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{{Renal agenesis}} | {{Renal agenesis}} | ||
{{CMG}} | {{CMG}} {{AE}} {{SHA}} | ||
== Overview == | == Overview == | ||
Renal agenesis may be classified as unilateral renal agenesis (URA) or bilateral renal agenesis (BRA). URA is the congenital absence of one [[kidney]] and BRA is the congenital absence of both [[Kidney|kidneys]] which is incompatible with life. Renal agenesis may be isolated or associated with other [[Anomaly|anomalies]] and [[Syndrome|syndromes]]. | |||
== Classification == | == Classification == | ||
Renal agenesis may be unilateral or bilateral:<ref name="pmid24524801">{{cite journal| author=Dias T, Sairam S, Kumarasiri S| title=Ultrasound diagnosis of fetal renal abnormalities. | journal=Best Pract Res Clin Obstet Gynaecol | year= 2014 | volume= 28 | issue= 3 | pages= 403-15 | pmid=24524801 | doi=10.1016/j.bpobgyn.2014.01.009 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24524801 }} </ref> | Renal agenesis may be unilateral or bilateral:<ref name="pmid24524801">{{cite journal| author=Dias T, Sairam S, Kumarasiri S| title=Ultrasound diagnosis of fetal renal abnormalities. | journal=Best Pract Res Clin Obstet Gynaecol | year= 2014 | volume= 28 | issue= 3 | pages= 403-15 | pmid=24524801 | doi=10.1016/j.bpobgyn.2014.01.009 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24524801 }} </ref> | ||
* Unilateral renal agenesis(URA) | * Unilateral renal agenesis (URA) | ||
** Congenital absence of one | ** Congenital absence of one [[kidney]]<ref name="pmid8540439">{{cite journal| author=Robson WL, Leung AK, Rogers RC| title=Unilateral renal agenesis. | journal=Adv Pediatr | year= 1995 | volume= 42 | issue= | pages= 575-92 | pmid=8540439 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8540439 }} </ref><ref name="pmid16956352">{{cite journal| author=Woolf AS, Hillman KA| title=Unilateral renal agenesis and the congenital solitary functioning kidney: developmental, genetic and clinical perspectives. | journal=BJU Int | year= 2007 | volume= 99 | issue= 1 | pages= 17-21 | pmid=16956352 | doi=10.1111/j.1464-410X.2006.06504.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16956352 }} </ref> | ||
** | ** The contra-lateral solitary [[kidney]] usually functions normally and may become hypertrophied<ref name="pmid19852048">{{cite journal| author=Cho JY, Moon MH, Lee YH, Kim KW, Kim SH| title=Measurement of compensatory hyperplasia of the contralateral kidney: usefulness for differential diagnosis of fetal unilateral empty renal fossa. | journal=Ultrasound Obstet Gynecol | year= 2009 | volume= 34 | issue= 5 | pages= 515-20 | pmid=19852048 | doi=10.1002/uog.7336 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19852048 }} </ref> | ||
* Bilateral renal agenesis (BRA) | * Bilateral renal agenesis (BRA) | ||
** Congenital absence of both kidneys<ref name="pmid31098643">{{cite journal| author=Huber C, Shazly SA, Blumenfeld YJ, Jelin E, Ruano R| title=Update on the Prenatal Diagnosis and Outcomes of Fetal Bilateral Renal Agenesis. | journal=Obstet Gynecol Surv | year= 2019 | volume= 74 | issue= 5 | pages= 298-302 | pmid=31098643 | doi=10.1097/OGX.0000000000000670 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31098643 }} </ref> | ** Congenital absence of both [[Kidney|kidneys]]<ref name="pmid31098643">{{cite journal| author=Huber C, Shazly SA, Blumenfeld YJ, Jelin E, Ruano R| title=Update on the Prenatal Diagnosis and Outcomes of Fetal Bilateral Renal Agenesis. | journal=Obstet Gynecol Surv | year= 2019 | volume= 74 | issue= 5 | pages= 298-302 | pmid=31098643 | doi=10.1097/OGX.0000000000000670 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31098643 }} </ref> | ||
** Incompatible with life<ref name="pmid24524801">{{cite journal| author=Dias T, Sairam S, Kumarasiri S| title=Ultrasound diagnosis of fetal renal abnormalities. | journal=Best Pract Res Clin Obstet Gynaecol | year= 2014 | volume= 28 | issue= 3 | pages= 403-15 | pmid=24524801 | doi=10.1016/j.bpobgyn.2014.01.009 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24524801 }} </ref> | ** Incompatible with life<ref name="pmid24524801">{{cite journal| author=Dias T, Sairam S, Kumarasiri S| title=Ultrasound diagnosis of fetal renal abnormalities. | journal=Best Pract Res Clin Obstet Gynaecol | year= 2014 | volume= 28 | issue= 3 | pages= 403-15 | pmid=24524801 | doi=10.1016/j.bpobgyn.2014.01.009 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24524801 }} </ref> | ||
Renal agenesis may be isolated or associated with other [[Anomaly|anomalies]] and [[Syndrome|syndromes]].<ref name="pmid28722320">{{cite journal| author=Laurichesse Delmas H, Kohler M, Doray B, Lémery D, Francannet C, Quistrebert J | display-authors=etal| title=Congenital unilateral renal agenesis: Prevalence, prenatal diagnosis, associated anomalies. Data from two birth-defect registries. | journal=Birth Defects Res | year= 2017 | volume= 109 | issue= 15 | pages= 1204-1211 | pmid=28722320 | doi=10.1002/bdr2.1065 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28722320 }} </ref><ref name="pmid23449343">{{cite journal| author=Westland R, Schreuder MF, Ket JC, van Wijk JA| title=Unilateral renal agenesis: a systematic review on associated anomalies and renal injury. | journal=Nephrol Dial Transplant | year= 2013 | volume= 28 | issue= 7 | pages= 1844-55 | pmid=23449343 | doi=10.1093/ndt/gft012 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23449343 }} </ref> | |||
==References== | ==References== | ||
Latest revision as of 13:17, 2 August 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shakiba Hassanzadeh, MD[2]
Overview
Renal agenesis may be classified as unilateral renal agenesis (URA) or bilateral renal agenesis (BRA). URA is the congenital absence of one kidney and BRA is the congenital absence of both kidneys which is incompatible with life. Renal agenesis may be isolated or associated with other anomalies and syndromes.
Classification
Renal agenesis may be unilateral or bilateral:[1]
- Unilateral renal agenesis (URA)
- Bilateral renal agenesis (BRA)
Renal agenesis may be isolated or associated with other anomalies and syndromes.[6][7]
References
- ↑ 1.0 1.1 Dias T, Sairam S, Kumarasiri S (2014). "Ultrasound diagnosis of fetal renal abnormalities". Best Pract Res Clin Obstet Gynaecol. 28 (3): 403–15. doi:10.1016/j.bpobgyn.2014.01.009. PMID 24524801.
- ↑ Robson WL, Leung AK, Rogers RC (1995). "Unilateral renal agenesis". Adv Pediatr. 42: 575–92. PMID 8540439.
- ↑ Woolf AS, Hillman KA (2007). "Unilateral renal agenesis and the congenital solitary functioning kidney: developmental, genetic and clinical perspectives". BJU Int. 99 (1): 17–21. doi:10.1111/j.1464-410X.2006.06504.x. PMID 16956352.
- ↑ Cho JY, Moon MH, Lee YH, Kim KW, Kim SH (2009). "Measurement of compensatory hyperplasia of the contralateral kidney: usefulness for differential diagnosis of fetal unilateral empty renal fossa". Ultrasound Obstet Gynecol. 34 (5): 515–20. doi:10.1002/uog.7336. PMID 19852048.
- ↑ Huber C, Shazly SA, Blumenfeld YJ, Jelin E, Ruano R (2019). "Update on the Prenatal Diagnosis and Outcomes of Fetal Bilateral Renal Agenesis". Obstet Gynecol Surv. 74 (5): 298–302. doi:10.1097/OGX.0000000000000670. PMID 31098643.
- ↑ Laurichesse Delmas H, Kohler M, Doray B, Lémery D, Francannet C, Quistrebert J; et al. (2017). "Congenital unilateral renal agenesis: Prevalence, prenatal diagnosis, associated anomalies. Data from two birth-defect registries". Birth Defects Res. 109 (15): 1204–1211. doi:10.1002/bdr2.1065. PMID 28722320.
- ↑ Westland R, Schreuder MF, Ket JC, van Wijk JA (2013). "Unilateral renal agenesis: a systematic review on associated anomalies and renal injury". Nephrol Dial Transplant. 28 (7): 1844–55. doi:10.1093/ndt/gft012. PMID 23449343.