Gangrene natural history, complications and prognosis: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Gangrene}} | {{Gangrene}} | ||
{{CMG}}; {{AE}} [[User:Edzelco|Edzel Lorraine Co, D.M.D., M.D.]] | {{CMG}}; {{AE}} [[User:Edzelco|Edzel Lorraine Co, D.M.D., M.D.]] | ||
==Overview== | ==Overview== | ||
[[Amputation]] and [[death]] are the most common consequence of [[critical limb ischemia]]/ [[chronic limb-threatening ischemia]]. <ref name="pmid25439329">{{cite journal| author=Elsayed S, Clavijo LC| title=Critical limb ischemia. | journal=Cardiol Clin | year= 2015 | volume= 33 | issue= 1 | pages= 37-47 | pmid=25439329 | doi=10.1016/j.ccl.2014.09.008 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25439329 }} </ref> [[Gas gangrene]] has a higher [[fatality rate]], ranging from 25% | [[Amputation]] and [[death]] are the most common consequence of [[critical limb ischemia]]/ [[chronic limb-threatening ischemia]]. <ref name="pmid25439329">{{cite journal| author=Elsayed S, Clavijo LC| title=Critical limb ischemia. | journal=Cardiol Clin | year= 2015 | volume= 33 | issue= 1 | pages= 37-47 | pmid=25439329 | doi=10.1016/j.ccl.2014.09.008 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25439329 }} </ref> [[Gas gangrene]] has a higher [[fatality rate]], ranging from 25% to 100%, if [[treatment]] is inadequate or delayed. Increased [[age]], several [[comorbidities]] present, and involvement of [[trunk]] lead to a poor [[prognosis]]. <ref name="pmid26631369">{{cite journal| author=Yang Z, Hu J, Qu Y, Sun F, Leng X, Li H | display-authors=etal| title=Interventions for treating gas gangrene. | journal=Cochrane Database Syst Rev | year= 2015 | volume= | issue= 12 | pages= CD010577 | pmid=26631369 | doi=10.1002/14651858.CD010577.pub2 | pmc=8652263 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26631369 }} </ref> | ||
==Complications== | ==Complications== | ||
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*There is a possibility of [[recurrence]] of [[critical limb ischemia]]/ [[chronic limb-threatening ischemia]]. | *There is a possibility of [[recurrence]] of [[critical limb ischemia]]/ [[chronic limb-threatening ischemia]]. | ||
*Follow-up after [[revascularization procedures]] is needed for at least two years.<ref name="pmid31159978">{{cite journal| author=Conte MS, Bradbury AW, Kolh P, White JV, Dick F, Fitridge R | display-authors=etal| title=Global vascular guidelines on the management of chronic limb-threatening ischemia. | journal=J Vasc Surg | year= 2019 | volume= 69 | issue= 6S | pages= 3S-125S.e40 | pmid=31159978 | doi=10.1016/j.jvs.2019.02.016 | pmc=8365864 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31159978 }} </ref> | *Follow-up after [[revascularization procedures]] is needed for at least two years.<ref name="pmid31159978">{{cite journal| author=Conte MS, Bradbury AW, Kolh P, White JV, Dick F, Fitridge R | display-authors=etal| title=Global vascular guidelines on the management of chronic limb-threatening ischemia. | journal=J Vasc Surg | year= 2019 | volume= 69 | issue= 6S | pages= 3S-125S.e40 | pmid=31159978 | doi=10.1016/j.jvs.2019.02.016 | pmc=8365864 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31159978 }} </ref> | ||
*[[Gas gangrene]] has higher [[fatality rate]], ranging from 25% | *[[Gas gangrene]] has higher [[fatality rate]], ranging from 25% to 100%, if [[treatment]] is inadequate or delayed. | ||
*Increased [[age]], several [[comorbidities]] present, and involvement of [[trunk]] lead to a poor [[prognosis]]. <ref name="pmid26631369">{{cite journal| author=Yang Z, Hu J, Qu Y, Sun F, Leng X, Li H | display-authors=etal| title=Interventions for treating gas gangrene. | journal=Cochrane Database Syst Rev | year= 2015 | volume= | issue= 12 | pages= CD010577 | pmid=26631369 | doi=10.1002/14651858.CD010577.pub2 | pmc=8652263 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26631369 }} </ref> | *Increased [[age]], several [[comorbidities]] present, and involvement of [[trunk]] lead to a poor [[prognosis]]. <ref name="pmid26631369">{{cite journal| author=Yang Z, Hu J, Qu Y, Sun F, Leng X, Li H | display-authors=etal| title=Interventions for treating gas gangrene. | journal=Cochrane Database Syst Rev | year= 2015 | volume= | issue= 12 | pages= CD010577 | pmid=26631369 | doi=10.1002/14651858.CD010577.pub2 | pmc=8652263 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26631369 }} </ref> | ||
==References== | ==References== | ||
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[[Category:Emergency medicine]] | [[Category:Emergency medicine]] | ||
[[Category:Intensive care medicine]] | [[Category:Intensive care medicine]] | ||
[[Category: | [[Category:Up to Date]] | ||
Latest revision as of 20:15, 28 April 2022
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Edzel Lorraine Co, D.M.D., M.D.
Overview
Amputation and death are the most common consequence of critical limb ischemia/ chronic limb-threatening ischemia. [1] Gas gangrene has a higher fatality rate, ranging from 25% to 100%, if treatment is inadequate or delayed. Increased age, several comorbidities present, and involvement of trunk lead to a poor prognosis. [2]
Complications
- Amputation and death are the most common consequence of critical limb ischemia/ chronic limb-threatening ischemia. [1]
- Below-the-knee amputations lead to a higher ambulatory rate than above-the-knee amputations.[3]
Prognosis
- There is a possibility of recurrence of critical limb ischemia/ chronic limb-threatening ischemia.
- Follow-up after revascularization procedures is needed for at least two years.[4]
- Gas gangrene has higher fatality rate, ranging from 25% to 100%, if treatment is inadequate or delayed.
- Increased age, several comorbidities present, and involvement of trunk lead to a poor prognosis. [2]
References
- ↑ 1.0 1.1 Elsayed S, Clavijo LC (2015). "Critical limb ischemia". Cardiol Clin. 33 (1): 37–47. doi:10.1016/j.ccl.2014.09.008. PMID 25439329.
- ↑ 2.0 2.1 Yang Z, Hu J, Qu Y, Sun F, Leng X, Li H; et al. (2015). "Interventions for treating gas gangrene". Cochrane Database Syst Rev (12): CD010577. doi:10.1002/14651858.CD010577.pub2. PMC 8652263 Check
|pmc=value (help). PMID 26631369. - ↑ Landry GJ (2007). "Functional outcome of critical limb ischemia". J Vasc Surg. 45 Suppl A: A141–8. doi:10.1016/j.jvs.2007.02.052. PMID 17544035.
- ↑ Conte MS, Bradbury AW, Kolh P, White JV, Dick F, Fitridge R; et al. (2019). "Global vascular guidelines on the management of chronic limb-threatening ischemia". J Vasc Surg. 69 (6S): 3S–125S.e40. doi:10.1016/j.jvs.2019.02.016. PMC 8365864 Check
|pmc=value (help). PMID 31159978.