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==Overview==
==Overview==
[[Alcoholic hepatitis]] was first recognized in 1961 after investigation of 7 cases with excessive [[alcohol]] intake . Before the recognition of [[Alcoholic Hepatitis]], it was believed that the [[symptoms]] are caused by [[malnutrition]] not due to toxic effects of [[alcohol]]. Charles S. Lieber developed modern research on alcohol-related [[liver disease]].


==Historical Perspective==


==Historical Perspective==
*In 1950s, it was believed that [[alcohol-related]] [[liver damage]] is due to [[malnutrition]] rather than toxic effects of [[alcohol]].<ref name="NeumanCohen2014">{{cite journal|last1=Neuman|first1=M. G.|last2=Cohen|first2=L.|last3=Zakhari|first3=S.|last4=Nanau|first4=R. M.|last5=Mueller|first5=S.|last6=Schneider|first6=M.|last7=Parry|first7=C.|last8=Isip|first8=R.|last9=Seitz|first9=H. K.|title=Alcoholic Liver Disease: A Synopsis of the Charles Lieber's Memorial Symposia 2009-2012|journal=Alcohol and Alcoholism|volume=49|issue=4|year=2014|pages=373–380|issn=0735-0414|doi=10.1093/alcalc/agu021}}</ref>
* Charles S. Lieber was the first one who developed modern research on alcohol and alcohol-related liver damage.<ref name="NeumanCohen2014">{{cite journal|last1=Neuman|first1=M. G.|last2=Cohen|first2=L.|last3=Zakhari|first3=S.|last4=Nanau|first4=R. M.|last5=Mueller|first5=S.|last6=Schneider|first6=M.|last7=Parry|first7=C.|last8=Isip|first8=R.|last9=Seitz|first9=H. K.|title=Alcoholic Liver Disease: A Synopsis of the Charles Lieber's Memorial Symposia 2009-2012|journal=Alcohol and Alcoholism|volume=49|issue=4|year=2014|pages=373–380|issn=0735-0414|doi=10.1093/alcalc/agu021}}</ref>
*In 1961, Beckett and his colleagues used the term [[Alcoholic Hepatitis]] for the first time.<ref name="BeckettLivingstone1961">{{cite journal|last1=Beckett|first1=A. G.|last2=Livingstone|first2=A. V.|last3=Hill|first3=K. R.|title=Acute Alcoholic Hepatitis|journal=BMJ|volume=2|issue=5260|year=1961|pages=1113–1119|issn=0959-8138|doi=10.1136/bmj.2.5260.1113}}</ref>
*Beckett et al. investigated 7 cases of acute [[Alcoholic Hepatitis]] and their features at Royal Free Hospital in Great Britain during 1953-1961.<ref name="BeckettLivingstone1961">{{cite journal|last1=Beckett|first1=A. G.|last2=Livingstone|first2=A. V.|last3=Hill|first3=K. R.|title=Acute Alcoholic Hepatitis|journal=BMJ|volume=2|issue=5260|year=1961|pages=1113–1119|issn=0959-8138|doi=10.1136/bmj.2.5260.1113}}</ref>
*Charles S. Lieber was the first one who developed modern research on [[alcohol]] and [[alcohol-related]] [[liver damage]].<ref name="NeumanCohen2014">{{cite journal|last1=Neuman|first1=M. G.|last2=Cohen|first2=L.|last3=Zakhari|first3=S.|last4=Nanau|first4=R. M.|last5=Mueller|first5=S.|last6=Schneider|first6=M.|last7=Parry|first7=C.|last8=Isip|first8=R.|last9=Seitz|first9=H. K.|title=Alcoholic Liver Disease: A Synopsis of the Charles Lieber's Memorial Symposia 2009-2012|journal=Alcohol and Alcoholism|volume=49|issue=4|year=2014|pages=373–380|issn=0735-0414|doi=10.1093/alcalc/agu021}}</ref>


==References==
==References==

Latest revision as of 21:03, 29 July 2021

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shadan Mehraban, M.D.[2]

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Overview

Alcoholic hepatitis was first recognized in 1961 after investigation of 7 cases with excessive alcohol intake . Before the recognition of Alcoholic Hepatitis, it was believed that the symptoms are caused by malnutrition not due to toxic effects of alcohol. Charles S. Lieber developed modern research on alcohol-related liver disease.

Historical Perspective

References

  1. 1.0 1.1 Neuman, M. G.; Cohen, L.; Zakhari, S.; Nanau, R. M.; Mueller, S.; Schneider, M.; Parry, C.; Isip, R.; Seitz, H. K. (2014). "Alcoholic Liver Disease: A Synopsis of the Charles Lieber's Memorial Symposia 2009-2012". Alcohol and Alcoholism. 49 (4): 373–380. doi:10.1093/alcalc/agu021. ISSN 0735-0414.
  2. 2.0 2.1 Beckett, A. G.; Livingstone, A. V.; Hill, K. R. (1961). "Acute Alcoholic Hepatitis". BMJ. 2 (5260): 1113–1119. doi:10.1136/bmj.2.5260.1113. ISSN 0959-8138.

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