Dysautonomia: Difference between revisions
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{{Infobox_Disease | | {{Infobox_Disease | | ||
Name = {{PAGENAME}} | | Name = {{PAGENAME}} | | ||
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MeshID = D001342 | | MeshID = D001342 | | ||
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==Overview== | ==Overview== | ||
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The effects of dysautonomia may be minor, only limiting the patient's activities slightly, or they may be totally disabling, leaving the patient bedridden. | The effects of dysautonomia may be minor, only limiting the patient's activities slightly, or they may be totally disabling, leaving the patient bedridden. | ||
== | ==Historical Perspective== | ||
In the nineteenth and earlier twentieth centuries, a diagnosis that was almost solely given to women was called "[[neurasthenia]]," or a "weak nervous system." These women would present symptoms of fatigue, weakness, dizziness and fainting, and the doctor's orders would simply be bed rest. Some of these women died, while many others recovered. No one understood where the problems came from. | In the nineteenth and earlier twentieth centuries, a diagnosis that was almost solely given to women was called "[[neurasthenia]]," or a "weak nervous system." These women would present symptoms of fatigue, weakness, dizziness and fainting, and the doctor's orders would simply be bed rest. Some of these women died, while many others recovered. No one understood where the problems came from. | ||
Nowadays, diagnostic criteria and treatment for various forms of dysautonomia have sharpened, and doctors have realized that some men have it, too. | Nowadays, diagnostic criteria and treatment for various forms of dysautonomia have sharpened, and doctors have realized that some men have it, too. | ||
==Classification== | |||
==Pathophysiology== | |||
==Causes== | ==Causes== | ||
Causes of dysautonomias include [[Virus|viral]] [[illness]], genetic factors, exposure to chemicals, [[pregnancy]], [[autoimmune disorders]], and a [[Physical trauma|trauma]] or injury which damages the autonomic [[nervous system]]. | Causes of dysautonomias include [[Virus|viral]] [[illness]], genetic factors, exposure to chemicals, [[pregnancy]], [[autoimmune disorders]], and a [[Physical trauma|trauma]] or injury which damages the autonomic [[nervous system]]. | ||
== | ==Differentiating {{PAGENAME}} from Other Diseases== | ||
==Epidemiology and Demographics== | |||
==Risk Factors== | |||
==Screening== | |||
==Prognosis== | ==Natural History, Complications, and Prognosis== | ||
The outlook for patients with dysautonomia depends on the particular diagnostic category. Patients with chronic, progressive, generalized dysautonomia in the setting of central nervous system degeneration have a generally poor long-term prognosis. Death can occur in young children and the elderly. Younger patients can die from pneumonia, acute respiratory failure, or sudden cardiopulmonary arrest. | The outlook for patients with dysautonomia depends on the particular diagnostic category. Patients with chronic, progressive, generalized dysautonomia in the setting of central nervous system degeneration have a generally poor long-term prognosis. Death can occur in young children and the elderly. Younger patients can die from pneumonia, acute respiratory failure, or sudden cardiopulmonary arrest. | ||
There is some evidence that dysautonomia may be a factor in SIDS ([[sudden infant death syndrome]]). | There is some evidence that dysautonomia may be a factor in SIDS ([[sudden infant death syndrome]]). | ||
== | ==Diagnosis== | ||
===Diagnostic Criteria=== | |||
===History and Symptoms=== | |||
===Physical Examination=== | |||
===Laboratory Findings=== | |||
===Imaging Findings=== | |||
===Other Diagnostic Studies=== | |||
==Treatment== | |||
There is no cure for dysautonomia. There are medications to assist in stabilization, but are often needed on a long-term basis. Secondary forms may improve with treatment of the underlying disease. In many cases treatment of primary dysautonomia is symptomatic and supportive. Measures to combat orthostatic intolerance include elevation of the head of the bed, frequent small meals, a high-salt diet, fluid intake, and compression hose. Drugs such as fludrocortisone, midodrine, ephedrine, and SSRIs can also be used to treat symptoms. Treating dysautonomia can be difficult. Treatment that helps one individual may actually worsen the symptoms of another. Often drugs and measures that are helpful are found through trial and error. | |||
===Medical Therapy=== | |||
===Surgery=== | |||
===Prevention=== | |||
==See also== | ==See also== | ||
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==External links== | ==External links== | ||
* [http://www.dinet.org Dysautonomia Information Network] | * [http://www.dinet.org Dysautonomia Information Network] | ||
* [http://www.12morepages.com/ 12 More Pages-Learn to Live & Cope With Dysautonomia] | |||
* [http://www.dynakids.org Dysautonomia Youth Network of America, Inc. (DYNA)] | * [http://www.dynakids.org Dysautonomia Youth Network of America, Inc. (DYNA)] | ||
* [http://www.adiwebsite.org American Dysautonomia Institute] | * [http://www.adiwebsite.org American Dysautonomia Institute] | ||
* {{NINDS|dysautonomia}} | * {{NINDS|dysautonomia}} | ||
* [http://www.supportdysautonomia.org Dysautonomia Support Network (aka POTS Support Network)] | * [http://www.supportdysautonomia.org Dysautonomia Support Network (aka POTS Support Network)] | ||
==Sources== | |||
* [http://www.dynakids.org Dysautonomia Youth Network of America, Inc.] | |||
* [http://www.adiwebsite.org American Dysautonomia Institute] | |||
* [http://www.ndrf.org National Dysautonomia Research Foundation (NDRF)] | |||
* [http://www.dinet.org Dysautonomia Information Network] | |||
* [http://heartdisease.about.com/cs/womensissues/a/dysautonomia.htm A family of misunderstood disorders, by Richard N Fogoros] | |||
* [http://www.supportdysautonomia.org Dysautonomia Support Network (aka POTS Support Network)] | |||
* [http://www.12morepages.com/ 12 More Pages-Learn to Live & Cope With Dysautonomia] | |||
==References== | |||
{{reflist|2}} | |||
[[Category:Neurological disorders]] | [[Category:Neurological disorders]] | ||
[[ja:自律神経失調症]] | [[ja:自律神経失調症]] | ||
{{WikiDoc Help Menu}} | {{WikiDoc Help Menu}} | ||
{{WikiDoc Sources}} | {{WikiDoc Sources}} | ||
Latest revision as of 17:46, 2 August 2016
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WikiDoc Resources for Dysautonomia |
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Articles |
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Most recent articles on Dysautonomia Most cited articles on Dysautonomia |
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Media |
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Powerpoint slides on Dysautonomia |
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Evidence Based Medicine |
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Clinical Trials |
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Ongoing Trials on Dysautonomia at Clinical Trials.gov Clinical Trials on Dysautonomia at Google
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Guidelines / Policies / Govt |
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US National Guidelines Clearinghouse on Dysautonomia
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Books |
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News |
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Commentary |
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Definitions |
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Patient Resources / Community |
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Patient resources on Dysautonomia Discussion groups on Dysautonomia Patient Handouts on Dysautonomia Directions to Hospitals Treating Dysautonomia Risk calculators and risk factors for Dysautonomia
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Healthcare Provider Resources |
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Causes & Risk Factors for Dysautonomia |
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Continuing Medical Education (CME) |
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International |
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Business |
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Experimental / Informatics |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
| Dysautonomia | |
| ICD-10 | G90 |
|---|---|
| MeSH | D001342 |
Overview
Dysautonomia is any disease or malfunction of the autonomic nervous system. This includes postural orthostatic tachycardia syndrome (POTS), neurocardiogenic syncope, mitral valve prolapse dysautonomia, pure autonomic failure, multiple system atrophy (Shy-Drager syndrome), Autonomic Instability and a number of lesser-known disorders.
In some cases, dysautonomia results in a reduction in the ability of the heart and circulatory system to compensate for changes in posture, causing dizziness or syncope (fainting) when one, e.g., stands suddenly. In other cases, the heart may race (tachycardia) for no apparent reason (known as Inappropriate sinus tachycardia), or the kidneys may fail to properly retain water (diabetes insipidus).
The effects of dysautonomia may be minor, only limiting the patient's activities slightly, or they may be totally disabling, leaving the patient bedridden.
Historical Perspective
In the nineteenth and earlier twentieth centuries, a diagnosis that was almost solely given to women was called "neurasthenia," or a "weak nervous system." These women would present symptoms of fatigue, weakness, dizziness and fainting, and the doctor's orders would simply be bed rest. Some of these women died, while many others recovered. No one understood where the problems came from.
Nowadays, diagnostic criteria and treatment for various forms of dysautonomia have sharpened, and doctors have realized that some men have it, too.
Classification
Pathophysiology
Causes
Causes of dysautonomias include viral illness, genetic factors, exposure to chemicals, pregnancy, autoimmune disorders, and a trauma or injury which damages the autonomic nervous system.
Differentiating Dysautonomia from Other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications, and Prognosis
The outlook for patients with dysautonomia depends on the particular diagnostic category. Patients with chronic, progressive, generalized dysautonomia in the setting of central nervous system degeneration have a generally poor long-term prognosis. Death can occur in young children and the elderly. Younger patients can die from pneumonia, acute respiratory failure, or sudden cardiopulmonary arrest.
There is some evidence that dysautonomia may be a factor in SIDS (sudden infant death syndrome).
Diagnosis
Diagnostic Criteria
History and Symptoms
Physical Examination
Laboratory Findings
Imaging Findings
Other Diagnostic Studies
Treatment
There is no cure for dysautonomia. There are medications to assist in stabilization, but are often needed on a long-term basis. Secondary forms may improve with treatment of the underlying disease. In many cases treatment of primary dysautonomia is symptomatic and supportive. Measures to combat orthostatic intolerance include elevation of the head of the bed, frequent small meals, a high-salt diet, fluid intake, and compression hose. Drugs such as fludrocortisone, midodrine, ephedrine, and SSRIs can also be used to treat symptoms. Treating dysautonomia can be difficult. Treatment that helps one individual may actually worsen the symptoms of another. Often drugs and measures that are helpful are found through trial and error.
Medical Therapy
Surgery
Prevention
See also
External links
- Dysautonomia Information Network
- 12 More Pages-Learn to Live & Cope With Dysautonomia
- Dysautonomia Youth Network of America, Inc. (DYNA)
- American Dysautonomia Institute
- Template:NINDS
- Dysautonomia Support Network (aka POTS Support Network)
Sources
- Dysautonomia Youth Network of America, Inc.
- American Dysautonomia Institute
- National Dysautonomia Research Foundation (NDRF)
- Dysautonomia Information Network
- A family of misunderstood disorders, by Richard N Fogoros
- Dysautonomia Support Network (aka POTS Support Network)
- 12 More Pages-Learn to Live & Cope With Dysautonomia