Thrombophilia risk factors: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Thrombophilia}} | {{Thrombophilia}} | ||
{{CMG}} {{AE}} {{asiri}} | {{CMG}} {{AE}} {{asiri}} {{JK}} | ||
==Overview== | ==Overview== | ||
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**Family history of inherited thrombophilia | **Family history of inherited thrombophilia | ||
*Risk factors in the development of '''acquired thrombophlias''' are enlisted in the following Table 1: | *Risk factors in the development of '''acquired thrombophlias''' are enlisted in the following '''Table 1''': <ref name="urlAcute Pulmonary Embolism Article">{{cite web |url=https://www.statpearls.com/ArticleLibrary/viewarticle/42576 |title=Acute Pulmonary Embolism Article |format= |work= |accessdate=}}</ref> | ||
{| class="wikitable" | {| class="wikitable" | ||
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*[[Age]] | *Advancing [[Age]] | ||
*[[Pregnancy]] | *[[Pregnancy]] | ||
*[[Oral_contraceptive|Oral contraceptive pills]] | *[[Oral_contraceptive|Oral contraceptive pills]] | ||
*[[Hormone_replacement_therapy|Hormone therapy]] | *[[Hormone_replacement_therapy|Hormone therapy]] | ||
*Postpartum period | *Postpartum period | ||
*Infection (specifically pneumonia, urinary tract infection, and HIV) | *[[Infection]] (specifically pneumonia, urinary tract infection, and HIV) | ||
*Cancer (highest risk in metastatic disease) | *[[Cancer]] (highest risk in metastatic disease) | ||
*Bed rest greater than three days | *Bed rest greater than three days | ||
*[[Obesity]] | *[[Obesity]] | ||
|| | || | ||
*[[Immobility]] | *[[Immobility]] | ||
*Fracture of lower limb | *[[Fracture]] of [[lower limb]] | ||
*Hospitalization for heart failure or atrial fibrillation/flutter within the previous three months | *Hospitalization for [[heart failure]] or [[atrial fibrillation]]/flutter within the previous three months | ||
*Hip or knee replacement | *Hip or knee replacement | ||
*Major trauma | *Major trauma | ||
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*Central venous lines | *Central venous lines | ||
*Chemotherapy | *Chemotherapy | ||
*Congestive heart failure or respiratory failure | *[[Congestive heart failure]] or respiratory failure | ||
|} | |} | ||
==References== | ==References== | ||
Latest revision as of 17:54, 5 April 2021
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Thrombophilia risk factors On the Web |
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Risk calculators and risk factors for Thrombophilia risk factors |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Asiri Ediriwickrema, M.D., M.H.S. [2] Jaspinder Kaur, MBBS[3]
Overview
Common risk factors in the development of acquired thrombophlias are trauma, surgery, immobility, pregnancy, oral contraceptives, hormone replacement therapy, and age. Common risk factors for the development of inherited thrombophilias are a family history of thrombosis at an early age or a family history of inherited thrombophilia. Common genetic risk factors in the development of inherited thrombophilias are mutations in factor V leiden and prothrombin G20210A.
Risk Factors
- Risk factors for inherited thrombophilias are as follows:[1][2][3]
- Family history of thrombosis at an early age
- Family history of inherited thrombophilia
- Risk factors in the development of acquired thrombophlias are enlisted in the following Table 1: [4]
| Acquired risk factors | Acquired risk factors |
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References
- ↑ Cohoon KP, Heit JA (2014). "Inherited and secondary thrombophilia". Circulation. 129 (2): 254–7. doi:10.1161/CIRCULATIONAHA.113.001943. PMC 3979345. PMID 24421360.
- ↑ Seligsohn U, Lubetsky A (2001). "Genetic susceptibility to venous thrombosis". N Engl J Med. 344 (16): 1222–31. doi:10.1056/NEJM200104193441607. PMID 11309638.
- ↑ Middeldorp S (2011). "Evidence-based approach to thrombophilia testing". J Thromb Thrombolysis. 31 (3): 275–81. doi:10.1007/s11239-011-0572-y. PMC 3056012. PMID 21340752.
- ↑ "Acute Pulmonary Embolism Article".