Kikuchi disease: Difference between revisions

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	Kikuchi disease;
	Micrograph of a lymph node with Kikuchi disease showing the characteristic features (abundant histiocytes, necrosis without neutrophils) on H&E stain.

VisualWikitext

Latest revision as of 18:07, 18 September 2017

For patient information, click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords: Histiocytic necrotizing lymphadenitis; Kikuchi-Fujimoto disease; Kikuchi necrotizing lymphadenitis; phagocytic necrotizing lymphadenitis; subacute necrotizing lymphadenitis; necrotizing lymphadenitis

Overview

Historical Perspective

Pathophysiology

Causes

Differentiating Kikuchi disease from other Diseases

Epidemiology and Demographics

Natural History, Complications and Prognosis

Diagnosis

Treatment

Medical Therapy | Surgery | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

Related Chapters

For other causes of lymph node enlargement, see lymphadenopathy.

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+__NOTOC__
+'''For patient information, click [[{{PAGENAME}} (patient information)|here]]'''
 {{Infobox_Disease |
-   Name           = {{PAGENAME}} |
+   Name           = Kikuchi disease|
-   Image          = |
+   Image          = Kikuchi disease.jpg|
-   Caption        = |
+   Caption        = [[Micrograph]] of a [[lymph node]] with Kikuchi disease showing the characteristic features (abundant [[histiocytes]], [[necrosis]] without [[neutrophil]]s) on [[H&E stain]].|
-  DiseasesDB     = |
-  ICD10          = |
-  ICD9           = |
-  ICDO           = |
-  OMIM           = |
-  MedlinePlus    = |
-  eMedicineSubj  = |
-  eMedicineTopic = |
-  MeshID         = |
 }}
-{{SI}}
+{{Kikuchi disease}}
+{{CMG}}
-{{Editor Help}}
+{{SK}} Histiocytic necrotizing lymphadenitis; Kikuchi-Fujimoto disease; Kikuchi necrotizing lymphadenitis; phagocytic necrotizing lymphadenitis; subacute necrotizing lymphadenitis; necrotizing lymphadenitis
-'''Kikuchi's disease''' ('''histiocytic necrotizing lymphadenitis''') is a rare, non-cancerous enlargement of the [[lymph node]]s: the diagnosis can be confirmed by lymph node biopsy. It was originally described in Japan by Dr M. Kikuchi in 1972.<ref>Kikuchi M. Lymphadenitis showing focal reticulum cell hyperplasia with nuclear debris and phagocytes. ''Acta Hematol Jpn'' 1972;35:379–80.<!--No PMID--></ref>
+==[[Kikuchi disease overview|Overview]]==
+==[[Kikuchi disease historical perspective|Historical Perspective]]==
+==[[Kikuchi disease pathophysiology|Pathophysiology]]==
-Kikuchi's disease is a self limiting illness which has very similar symptoms to Hodgkin's lymphoma.  This has led to misdiagnosis to some patients and also resulting in dangerous cancer treatment to those suffering from Kikuchi's disease.
+==[[Kikuchi disease causes|Causes]]==
-The symptoms of Kikuchi's are the following:
+==[[Kikuchi disease differential diagnosis|Differentiating Kikuchi disease from other Diseases]]==
-* [[Lymphadenopathy]]
+==[[Kikuchi disease epidemiology and demographics|Epidemiology and Demographics]]==
-* Drenching night sweats
-* Fever
-* Bone-joint pain
-* Loss of appetite
-* Unexplained weight loss
-* General weakness
-* Fatigue
-* Mental unfocus
-The cause for this disease has not been established, and there is also no cure.  Kikuchi's patients are able to treat some symptoms and wait weeks to months before the symptoms of Kikuchi's has been suppressed.  In most reported cases, it is common for the debilitating symptoms to last for half a year; however, the disease does return to some patients after time.
+==[[Kikuchi disease natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
-Kikuchi's disease has been reported to be associated with infections of [[Epstein-Barr virus]], [[human herpesvirus 6]], [[toxoplasmosis]], and [[Human T-lymphotropic virus]] 1.
+==Diagnosis==
+[[Kikuchi disease history and symptoms|History and Symptoms]] | [[Kikuchi disease physical examination|Physical Examination]] | [[Kikuchi disease laboratory findings|Laboratory Findings]] | [[Kikuchi disease chest x ray|Chest X Ray]] | [[Kikuchi disease CT|CT]] | [[Kikuchi disease MRI|MRI]] | [[Kikuchi disease ultrasound|Ultrasound]] | [[Kikuchi disease other diagnostic studies|Other Diagnostic Studies]]
-For other causes of lymph node enlargement see [[lymphadenopathy]].
+==Treatment==
+[[Kikuchi disease medical therapy|Medical Therapy]] | [[Kikuchi disease surgery|Surgery]] | [[Kikuchi disease cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Kikuchi disease future or investigational therapies|Future or Investigational Therapies]]
-==References==
+==Case Studies==
-<references/>
+[[Kikuchi disease case study one|Case #1]]
+==Related Chapters==
+*For other causes of lymph node enlargement, see [[lymphadenopathy]].
-{{Symptoms and signs}}
-{{SIB}}
-[[Category:Rare disease]]
+[[Category:Rare diseases]]
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 {{WikiDoc Sources}}


Kikuchi disease
Micrograph of a lymph node with Kikuchi disease showing the characteristic features (abundant histiocytes, necrosis without neutrophils) on H&E stain.