/s12887-015-0363-2 | pmc=4491209 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26112048  }} </ref><ref name="pmid29099998">{{cite journal| author=Brugha R, Semple T, Cook J, Dusmet M, Rosenthal M| title=Two Bronchogenic Cysts Causing Tracheal Stenosis in an Infant. | journal=Am J Respir Crit Care Med | year= 2018 | volume= 197 | issue= 2 | pages= 261-262 | pmid=29099998 | doi=10.1164/rccm.201708-1611IM | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29099998  }} </ref>
'''In infants bronchogenic cyst presents with'''  
*[[respiratory distress]]  
*[[respiratory distress]]  
*Increasing [[stridor]]
*Increasing [[stridor]]
Line 89: Line 94:


'''In children and adults, bronchogenic cyst presents with'''  
'''In children and adults, bronchogenic cyst presents with'''  
*Dull [[chest pain]],<ref name="pmid17859095">{{cite journal| author=Maier HC| title=Bronchiogenic Cysts of the Mediastinum. | journal=Ann Surg | year= 1948 | volume= 127 | issue= 3 | pages= 476-502 | pmid=17859095 | doi=10.1097/00000658-194803000-00010 | pmc=1513836 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17859095  }} </ref><ref name="pmid12809250">{{cite journal| author=Sarper A, Ayten A, Golbasi I, Demircan A, Isin E| title=Bronchogenic cyst. | journal=Tex Heart Inst J | year= 2003 | volume= 30 | issue= 2 | pages= 105-8 | pmid=12809250 | doi= | pmc=161894 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12809250  }} </ref><ref name="pmid27068723">{{cite journal| author=Chumakova M, Morris-Stiff G, Khachaturov V, Ibrahim S| title=Bronchogenic cyst arising from the crus of the left hemidiaphragm. | journal=BMJ Case Rep | year= 2016 | volume= 2016 | issue=  | pages=  | pmid=27068723 | doi=10.1136/bcr-2015-213658 | pmc=4840741 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27068723  }} </ref><ref name="pmid26986156">{{cite journal| author=Han C, Lin R, Yu J, Zhang Q, Zhang Y, Liu J | display-authors=etal| title=A Case Report of Esophageal Bronchogenic Cyst and Review of the Literature With an Emphasis on Endoscopic Ultrasonography Appearance. | journal=Medicine (Baltimore) | year= 2016 | volume= 95 | issue= 11 | pages= e3111 | pmid=26986156 | doi=10.1097/MD.0000000000003111 | pmc=4839937 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26986156  }} </ref> with radiation to the shoulder in diaphragmatic broncogenic [[cyst]].<ref name="pmid25131363">{{cite journal| author=Legras A, Mordant P, Gibault L, Hernigou A, Le Pimpec Barthes F, Riquet M| title=[Diaphragmatic bronchogenic cyst: an exceptional location]. | journal=Rev Pneumol Clin | year= 2014 | volume= 70 | issue= 6 | pages= 357-61 | pmid=25131363 | doi=10.1016/j.pneumo.2014.05.002 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25131363  }} </ref><ref name="pmid27986331">{{cite journal| author=Hsu CG, Heller M, Johnston GS, Felberbaum M| title=An Unusual Cause of Airway Compromise in the Emergency Department: Mediastinal Bronchogenic Cyst. | journal=J Emerg Med | year= 2017 | volume= 52 | issue= 3 | pages= e91-e93 | pmid=27986331 | doi=10.1016/j.jemermed.2016.11.004 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27986331  }} </ref>
*Dull [[chest pain]] with radiation to the shoulder in diaphragmatic broncogenic [[cyst]].
*[[Cough]]<ref name="pmid26986156">{{cite journal| author=Han C, Lin R, Yu J, Zhang Q, Zhang Y, Liu J | display-authors=etal| title=A Case Report of Esophageal Bronchogenic Cyst and Review of the Literature With an Emphasis on Endoscopic Ultrasonography Appearance. | journal=Medicine (Baltimore) | year= 2016 | volume= 95 | issue= 11 | pages= e3111 | pmid=26986156 | doi=10.1097/MD.0000000000003111 | pmc=4839937 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26986156  }} </ref> <ref name="pmid12809250">{{cite journal| author=Sarper A, Ayten A, Golbasi I, Demircan A, Isin E| title=Bronchogenic cyst. | journal=Tex Heart Inst J | year= 2003 | volume= 30 | issue= 2 | pages= 105-8 | pmid=12809250 | doi= | pmc=161894 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12809250  }} </ref><ref name="pmid30846076">{{cite journal| author=Ayub II, Balakrishnan H, Arshad AM, Manimaran N, Thangaswamy D, Chockalingam C| title=A 44-Year-Old Man With Nonproductive Cough and Sensation of Heaviness Over the Upper Chest. | journal=Chest | year= 2019 | volume= 155 | issue= 3 | pages= e65-e68 | pmid=30846076 | doi=10.1016/j.chest.2018.09.035 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30846076  }} </ref>
*[[Cough]]
*Progressive [[dysphagia]]<ref name="pmid17859095">{{cite journal| author=Maier HC| title=Bronchiogenic Cysts of the Mediastinum. | journal=Ann Surg | year= 1948 | volume= 127 | issue= 3 | pages= 476-502 | pmid=17859095 | doi=10.1097/00000658-194803000-00010 | pmc=1513836 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17859095  }} </ref><ref name="pmid26986156">{{cite journal| author=Han C, Lin R, Yu J, Zhang Q, Zhang Y, Liu J | display-authors=etal| title=A Case Report of Esophageal Bronchogenic Cyst and Review of the Literature With an Emphasis on Endoscopic Ultrasonography Appearance. | journal=Medicine (Baltimore) | year= 2016 | volume= 95 | issue= 11 | pages= e3111 | pmid=26986156 | doi=10.1097/MD.0000000000003111 | pmc=4839937 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26986156  }} </ref>
*Progressive [[dysphagia]]
*[[Odynophagia]]<ref name="pmid26986156">{{cite journal| author=Han C, Lin R, Yu J, Zhang Q, Zhang Y, Liu J | display-authors=etal| title=A Case Report of Esophageal Bronchogenic Cyst and Review of the Literature With an Emphasis on Endoscopic Ultrasonography Appearance. | journal=Medicine (Baltimore) | year= 2016 | volume= 95 | issue= 11 | pages= e3111 | pmid=26986156 | doi=10.1097/MD.0000000000003111 | pmc=4839937 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26986156  }} </ref>
*[[Odynophagia]]
*[[Wheeze|wheezing]]<ref name="pmid17859095">{{cite journal| author=Maier HC| title=Bronchiogenic Cysts of the Mediastinum. | journal=Ann Surg | year= 1948 | volume= 127 | issue= 3 | pages= 476-502 | pmid=17859095 | doi=10.1097/00000658-194803000-00010 | pmc=1513836 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17859095  }} </ref> 
*[[Wheeze|wheezing]]
*Adobminal [[bloating]]<ref name="pmid26823885">{{cite journal| author=Gou Y, Wang Y, Fang H, Xu X, Yu W, Zhang K | display-authors=etal| title=Bronchogenic cyst in the hepatogastric ligament masquerading as an esophageal mesenchymal tumor: a case report. | journal=Int J Clin Exp Pathol | year= 2015 | volume= 8 | issue= 11 | pages= 15307-11 | pmid=26823885 | doi= | pmc=4713671 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26823885  }} </ref>
*Adobminal [[bloating]]
*[[Fever]]<ref name="pmid12809250">{{cite journal| author=Sarper A, Ayten A, Golbasi I, Demircan A, Isin E| title=Bronchogenic cyst. | journal=Tex Heart Inst J | year= 2003 | volume= 30 | issue= 2 | pages= 105-8 | pmid=12809250 | doi= | pmc=161894 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12809250  }} </ref>
*[[Fever]]
*Palpable [[neck massess|neck mass]]<ref name="pmid25746696">{{cite journal| author=Jiang JH, Yen SL, Lee SY, Chuang JH| title=Differences in the distribution and presentation of bronchogenic cysts between adults and children. | journal=J Pediatr Surg | year= 2015 | volume= 50 | issue= 3 | pages= 399-401 | pmid=25746696 | doi=10.1016/j.jpedsurg.2014.06.008 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25746696  }} </ref>
*Palpable [[neck massess|neck mass]]
*[[Empyema|purulent sputum]]<ref name="pmid17859095">{{cite journal| author=Maier HC| title=Bronchiogenic Cysts of the Mediastinum. | journal=Ann Surg | year= 1948 | volume= 127 | issue= 3 | pages= 476-502 | pmid=17859095 | doi=10.1097/00000658-194803000-00010 | pmc=1513836 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17859095  }} </ref>
*[[Empyema|purulent sputum]]
*[[Hemoptysis]]<ref name="pmid12809250">{{cite journal| author=Sarper A, Ayten A, Golbasi I, Demircan A, Isin E| title=Bronchogenic cyst. | journal=Tex Heart Inst J | year= 2003 | volume= 30 | issue= 2 | pages= 105-8 | pmid=12809250 | doi= | pmc=161894 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12809250  }} </ref>
*[[Hemoptysis]]
*[[Dyspnea]]<ref name="pmid17874358">{{cite journal| author=Chuang KH, Huang TW, Cheng YL, Chen JC, Tzao C, Chang H | display-authors=etal| title=Esophageal bronchogenic cyst: a rare entity. | journal=Z Gastroenterol | year= 2007 | volume= 45 | issue= 9 | pages= 958-60 | pmid=17874358 | doi=10.1055/s-2007-963069 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17874358  }} </ref><ref name="pmid27986331">{{cite journal| author=Hsu CG, Heller M, Johnston GS, Felberbaum M| title=An Unusual Cause of Airway Compromise in the Emergency Department: Mediastinal Bronchogenic Cyst. | journal=J Emerg Med | year= 2017 | volume= 52 | issue= 3 | pages= e91-e93 | pmid=27986331 | doi=10.1016/j.jemermed.2016.11.004 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27986331  }} </ref>
*[[Dyspnea]]
*[[Anorexia]] and/or [[weight loss]]<ref name="pmid8902460">{{cite journal| author=Aktoğu S, Yuncu G, Halilçolar H, Ermete S, Buduneli T| title=Bronchogenic cysts: clinicopathological presentation and treatment. | journal=Eur Respir J | year= 1996 | volume= 9 | issue= 10 | pages= 2017-21 | pmid=8902460 | doi=10.1183/09031936.96.09102017 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8902460  }} </ref>
*[[Anorexia]] and/or [[weight loss]]
*[[Dizziness]]<ref name="pmid25780019">{{cite journal| author=Xu Q, Feng Y, Ye K, Zhou Y, Zhan R| title=Bronchogenic cyst in left anterior cranial fossa. | journal=Neurology | year= 2015 | volume= 84 | issue= 11 | pages= 1181-2 | pmid=25780019 | doi=10.1212/WNL.0000000000001368 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25780019  }} </ref>
*[[Dizziness]]
*[[Paroxysmal supraventricular tachycardia]]<ref name="pmid26329634">{{cite journal| author=Mega S| title=[Anterior Mediastinal Bronchogenic Cyst Associated with paroxysmal supraventricular tachycardia ; Report of a Case]. | journal=Kyobu Geka | year= 2015 | volume= 68 | issue= 10 | pages= 871-3 | pmid=26329634 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26329634  }} </ref>
*[[Paroxysmal supraventricular tachycardia]]
*[[Atrioventricular block]]<ref name="pmid28139004">{{cite journal| author=Miwa E, Tani T, Okada Y, Furukawa Y| title=A rare cardiac tumor: Bronchogenic cyst of interatrial septum. | journal=Echocardiography | year= 2017 | volume= 34 | issue= 3 | pages= 474-475 | pmid=28139004 | doi=10.1111/echo.13445 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28139004  }} </ref>
*[[Atrioventricular block]]
*[[Premature atrial contraction|Atrial]] and [[Premature ventricular contraction|ventricular premature complexes]]<ref name="pmid29897508">{{cite journal| author=Blesneac C, Horvath E, Muntean I, Benedek T, Toganel R| title=Intracardiac bronchogenic cyst associated with ventricular septal defect: an extremely rare feature in children. | journal=Eur Heart J Cardiovasc Imaging | year= 2018 | volume= 19 | issue= 9 | pages= 1074 | pmid=29897508 | doi=10.1093/ehjci/jey078 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29897508  }} </ref>
*[[Premature atrial contraction|Atrial]] and [[Premature ventricular contraction|ventricular premature complexes]]
*[[Amnesia|Memory impairment]]<ref name="pmid31348319">{{cite journal| author=Bian B, Yu M, Liu S, Li S, Wei Y, Zhang B| title=A suprasellar bronchogenic cyst: A case report. | journal=Medicine (Baltimore) | year= 2019 | volume= 98 | issue= 30 | pages= e16650 | pmid=31348319 | doi=10.1097/MD.0000000000016650 | pmc=6709100 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31348319  }} </ref>
*[[Amnesia|Memory impairment]]
*[[Asthenia]]<ref name="pmid31348319">{{cite journal| author=Bian B, Yu M, Liu S, Li S, Wei Y, Zhang B| title=A suprasellar bronchogenic cyst: A case report. | journal=Medicine (Baltimore) | year= 2019 | volume= 98 | issue= 30 | pages= e16650 | pmid=31348319 | doi=10.1097/MD.0000000000016650 | pmc=6709100 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31348319  }} </ref><ref name="pmid26097578">{{cite journal| author=Zou MX, Hu JR, Kang YJ, Li J, Lv GH, She XL| title=Bronchogenic cyst of the conus medullaris with spinal cord tethering: a case report and review of the literature. | journal=Int J Clin Exp Pathol | year= 2015 | volume= 8 | issue= 4 | pages= 3937-42 | pmid=26097578 | doi= | pmc=4466965 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26097578  }} </ref><ref name="pmid29390371">{{cite journal| author=Lee HD, Han SH, Park SB, Ko Y, Lee KH| title=An intradural extramedullary bronchogenic cyst in the thoracolumbar spine: A case report. | journal=Medicine (Baltimore) | year= 2017 | volume= 96 | issue= 50 | pages= e9263 | pmid=29390371 | doi=10.1097/MD.0000000000009263 | pmc=5815783 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29390371  }} </ref>
*[[Asthenia]]
*[[limp|Limping]]<ref name="pmid29390371">{{cite journal| author=Lee HD, Han SH, Park SB, Ko Y, Lee KH| title=An intradural extramedullary bronchogenic cyst in the thoracolumbar spine: A case report. | journal=Medicine (Baltimore) | year= 2017 | volume= 96 | issue= 50 | pages= e9263 | pmid=29390371 | doi=10.1097/MD.0000000000009263 | pmc=5815783 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29390371  }} </ref>
*[[limp|Limping]]
*[[Seizure]] and [[loss of consciousness]]<ref name="pmid26969135">{{cite journal| author=Khawar M, Elmahrouk A, Chaikhouni A| title=Air embolism during air flight in a passenger with bronchogenic cyst. | journal=J Thorac Cardiovasc Surg | year= 2016 | volume= 152 | issue= 1 | pages= e1-2 | pmid=26969135 | doi=10.1016/j.jtcvs.2016.02.014 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26969135  }} </ref>
*[[Seizure]] and [[loss of consciousness]]
*[[Sciatica]]<ref name="pmid28762109">{{cite journal| author=Candy N, Young A, Devadass A, Dean A, McMillen J, Trivedi R| title=Dual lumbar bronchogenic and arachnoid cyst presenting with sciatica and left foot drop. | journal=Acta Neurochir (Wien) | year= 2017 | volume= 159 | issue= 10 | pages= 2029-2032 | pmid=28762109 | doi=10.1007/s00701-017-3284-z | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28762109  }} </ref>
*[[Sciatica]]
*[[Back pain]]<ref name="pmid26097578">{{cite journal| author=Zou MX, Hu JR, Kang YJ, Li J, Lv GH, She XL| title=Bronchogenic cyst of the conus medullaris with spinal cord tethering: a case report and review of the literature. | journal=Int J Clin Exp Pathol | year= 2015 | volume= 8 | issue= 4 | pages= 3937-42 | pmid=26097578 | doi= | pmc=4466965 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26097578  }} </ref><ref name="pmid27222776">{{cite journal| author=Atoini F, Ouarssani A, Ouadnouni Y, Smahi M| title=Unusual mode of presentation of intrathoracic bronchogenic cyst: A double location. | journal=Respir Med Case Rep | year= 2016 | volume= 17 | issue=  | pages= 12-6 | pmid=27222776 | doi=10.1016/j.rmcr.2015.10.001 | pmc=4821250 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27222776  }} </ref>
*[[Back pain]]
*[[Neuralgia]]<ref name="pmid27222776">{{cite journal| author=Atoini F, Ouarssani A, Ouadnouni Y, Smahi M| title=Unusual mode of presentation of intrathoracic bronchogenic cyst: A double location. | journal=Respir Med Case Rep | year= 2016 | volume= 17 | issue=  | pages= 12-6 | pmid=27222776 | doi=10.1016/j.rmcr.2015.10.001 | pmc=4821250 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27222776  }} </ref>
*[[Neuralgia]]
*[[Urinary incontinence]]<ref name="pmid26097578">{{cite journal| author=Zou MX, Hu JR, Kang YJ, Li J, Lv GH, She XL| title=Bronchogenic cyst of the conus medullaris with spinal cord tethering: a case report and review of the literature. | journal=Int J Clin Exp Pathol | year= 2015 | volume= 8 | issue= 4 | pages= 3937-42 | pmid=26097578 | doi= | pmc=4466965 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26097578  }} </ref>
*[[Urinary incontinence]]
 
==Physical examinaton==
 
Physical examination of patients with bronchogenic [[cyst]] is usually normal. On rare occasions, the following signs can be seen
*[[Cough]]
*[[Wheeze|wheezing]]
*[[Stridor]]
*[[Hemoptysis]]
*[[Dyspnea]]
*[[Tracheal deviation]]
*[[ascites|Fluid-thrill]]
*[[Anorexia]] and/or [[weight loss]]
*[[Fever]]
*[[Asthenia]]
*[[Foot drop]]
*[[Atrophy]]
*[[Heart murmur]]
*[[Tenderness]]
*Cutanous pigmentation
*Negative [[Neurological examination|knee]] and [[Neurological examination|ankle reflexes]]
*[[Hypoesthesia|Numbness]]
 
==Laboratory findings==
An elevated serum [[tumor marker|tumor makers]] CA125 and CA19-9, which is usually suggestive of progression/complication.
 
==CT==
CT scan may be helpful in the diagnosis of bronchogenic [[cyst]]. The density of bronchogenic [[cysts]] is variable from water density to high density due to blood, anthracotic pigment, increased calcium content, or increased protein content of the fluid. Findings on CT scan suggestive of bronchogenic [[cyst]] is an
*[[cyst|Cysic mass]] with air-fluid levels.
*ovoid and well-defined encapsulated low-density [[cyst|cystic mass]] with no contrast enhancement.
*Thin subtle walls.
 
==MRI==
MRI may be helpful in the diagnosis of bronchogenic [[cyst]]. After contrast injection, enhancement of the [[cyst]] is frequently absent. Findings on MRI suggestive of bronchogenic [[cyst]] include
*T1-weighted images show ipointense signal
*T2-weighted images show hyperintense signal.
 
==Ultrasound==
[[ultrasound]] may be helpful in the diagnosis of bronchogenic [[cyst]]. Finding on an [[ultrasound]] suggestive of bronchogenic [[cyst]] include
*On endobronchial [[ultrasound]], an anechoic or hypoechoic fluid-filled solid mass.
*On transthoracic echocardiography revealing intracardiac [[cyst|cystic mass]].
*On [[Endoscopy|endoscopic ultrasonography]], which demonstartes abdominal anatomic relations of the [[cyst]].
 
==Other Diagnostic Studies==
Other diagnostic studies for bronchogenic cyst include:
[[Excision]] and [[H&E stain|Hematoxylin and Eosin staining]], which demonstrates ciliated [[columar epithelia]] cells is definitive for bronchogenic [[cyst]]
*[[Immunohistochemistry|Immunohistochemical staining]] of bronchogenic [[cyst]] of the esophagus , which demonstrates a positive expression of CA199 and CA125.
*[[Bronchoscopy]], which demonstrates pink [[cyst|cystic mass]] with bronchial attachment
*[[endoscopy|Gastroendoscopy]] which demonstartes abdominal anatomic relations of the [[cyst]].
*[[fluorodeoxyglucose]]-[[positron emission tomography]] to confirm [[cyst]] infection.
 
==Treatment==
===Medical therapy===
The mainstay of treatment for bronchogenic [[cyst]] is [[Bronchogenic cyst surgery|surgery]].
===Surgery===
Surgery is the mainstay of treatment for bronchogenic [[cyst]] even when the patients are asymptomatic, a conservative approach is not approved.
 
==Primary prevention==
There are no established measures for the primary prevention of bronchogenic [[cyst]].
==Secondaryy prevention==
There are no established measures for the secondary prevention of bronchogenic [[cyst]].
 
 


==References==
==References==

Latest revision as of 01:14, 22 September 2020

Bronchogenic cyst Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Bronchogenic cyst from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Interventions

Surgery

Primary Prevention

Secondary Prevention

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Joanna Ekabua, M.D. [2]

Overview

Bronchogenic cyst is a rare benign congenital malformation of the tracheobronchial tree derived from the ventral aspect of the foregut. It most frequently occurs in the middle mediastinum, in the early stages of gestation or in the lungs, at the later stages of gestation. Atypical locations may be explained by its embryologic origin. Patients with bronchogenic cyst may be asymptomatic or present with respiratory distress, increasing stridor, feeding difficulties, chest pain, cough, progressive dysphagia, odynophagia, purulent sputum, dyspnea, anorexia and/orweight loss. Radiologic findings are useful to differentiate bronchogenic cysts from other cysts but they may not always confirm the diagnosis. Diagnosis is confirmed by surgical excision, which is curative, and histological findings of ciliated columnar epithelial lining of the cyst.

Historical Perspective

There is limited information about the historical perspective of bronchogenic cyst.

Classification

Bronchogenic cyst can be classified based on location; pulmonary and extrapulmonary.

Pathophysiology

It is thought that bronchogenic cyst is the result of abnormal budding of the ventral portion of the primitive foregut between days 26 - 40 of gestation.

Causes

The cause of bronchogenic cysts is undetermined.

Differentiating Bronchogenic cyst from other Diseases

Differentiating bronchogenic cyst from lung abcess, thymic cyst, and esophageal duplication cysts.

Bronchogenic cyst epidemiology and demographics|Epidemiology and Demographics

There is no racial predilection to bronchogenic cyst. Bronchogenic cyst is slightly more prevalent in men and often remain undetected until the third or fourth decade of life.

Risk factors

There are no established risk factors for bronchogenic cyst.

Screening

There is insufficient evidence to recommend routine screening for bronchogenic cyst as it is usually an incidental finding.

Natural history, complications and prognosis

Natural History

The symptoms of bronchogenic cyst usually develop in the third to fourth decade of life and start with symptoms such as

Complication

Common complications of bronchogenic cyst include

Prognosis

Prognosis is generally good, a Morbidity & Mortality rate of 20% has been recorded in older patients treated for bronchogenic cyst.

Diagnostic Study of Choice

Excision and Hematoxylin and Eosin staining.

Diagnostic results

Cillated columar epithelia cells is definitive for broncogenic cyst.

Diagnostic criteria

Cystic mass-producing compressive symptoms.

History and symptoms

The majority of patients with bronchogenic cyst are asymptomatic and are diagnosed during investigations for other pathologies.

When symptomatic, the clinical presentation of bronchogenic cyst depends on the age of the patient, size and the location of the cyst.

In infants bronchogenic cyst presents with

In children and adults, bronchogenic cyst presents with

Physical examinaton

Physical examination of patients with bronchogenic cyst is usually normal. On rare occasions, the following signs can be seen

Laboratory findings

An elevated serum tumor makers CA125 and CA19-9, which is usually suggestive of progression/complication.

CT

CT scan may be helpful in the diagnosis of bronchogenic cyst. The density of bronchogenic cysts is variable from water density to high density due to blood, anthracotic pigment, increased calcium content, or increased protein content of the fluid. Findings on CT scan suggestive of bronchogenic cyst is an

  • Cysic mass with air-fluid levels.
  • ovoid and well-defined encapsulated low-density cystic mass with no contrast enhancement.
  • Thin subtle walls.

MRI

MRI may be helpful in the diagnosis of bronchogenic cyst. After contrast injection, enhancement of the cyst is frequently absent. Findings on MRI suggestive of bronchogenic cyst include

  • T1-weighted images show ipointense signal
  • T2-weighted images show hyperintense signal.

Ultrasound

ultrasound may be helpful in the diagnosis of bronchogenic cyst. Finding on an ultrasound suggestive of bronchogenic cyst include

Other Diagnostic Studies

Other diagnostic studies for bronchogenic cyst include: Excision and Hematoxylin and Eosin staining, which demonstrates ciliated columar epithelia cells is definitive for bronchogenic cyst

Treatment

Medical therapy

The mainstay of treatment for bronchogenic cyst is surgery.

Surgery

Surgery is the mainstay of treatment for bronchogenic cyst even when the patients are asymptomatic, a conservative approach is not approved.

Primary prevention

There are no established measures for the primary prevention of bronchogenic cyst.

Secondaryy prevention

There are no established measures for the secondary prevention of bronchogenic cyst.


References

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