Mirizzi's syndrome natural history, complications and prognosis: Difference between revisions

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'''Natural History'''
'''Natural History'''
* Diagnosis of Mirizzi's syndrome is often missed due to its rarity.
* Mirizzi syndrome frequently presents in an [[acute]] form. However, [[chronic]] form is equally common or an even more common form of presentation.
* It presents with symptoms of recurrent [[cholangitis]], [[jaundice]] and [[right upper quadrant]] pain.
* Clinical presentation of Mirizzi's syndrome could be non-specific.
* Acutely, it presents with symptoms like that of [[Acute cholecystitis]].
* However, it presents most commonly with [[obstructive jaundice]] (60%-100%), accompanied by [[right upper quadrant]] abdominal pain (50%-100%) and fever. <ref name="pmid23002333">{{cite journal |vauthors=Beltrán MA |title=Mirizzi syndrome: history, current knowledge and proposal of a simplified classification |journal=World J. Gastroenterol. |volume=18 |issue=34 |pages=4639–50 |date=September 2012 |pmid=23002333 |pmc=3442202 |doi=10.3748/wjg.v18.i34.4639 |url=}}</ref>
* Surgery management is the mainstay treatment. <ref name="pmid29369192">{{cite journal |vauthors=Chen H, Siwo EA, Khu M, Tian Y |title=Current trends in the management of Mirizzi Syndrome: A review of literature |journal=Medicine (Baltimore) |volume=97 |issue=4 |pages=e9691 |date=January 2018 |pmid=29369192 |pmc=5794376 |doi=10.1097/MD.0000000000009691 |url=}}</ref>
* Patient may be a known or suspected case of [[gallstone]] disease.
* Previous history of jaundice is sometimes present.
* Patients frequently present in the setting of [[acute cholecystitis]], [[acute cholangitis]], [[acute pancreatitis]] or [[gallstone ileus]].
 
'''Complications'''
* Cholecystocholedochal [[fistula]]
* [[Cholecystoenteric]] fistula
* Cutaneous fistulas.
* [[Secondary biliary cirrhosis]].
* Delayed onset [[biliary strictures]].
* Operative and postoperative morbidity and mortality (according to the severity of lesion).
 
'''Prognosis'''
* Severe inflammation and delayed or missed diagnosis may result in high [[morbidity]] and mortality. Surgical management is the mainstay treatment. <ref name="pmid29369192">{{cite journal |vauthors=Chen H, Siwo EA, Khu M, Tian Y |title=Current trends in the management of Mirizzi Syndrome: A review of literature |journal=Medicine (Baltimore) |volume=97 |issue=4 |pages=e9691 |date=January 2018 |pmid=29369192 |pmc=5794376 |doi=10.1097/MD.0000000000009691 |url=}}</ref>


==References==
==References==

Latest revision as of 05:52, 29 July 2020

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Natural History, Complications and Prognosis

Natural History

Complications

Prognosis

  • Severe inflammation and delayed or missed diagnosis may result in high morbidity and mortality. Surgical management is the mainstay treatment. [2]

References

  1. Beltrán MA (September 2012). "Mirizzi syndrome: history, current knowledge and proposal of a simplified classification". World J. Gastroenterol. 18 (34): 4639–50. doi:10.3748/wjg.v18.i34.4639. PMC 3442202. PMID 23002333.
  2. Chen H, Siwo EA, Khu M, Tian Y (January 2018). "Current trends in the management of Mirizzi Syndrome: A review of literature". Medicine (Baltimore). 97 (4): e9691. doi:10.1097/MD.0000000000009691. PMC 5794376. PMID 29369192.