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{{Cardiac tumors}}
{{Cardiac tumors}}


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{{CMG}}; {{AE}} {{DMakkar}}


: [Cardiac Tumors] were first described by [Realdo Colombo] in [1559].<ref name="pmid1417305">{{cite journal| author=Chitwood WR| title=Clarence Crafoord and the first successful resection of a cardiac myxoma. | journal=Ann Thorac Surg | year= 1992 | volume= 54 | issue= 5 | pages= 997-8 | pmid=1417305 | doi=10.1016/0003-4975(92)90676-u | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1417305  }} </ref>
==Overview==
*In [1936], [Beck and Maurer] were the first to resect right [[ventricular teratoma]]. They also resected a left [[ventricular lipoma]] in 1951.<ref name="pmid17858078">{{cite journal| author=Beck CS| title=AN INTRAPERICARDIAL TERATOMA AND A TUMOR OF THE HEART: BOTH REMOVED OPERATIVELY. | journal=Ann Surg | year= 1942 | volume= 116 | issue= 2 | pages= 161-74 | pmid=17858078 | doi=10.1097/00000658-194208000-00001 | pmc=1543811 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17858078  }} </ref>
* Realdo Colombo initially reported cardiac tumors in 1559, and Dr. Clarence Crafoord performed the first successful surgical resection of left atrial myxoma in 1954. New chemotherapy drugs and treatment have been developing after the discovery of cardiac tumors.
*In [1952], [[left atrial myxoma]] was successfully excised by [Bahnson and Newman] through a [[right atriotomy]]. Unfortunately, the patient succumbed to the procedure after 24 days.<ref name="pmid13094264">{{cite journal| author=BAHNSON HT, NEWMAN EV| title=Diagnosis and surgical removal of intracavitary myxoma of the right atrium. | journal=Bull Johns Hopkins Hosp | year= 1953 | volume= 93 | issue= 3 | pages= 150-63 | pmid=13094264 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=13094264  }} </ref>


==Historical Perspective==


*Cardiac Tumors were first described by Realdo Colombo in 1559.<ref name="pmid1417305">{{cite journal| author=Chitwood WR| title=Clarence Crafoord and the first successful resection of a cardiac myxoma. | journal=Ann Thorac Surg | year= 1992 | volume= 54 | issue= 5 | pages= 997-8 | pmid=1417305 | doi=10.1016/0003-4975(92)90676-u | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1417305  }} </ref>
*In 1936, Beck and Maurer were the first to resect right [[ventricular teratoma]]. They also resected a left [[ventricular lipoma]] in 1951.<ref name="pmid17858078">{{cite journal| author=Beck CS| title=AN INTRAPERICARDIAL TERATOMA AND A TUMOR OF THE HEART: BOTH REMOVED OPERATIVELY. | journal=Ann Surg | year= 1942 | volume= 116 | issue= 2 | pages= 161-74 | pmid=17858078 | doi=10.1097/00000658-194208000-00001 | pmc=1543811 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17858078  }} </ref>
*Dr. William Norris was the first to describe a "melanotic heart" with secondary metastases to the heart in 1820.<ref name="pmid9921977">{{cite journal| author=Gibbs P, Cebon JS, Calafiore P, Robinson WA| title=Cardiac metastases from malignant melanoma. | journal=Cancer | year= 1999 | volume= 85 | issue= 1 | pages= 78-84 | pmid=9921977 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9921977  }} </ref>
*In 1952, [[left atrial myxoma]] was successfully excised by Bahnson and Newman through a [[right atriotomy]]. Unfortunately, the patient succumbed to the procedure after 24 days.<ref name="pmid13094264">{{cite journal| author=BAHNSON HT, NEWMAN EV| title=Diagnosis and surgical removal of intracavitary myxoma of the right atrium. | journal=Bull Johns Hopkins Hosp | year= 1953 | volume= 93 | issue= 3 | pages= 150-63 | pmid=13094264 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=13094264  }} </ref>
===Landmark events in the development of treatment strategies===
*In 1954, Dr. Clarence Crafoord from Sweden reported the first successful removal of [[left atrial myxoma]] in a 40-year-old female presenting with [[dizziness]] and [[transient hemiparesis]] caused by [[myxoma]].The patient survived for more than 40 years after her surgery.<ref name="pmid1417305">{{cite journal| author=Chitwood WR| title=Clarence Crafoord and the first successful resection of a cardiac myxoma. | journal=Ann Thorac Surg | year= 1992 | volume= 54 | issue= 5 | pages= 997-8 | pmid=1417305 | doi=10.1016/0003-4975(92)90676-u | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1417305  }} </ref>
*Dr. Senning and his team developed [[Extracorporeal|perfusion system]] to ease cardiac surgeries. The [[Extracorporeal|Perfusion system]] comprised of [[perfusion|hypothermia]], [[decreased|flow]], and [[ventricular fibrillation]] to prevent [[air|embolism]].<ref name="pmid1417305">{{cite journal| author=Chitwood WR| title=Clarence Crafoord and the first successful resection of a cardiac myxoma. | journal=Ann Thorac Surg | year= 1992 | volume= 54 | issue= 5 | pages= 997-8 | pmid=1417305 | doi=10.1016/0003-4975(92)90676-u | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1417305  }} </ref>
* In July 1954, they used it for the first time in the excision of [[left atrial myxoma]], performed by Dr. Crafoord. This was a milestone surgery in developing [[Extracorporeal perfusion system]].<ref name="pmid1417305">{{cite journal| author=Chitwood WR| title=Clarence Crafoord and the first successful resection of a cardiac myxoma. | journal=Ann Thorac Surg | year= 1992 | volume= 54 | issue= 5 | pages= 997-8 | pmid=1417305 | doi=10.1016/0003-4975(92)90676-u | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1417305  }} </ref>


==References==
==References==
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Latest revision as of 19:58, 4 July 2022

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dheeraj Makkar, M.D.[2]

Overview

  • Realdo Colombo initially reported cardiac tumors in 1559, and Dr. Clarence Crafoord performed the first successful surgical resection of left atrial myxoma in 1954. New chemotherapy drugs and treatment have been developing after the discovery of cardiac tumors.

Historical Perspective

  • Cardiac Tumors were first described by Realdo Colombo in 1559.[1]
  • In 1936, Beck and Maurer were the first to resect right ventricular teratoma. They also resected a left ventricular lipoma in 1951.[2]
  • Dr. William Norris was the first to describe a "melanotic heart" with secondary metastases to the heart in 1820.[3]
  • In 1952, left atrial myxoma was successfully excised by Bahnson and Newman through a right atriotomy. Unfortunately, the patient succumbed to the procedure after 24 days.[4]

Landmark events in the development of treatment strategies

References

  1. 1.0 1.1 1.2 1.3 Chitwood WR (1992). "Clarence Crafoord and the first successful resection of a cardiac myxoma". Ann Thorac Surg. 54 (5): 997–8. doi:10.1016/0003-4975(92)90676-u. PMID 1417305.
  2. Beck CS (1942). "AN INTRAPERICARDIAL TERATOMA AND A TUMOR OF THE HEART: BOTH REMOVED OPERATIVELY". Ann Surg. 116 (2): 161–74. doi:10.1097/00000658-194208000-00001. PMC 1543811. PMID 17858078.
  3. Gibbs P, Cebon JS, Calafiore P, Robinson WA (1999). "Cardiac metastases from malignant melanoma". Cancer. 85 (1): 78–84. PMID 9921977.
  4. BAHNSON HT, NEWMAN EV (1953). "Diagnosis and surgical removal of intracavitary myxoma of the right atrium". Bull Johns Hopkins Hosp. 93 (3): 150–63. PMID 13094264.

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