Macroglobulinemia: Difference between revisions
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==Overview== | |||
'''Macroglobulinemia''' is the presence of increased levels of [[macroglobulin]]s in the circulating [[blood]]. | '''Macroglobulinemia''' is the presence of increased levels of [[macroglobulin]]s in the circulating [[blood]]. | ||
A plasma cell [[dyscrasia]] resembling [[leukemia]] with cells of lymphocytic, plasmacytic, or intermediate morphology, which secrete an [[immunoglobulin M]] monoclonal component. There is diffuse infiltration of bone marrow and also, in many cases, of the spleen, liver, or lymph nodes. The circulating macroglobulin produces symptoms of hyperviscosity syndrome: weakness, fatigue, bleeding disorders, and visual disturbances. Peak incidence is in the sixth and seventh decades. (Dorland, 28th ed) | A plasma cell [[dyscrasia]] resembling [[leukemia]] with cells of lymphocytic, plasmacytic, or intermediate morphology, which secrete an [[immunoglobulin M]] monoclonal component. There is diffuse infiltration of bone marrow and also, in many cases, of the spleen, liver, or lymph nodes. The circulating macroglobulin produces symptoms of [[hyperviscosity syndrome]]: [[weakness]], [[fatigue]], bleeding disorders, and visual disturbances. Peak incidence is in the sixth and seventh decades. (Dorland, 28th ed) | ||
==See also== | ==See also== | ||
* [[Waldenström macroglobulinemia]] | * [[Waldenström macroglobulinemia]] | ||
[[Category: | [[Category:Blood tests]] | ||
[[Category:Hematology]] | [[Category:Hematology]] | ||
Latest revision as of 17:07, 9 August 2012
| Macroglobulinemia | |
| ICD-9 | 273.3 |
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| MeSH | D008258 |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Macroglobulinemia is the presence of increased levels of macroglobulins in the circulating blood. A plasma cell dyscrasia resembling leukemia with cells of lymphocytic, plasmacytic, or intermediate morphology, which secrete an immunoglobulin M monoclonal component. There is diffuse infiltration of bone marrow and also, in many cases, of the spleen, liver, or lymph nodes. The circulating macroglobulin produces symptoms of hyperviscosity syndrome: weakness, fatigue, bleeding disorders, and visual disturbances. Peak incidence is in the sixth and seventh decades. (Dorland, 28th ed)