Clopidogrel overdose: Difference between revisions

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m (Protected "Clopidogrel overdose" [edit=sysop:move=sysop])
 
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{{CMG}}
#REDIRECT [[Clopidogrel#Overdosage]]
 
 
 
'''Overdose following clopidogrel administration''' may lead to prolonged [[bleeding]] time and subsequent bleeding complications. A single oral dose of clopidogrel at 1500 or 2000 mg/kg was lethal to mice and to rats and at 3000 mg/kg to baboons. Symptoms of acute toxicity were vomiting (in baboons), prostration, difficult breathing, and gastrointestinal hemorrhage in all species.
 
'''Recommendations About Specific Treatment'''
 
Based on biological plausibility, [[platelet]] [[transfusion]] may be appropriate to reverse the pharmacological effects of Plavix if quick reversal is required.
 
 
 
 
{{FDA}}
 
 
 
 
 
[[Category:Drugs]]

Latest revision as of 02:22, 22 July 2014