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'''For patient information, click [[Extranodal NK-T-cell lymphoma (patient information)|here]]'''
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| ICDO          = {{ICDO|9719|3}}
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| MeshID        = D054391
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{{Extranodal NK-T-cell lymphoma}}


'''Extranodal NK-T-cell lymphoma''' is a type of [[lymphoma]].<ref name="pmid16380410">{{cite journal |author=Lee J, Suh C, Park YH, ''et al'' |title=Extranodal natural killer T-cell lymphoma, nasal-type: a prognostic model from a retrospective multicenter study |journal=J. Clin. Oncol. |volume=24 |issue=4 |pages=612–8 |year=2006 |month=February |pmid=16380410 |doi=10.1200/JCO.2005.04.1384 |url=http://www.jco.org/cgi/pmidlookup?view=long&pmid=16380410}}</ref><ref name="pmid15963893">{{cite journal |author=Lee J, Park YH, Kim WS, ''et al'' |title=Extranodal nasal type NK/T-cell lymphoma: elucidating clinical prognostic factors for risk-based stratification of therapy |journal=Eur. J. Cancer |volume=41 |issue=10 |pages=1402–8 |year=2005 |month=July |pmid=15963893 |doi=10.1016/j.ejca.2005.03.010 |url=http://linkinghub.elsevier.com/retrieve/pii/S0959-8049(05)00218-2}}</ref><ref name="pmid19041057">{{cite journal |author=Lee J, Au WY, Park MJ, ''et al'' |title=Autologous hematopoietic stem cell transplantation in extranodal natural killer/T cell lymphoma: a multinational, multicenter, matched controlled study |journal=Biol. Blood Marrow Transplant. |volume=14 |issue=12 |pages=1356–64 |year=2008 |month=December |pmid=19041057 |doi=10.1016/j.bbmt.2008.09.014 |url=http://linkinghub.elsevier.com/retrieve/pii/S1083-8791(08)00405-9}}</ref>
{{CMG}}; {{AE}} {{RG}}  


It is called "extranodal" to emphasize that the location is not in the [[lymph node]]. It is sometimes further qualified as "nasal type".
{{SK}} Angiocentric T cell lymphoma; Extranodal NK-T-cell lymphoma, nasal type; Extranodal NK-T-cell lymphoma, extra nasal type


It can be associated with [[Epstein Barr virus]].<ref name="pmid11727268">{{cite journal |author=Stadlmann S, Fend F, Moser P, Obrist P, Greil R, Dirnhofer S |title=Epstein-Barr virus-associated extranodal NK/T-cell lymphoma, nasal type of the hypopharynx, in a renal allograft recipient: case report and review of literature |journal=Hum. Pathol. |volume=32 |issue=11 |pages=1264–8 |year=2001 |month=November |pmid=11727268 |doi= |url=http://linkinghub.elsevier.com/retrieve/pii/S0046817701559572}}</ref><ref name="pmid19033930">{{cite journal |author=Ferenczi K, Summers P, Aubert P, ''et al'' |title=A case of CD30+ nasal natural killer/T-cell lymphoma |journal=Am J Dermatopathol |volume=30 |issue=6 |pages=567–71 |year=2008 |month=December |pmid=19033930 |doi=10.1097/DAD.0b013e318184bc3f |url=http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?an=00000372-200812000-00006}}</ref>


[[RNAi]] against [[EBNA1]] has been proposed as a possible treatment.<ref name="pmid18769118">{{cite journal |author=Ian MX, Lan SZ, Cheng ZF, Dan H, Qiong LH |title=Suppression of EBNA1 expression inhibits growth of EBV-positive NK/T cell lymphoma cells |journal=Cancer Biol. Ther. |volume=7 |issue=10 |pages=1602–6 |year=2008 |month=October |pmid=18769118 |doi= |url=http://www.landesbioscience.com/journals/cbt/abstract.php?id=6564}}</ref>
==[[Extranodal NK-T-cell lymphoma overview|Overview]]==


==References==
==[[Extranodal NK-T-cell lymphoma historical perspective|Historical Perspective]]==
{{reflist|2}}
==[[Extranodal NK-T-cell lymphoma classification|Classification]]==
==[[Extranodal NK-T-cell lymphoma pathophysiology|Pathophysiology]]==
==[[Extranodal NK-T-cell lymphoma causes|Causes]]==
==[[Extranodal NK-T-cell lymphoma differential diagnosis|Differentiating Extranodal NK-T-cell lymphoma from other Diseases]]==
==[[Extranodal NK-T-cell lymphoma epidemiology and demographics|Epidemiology and Demographics]]==
==[[Extranodal NK-T-cell lymphoma risk factors|Risk Factors]]==
==[[Extranodal NK-T-cell lymphoma screening|Screening]]==
==[[Extranodal NK-T-cell lymphoma natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
==Diagnosis==
[[Extranodal NK-T-cell lymphoma diagnostic study of choice|Diagnostic study of choice]] | [[Extranodal NK-T-cell lymphoma history and symptoms|History and Symptoms]] | [[Extranodal NK-T-cell lymphoma physical examination|Physical Examination]] | [[Extranodal NK-T-cell lymphoma laboratory findings|Laboratory Findings]] | [[Extranodal NK-T-cell lymphoma electrocardiogram|Electrocardiogram]] | [[Extranodal NK-T-cell lymphoma x ray|X-Ray Findings]] | [[Extranodal NK-T-cell lymphoma echocardiography and ultrasound|Echocardiography and Ultrasound]] | [[Extranodal NK-T-cell lymphoma CT scan|CT-Scan Findings]] | [[Extranodal NK-T-cell lymphoma MRI|MRI Findings]] | [[Extranodal NK-T-cell lymphoma other imaging findings|Other Imaging Findings]] | [[Extranodal NK-T-cell lymphoma other diagnostic studies|Other Diagnostic Studies]]


{{Lymphoid malignancy}}
{{SIB}}


==Treatment==
[[Extranodal NK-T-cell lymphoma medical therapy|Medical Therapy]] | [[Extranodal NK-T-cell lymphoma interventions|Interventions]] | [[Extranodal NK-T-cell lymphoma surgery|Surgery]] | [[Extranodal NK-T-cell lymphoma primary prevention|Primary Prevention]] | [[Extranodal NK-T-cell lymphoma secondary prevention|Secondary Prevention]] | [[Extranodal NK-T-cell lymphoma cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Extranodal NK-T-cell lymphoma future or investigational therapies|Future or Investigational Therapies]]
==Case Studies==


[[Extranodal NK-T-cell lymphoma case study one|Case #1]]


{{WH}}
 
{{WS}}
{{Hematological malignancy histology}}
[[Category:Disease]]
[[Category:Hematology|Extranodal NK-T-cell lymphoma]]
[[Category:Types of cancer|Extranodal NK-T-cell lymphoma]]
[[Category:Oncology]]
 
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Latest revision as of 12:57, 16 October 2019

For patient information, click here

Extranodal NK-T-cell lymphoma Microchapters

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Overview

Historical Perspective

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Natural History, Complications and Prognosis

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CT

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Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ramyar Ghandriz MD[2]

Synonyms and keywords: Angiocentric T cell lymphoma; Extranodal NK-T-cell lymphoma, nasal type; Extranodal NK-T-cell lymphoma, extra nasal type


Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Extranodal NK-T-cell lymphoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic study of choice | History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | X-Ray Findings | Echocardiography and Ultrasound | CT-Scan Findings | MRI Findings | Other Imaging Findings | Other Diagnostic Studies


Treatment

Medical Therapy | Interventions | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1



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