Sudden cardiac death (patient information): Difference between revisions
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==When to seek urgent medical care?== | ==When to seek urgent medical care?== | ||
* Evaluation of [[SCD]] decedents is recommended for: | |||
**First degree relatives of [[patients]] who suffered [[SCD]] | |||
**Relatives who have [[inherited]] the [[genetic mutation]] based on the [[family history]] analysis | |||
**Relatives who possess [[symptoms]] of [[SCD]] <ref name="pmid20646679">{{cite journal| author=van der Werf C, Hofman N, Tan HL, van Dessel PF, Alders M, van der Wal AC | display-authors=etal| title=Diagnostic yield in sudden unexplained death and aborted cardiac arrest in the young: the experience of a tertiary referral center in The Netherlands. | journal=Heart Rhythm | year= 2010 | volume= 7 | issue= 10 | pages= 1383-9 | pmid=20646679 | doi=10.1016/j.hrthm.2010.05.036 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20646679 }} </ref> <ref name="pmid14602442">{{cite journal| author=Behr E, Wood DA, Wright M, Syrris P, Sheppard MN, Casey A | display-authors=etal| title=Cardiological assessment of first-degree relatives in sudden arrhythmic death syndrome. | journal=Lancet | year= 2003 | volume= 362 | issue= 9394 | pages= 1457-9 | pmid=14602442 | doi=10.1016/s0140-6736(03)14692-2 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14602442 }} </ref> <ref name="pmid15998675">{{cite journal| author=Tan HL, Hofman N, van Langen IM, van der Wal AC, Wilde AA| title=Sudden unexplained death: heritability and diagnostic yield of cardiological and genetic examination in surviving relatives. | journal=Circulation | year= 2005 | volume= 112 | issue= 2 | pages= 207-13 | pmid=15998675 | doi=10.1161/CIRCULATIONAHA.104.522581 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15998675 }} </ref> <ref name="pmid18508782">{{cite journal| author=Behr ER, Dalageorgou C, Christiansen M, Syrris P, Hughes S, Tome Esteban MT | display-authors=etal| title=Sudden arrhythmic death syndrome: familial evaluation identifies inheritable heart disease in the majority of families. | journal=Eur Heart J | year= 2008 | volume= 29 | issue= 13 | pages= 1670-80 | pmid=18508782 | doi=10.1093/eurheartj/ehn219 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18508782 }} </ref> <ref name="pmid29544603">{{cite journal| author=Papadakis M, Papatheodorou E, Mellor G, Raju H, Bastiaenen R, Wijeyeratne Y | display-authors=etal| title=The Diagnostic Yield of Brugada Syndrome After Sudden Death With Normal Autopsy. | journal=J Am Coll Cardiol | year= 2018 | volume= 71 | issue= 11 | pages= 1204-1214 | pmid=29544603 | doi=10.1016/j.jacc.2018.01.031 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29544603 }} </ref>. | |||
==Treatment options== | ==Treatment options== | ||
| Line 55: | Line 57: | ||
==Prevention== | ==Prevention== | ||
* Application of [[ICD]] are helpful in minimizing the risk for [[SCD]] | * Application of [[ICD]] are helpful in minimizing the risk for [[SCD]] <ref name="pmid26464886">{{cite journal| author=Higgins JP, Andino A| title=Soccer and Sudden Cardiac Death in Young Competitive Athletes: A Review. | journal=J Sports Med (Hindawi Publ Corp) | year= 2013 | volume= 2013 | issue= | pages= 967183 | pmid=26464886 | doi=10.1155/2013/967183 | pmc=4590894 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26464886 }} </ref>. | ||
<ref name="pmid26464886">{{cite journal| author=Higgins JP, Andino A| title=Soccer and Sudden Cardiac Death in Young Competitive Athletes: A Review. | journal=J Sports Med (Hindawi Publ Corp) | year= 2013 | volume= 2013 | issue= | pages= 967183 | pmid=26464886 | doi=10.1155/2013/967183 | pmc=4590894 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26464886 }} </ref> | * [[Cardiac screening]] for [[hypertrophic cardiomyopathy]] ([[HCM]]) among athletes is necessary prior to active participation in sports as [[HCM]] is most commonly associated with [[SCD]] in young adults. | ||
==What to expect (Outlook/Prognosis)?== | ==What to expect (Outlook/Prognosis)?== | ||
* Poor [[neurological]] outcomes are expected in patients who survived [[SCA]] <ref name="pmid32406999">{{cite journal| author=Lotfi A, Klein LW, Hira RS, Mallidi J, Mehran R, Messenger JC | display-authors=etal| title=SCAI expert consensus statement on out of hospital cardiac arrest. | journal=Catheter Cardiovasc Interv | year= 2020 | volume= 96 | issue= 4 | pages= 844-861 | pmid=32406999 | doi=10.1002/ccd.28990 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=32406999 }} </ref>. | |||
== | |||
==Sources== | ==Sources== | ||
Latest revision as of 18:52, 19 July 2023
For the WikiDoc page for this topic, click here
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Edzel Lorraine Co, D.M.D., M.D.
Overview
- Sudden cardiac death arises when the heart suddenly stops and not given prompt treatment. This happens because a problem occurs with the electrical system of the heart.
What are the symptoms of sudden cardiac death?
- Patients with sudden cardiac death can experience:
What causes sudden cardiac death?
Some medical problems that could cause sudden cardiac death include:
- Thickening of the heart muscles
- Electrical conduction problem of the heart
- Lung problems
- Illegal use of drugs such as cocaine, methamphetamine, or heroin
- Electrolyte problems
Who is at highest risk?
- Patients with ongoing heart problems are at high risk of experiencing sudden cardiac death.
- This include:
Diagnosis
- Cardiac monitoring must be done to patients who arrive in emergency department for evaluation of sudden cardiac arrest (SCA0. Full cardiac assessment is carried out to patients who survive SCA and these tests include:
- Right after a sudden death, autopsy and genetic testing] are done to determine the cause of death.
- For a more specific diagnosis, further workup such as toxicology screen, chemistry and microbiology workup are done [2] [3].
When to seek urgent medical care?
- Evaluation of SCD decedents is recommended for:
Treatment options
- The main goal in treatment is to prevent sudden cardiac death (SCD. Options include the use of medications, implantable cardioverter defibrillators (ICD), and catheter ablation [9] [10] [11] [12] [13] [14] [15]
Prevention
- Application of ICD are helpful in minimizing the risk for SCD [16].
- Cardiac screening for hypertrophic cardiomyopathy (HCM) among athletes is necessary prior to active participation in sports as HCM is most commonly associated with SCD in young adults.
What to expect (Outlook/Prognosis)?
- Poor neurological outcomes are expected in patients who survived SCA [17].
Sources
- ↑ Katritsis DG, Gersh BJ, Camm AJ (2016). "A Clinical Perspective on Sudden Cardiac Death". Arrhythm Electrophysiol Rev. 5 (3): 177–182. doi:10.15420/aer.2016:11:2. PMC 5248660. PMID 28116082.
- ↑ Bagnall RD, Weintraub RG, Ingles J, Duflou J, Yeates L, Lam L; et al. (2016). "A Prospective Study of Sudden Cardiac Death among Children and Young Adults". N Engl J Med. 374 (25): 2441–52. doi:10.1056/NEJMoa1510687. PMID 27332903.
- ↑ Basso C, Aguilera B, Banner J, Cohle S, d'Amati G, de Gouveia RH; et al. (2017). "Guidelines for autopsy investigation of sudden cardiac death: 2017 update from the Association for European Cardiovascular Pathology". Virchows Arch. 471 (6): 691–705. doi:10.1007/s00428-017-2221-0. PMC 5711979. PMID 28889247.
- ↑ van der Werf C, Hofman N, Tan HL, van Dessel PF, Alders M, van der Wal AC; et al. (2010). "Diagnostic yield in sudden unexplained death and aborted cardiac arrest in the young: the experience of a tertiary referral center in The Netherlands". Heart Rhythm. 7 (10): 1383–9. doi:10.1016/j.hrthm.2010.05.036. PMID 20646679.
- ↑ Behr E, Wood DA, Wright M, Syrris P, Sheppard MN, Casey A; et al. (2003). "Cardiological assessment of first-degree relatives in sudden arrhythmic death syndrome". Lancet. 362 (9394): 1457–9. doi:10.1016/s0140-6736(03)14692-2. PMID 14602442.
- ↑ Tan HL, Hofman N, van Langen IM, van der Wal AC, Wilde AA (2005). "Sudden unexplained death: heritability and diagnostic yield of cardiological and genetic examination in surviving relatives". Circulation. 112 (2): 207–13. doi:10.1161/CIRCULATIONAHA.104.522581. PMID 15998675.
- ↑ Behr ER, Dalageorgou C, Christiansen M, Syrris P, Hughes S, Tome Esteban MT; et al. (2008). "Sudden arrhythmic death syndrome: familial evaluation identifies inheritable heart disease in the majority of families". Eur Heart J. 29 (13): 1670–80. doi:10.1093/eurheartj/ehn219. PMID 18508782.
- ↑ Papadakis M, Papatheodorou E, Mellor G, Raju H, Bastiaenen R, Wijeyeratne Y; et al. (2018). "The Diagnostic Yield of Brugada Syndrome After Sudden Death With Normal Autopsy". J Am Coll Cardiol. 71 (11): 1204–1214. doi:10.1016/j.jacc.2018.01.031. PMID 29544603.
- ↑ Mazzanti A, Maragna R, Faragli A, Monteforte N, Bloise R, Memmi M; et al. (2016). "Gene-Specific Therapy With Mexiletine Reduces Arrhythmic Events in Patients With Long QT Syndrome Type 3". J Am Coll Cardiol. 67 (9): 1053–1058. doi:10.1016/j.jacc.2015.12.033. PMC 4773513. PMID 26940925.
- ↑ Watanabe H, Chopra N, Laver D, Hwang HS, Davies SS, Roach DE; et al. (2009). "Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans". Nat Med. 15 (4): 380–3. doi:10.1038/nm.1942. PMC 2904954. PMID 19330009.
- ↑ Echt DS, Liebson PR, Mitchell LB, Peters RW, Obias-Manno D, Barker AH; et al. (1991). "Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial". N Engl J Med. 324 (12): 781–8. doi:10.1056/NEJM199103213241201. PMID 1900101.
- ↑ Greene HL, Roden DM, Katz RJ, Woosley RL, Salerno DM, Henthorn RW (1992). "The Cardiac Arrhythmia Suppression Trial: first CAST ... then CAST-II". J Am Coll Cardiol. 19 (5): 894–8. doi:10.1016/0735-1097(92)90267-q. PMID 1552108.
- ↑ van Welsenes GH, van Rees JB, Borleffs CJ, Cannegieter SC, Bax JJ, van Erven L; et al. (2011). "Long-term follow-up of primary and secondary prevention implantable cardioverter defibrillator patients". Europace. 13 (3): 389–94. doi:10.1093/europace/euq494. PMID 21208947.
- ↑ Kuck KH, Schaumann A, Eckardt L, Willems S, Ventura R, Delacrétaz E; et al. (2010). "Catheter ablation of stable ventricular tachycardia before defibrillator implantation in patients with coronary heart disease (VTACH): a multicentre randomised controlled trial". Lancet. 375 (9708): 31–40. doi:10.1016/S0140-6736(09)61755-4. PMID 20109864.
- ↑ Schleberger R, Jularic M, Salzbrunn T, Hacke C, Schwarzl JM, Hoffmann BA; et al. (2020). "Outcome of catheter ablation of non-reentrant ventricular arrhythmias in patients with and without structural heart disease". Eur J Med Res. 25 (1): 4. doi:10.1186/s40001-020-0400-y. PMC 7076989 Check
|pmc=value (help). PMID 32183887 Check|pmid=value (help). - ↑ Higgins JP, Andino A (2013). "Soccer and Sudden Cardiac Death in Young Competitive Athletes: A Review". J Sports Med (Hindawi Publ Corp). 2013: 967183. doi:10.1155/2013/967183. PMC 4590894. PMID 26464886.
- ↑ Lotfi A, Klein LW, Hira RS, Mallidi J, Mehran R, Messenger JC; et al. (2020). "SCAI expert consensus statement on out of hospital cardiac arrest". Catheter Cardiovasc Interv. 96 (4): 844–861. doi:10.1002/ccd.28990. PMID 32406999 Check
|pmid=value (help).