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| {| class="wikitable sortable"
| | [[Syncope]] is classified into three types: |
| ! Drug Class
| | * [[Cardiac]] |
| ! Drug
| | * [[Neurogenic]] |
| ! Initial daily dose, target dose (mg)
| | * [[Vasovagal syncope|vasovagal]] |
| ! Preferred use
| |
| ! Preferably combined with
| |
| |-
| |
| | [[Thiazide diuretics]] || [[Chlorthalidone]] || 12.5, 12.5-25|| [[Heart failure]], [[systolic hypertension|isolated systolic hypertension]], black population|| [[ACE inhibitors]], [[ARBs]], [[calcium channel blockers]]
| |
| |-
| |
| | || [[Hydrochlorothiazide]] || 12.5-25, 25-100
| |
| |-
| |
| | || [[Bendroflumethiazide]] || 5, 10
| |
| |-
| |
| | || [[Indapamide]] || 1.25, 1.25-2.5
| |
| |-
| |
| | [[ACE inhibitors]] || [[Enalapril]] || 5, 20|| [[Left ventricular hypertrophy]], [[atherosclerosis]], [[renal insufficiency]], previous [[myocardial infarction]], [[heart failure]], [[atrial fibrillation]] (prevention), [[peripheral artery disease]], [[metabolic syndrome]], [[diabetes mellitus]]|| [[Calcium channel blockers]], [[thiazide diuretics]]
| |
| |-
| |
| | || [[Lisinopril]] || 10, 40
| |
| |-
| |
| | || [[Captopril]] || 50, 150-200
| |
| |-
| |
| | [[ARBs]] || [[Candesartan]] || 4, 12-32|| [[Left ventricular hypertrophy]], [[renal insufficiency]], previous [[myocardial infarction]], [[heart failure]], [[atrial fibrillation]] (prevention), [[metabolic syndrome]], [[diabetes mellitus]]|| [[Calcium channel blockers]], [[thiazide diuretics]]
| |
| |-
| |
| | || [[Losartan]] || 50, 100
| |
| |-
| |
| | || [[Valsartan]] || 40-80, 160-320
| |
| |-
| |
| | || [[Eprosartan]] || 400, 600-800
| |
| |-
| |
| | || [[Irbesartan]] || 75, 300
| |
| |-
| |
| | [[Beta blockers]] || [[Atenolol]] || 25-50, 100|| Previous [[myocardial infarction]], [[atrial fibrillation]] (prevention and ventricular rate control), [[heart failure]], [[Chronic stable angina|angina pectoris]], [[aortic aneurysm]], [[pregnancy]]|| [[Thiazide diuretics]] (with limitations)<br>'''Only [[Calcium channel blocker#Dihydropyridine|dihydropyridine calcium channel blockers]] should be combined with [[beta blockers]]'''
| |
| |-
| |
| | || [[Metoprolol succinate]] || 50, 100-200
| |
| |-
| |
| | [[Calcium channel blockers]]|| [[Amlodipine]] || 2.5, 10|| [[Left ventricular hypertrophy]], [[pregnancy]] ([[nifedipine]]), previous [[myocardial infarction]], [[atrial fibrillation]] ([[verapamil]], [[diltiazem]]), [[metabolic syndrome]], [[peripheral artery disease]], [[atherosclerosis]], [[Chronic stable angina|angina pectoris]], [[systolic hypertension|isolated systolic hypertension]], black population|| [[ACE inhibitors]], [[ARBs]], [[thiazide diuretics]]
| |
| |-
| |
| | || [[Diltiazem extended release]] || 120-180, 360
| |
| |-
| |
| | || [[Nitrendipine]] || 10, 20
| |
| |-
| |
| |}
| |