Dermatitis herpetiformis natural history, complications and prognosis: Difference between revisions
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==Overview== | |||
Dermatitis Herpetiformis (also called [[Duhring's disease]]), is a chronic itchy rash which is frequently associated with [[Celiac Disease]]. The rash is made of [[papules]] and [[vesicles]] which are present on different parts of the body mostly commonly on neck, trunk, buttocks and knees. It is an [[autoimmune]] mediated skin condition, which is IgA mediated reaction and is associated with [[gluten sensitivity]] of small bowel. There is presence of [[antibodies]] which leads to positive serology test results. | |||
Dermatitis herpetiformis is associated with high prevalence of other [[autoimmune diseases]]. | |||
==Natural History== | ==Natural History== | ||
This chronic rash is rarely widely distributed. The vesicles on the rash are rare to be noticed because of intense itching which is relieved with scratching and rupture of the vesicles. The rash can be controlled with the use of antibiotic and gluten free diet. | This chronic rash is rarely widely distributed. The vesicles on the rash are rare to be noticed because of intense itching which is relieved with scratching and rupture of the vesicles. The rash can be controlled with the use of antibiotic and gluten free diet. | ||
==Complications== | ==Complications== | ||
Thyroid disease may be found in many patients with dermatitis herpetiformis. Patients are also more likely to develop certain cancers of the intestines. | Thyroid disease may be found in many patients with dermatitis herpetiformis. Patients are also more likely to develop certain cancers of the intestines. | ||
==Prognosis== | ==Prognosis== | ||
Latest revision as of 00:58, 7 February 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Dermatitis Herpetiformis (also called Duhring's disease), is a chronic itchy rash which is frequently associated with Celiac Disease. The rash is made of papules and vesicles which are present on different parts of the body mostly commonly on neck, trunk, buttocks and knees. It is an autoimmune mediated skin condition, which is IgA mediated reaction and is associated with gluten sensitivity of small bowel. There is presence of antibodies which leads to positive serology test results.
Dermatitis herpetiformis is associated with high prevalence of other autoimmune diseases.
Natural History
This chronic rash is rarely widely distributed. The vesicles on the rash are rare to be noticed because of intense itching which is relieved with scratching and rupture of the vesicles. The rash can be controlled with the use of antibiotic and gluten free diet.
Complications
Thyroid disease may be found in many patients with dermatitis herpetiformis. Patients are also more likely to develop certain cancers of the intestines.
Prognosis
The disease may be well controlled with treatment. Without treatment, there may be a significant risk of intestinal cancer.[1]