Multicystic dysplastic kidney: Difference between revisions

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{{Infobox Disease |
{{Infobox Disease |
   Name          = Multicystic dysplastic kidney |
   Name          = Multicystic dysplastic kidney |
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'''For patient information, click [[Multicystic dysplastic kidney (patient information)|here]]'''
{{Multicystic dysplastic kidney}}
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==[[Multicystic dysplastic kidney overview|Overview]]==


==Overview==
==[[Multicystic dysplastic kidney historical perspective|Historical Perspective]]==


'''Multicystic dysplastic kidney''' (MCDK) is a condition that results from the malformation of the [[kidney]] during fetal development.  The kidney consists of irregular cysts of varying sizes and has zero function. <ref>Maria-Gisela Mercado-Deane, James E. Beeson, and Susan D. John. [http://radiographics.rsnajnls.org/cgi/content/abstract/22/6/1429 US of Renal Insufficiency in Neonates.] RadioGraphics 2002 22: 1429-1438.</ref>
==[[Multicystic dysplastic kidney classification|Classification]]==


==Epidemiology==
==[[Multicystic dysplastic kidney pathophysiology|Pathophysiology]]==
In the United States, the [[incidence]] of MCDK is estimated to be 1 in every 2400 live births.<ref>http://www.childrensmemorial.org/depts/fetalhealth/Fetal_MCDK.asp 1</ref>


==Diagnosis==
==[[Multicystic dysplastic kidney causes|Causes]]==


MCDK is usually diagnosed by [[ultrasound]] examination before birth.
==[[Multicystic dysplastic kidney differential diagnosis|Differentiating Multicystic dysplastic kidney from other Diseases]]==


==Diagnostic Findings==
==[[Multicystic dysplastic kidney epidemiology and demographics|Epidemiology and Demographics]]==


===Ultrasonography===
==[[Multicystic dysplastic kidney risk factors|Risk Factors]]==


* Mass of non-communicating cysts of variable size.
==[[Multicystic dysplastic kidney natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
* Unlike severe hydronephrosis, in which the largest cystic structure (the renal pelvis) lies in a central location and is surrounded by dilated calices, in multicystic dysplastic kidney the cyst distribution shows no recognizable pattern.
* Dysplastic, echogenic parenchyma may be visible between the cysts, but no normal renal parenchyma is seen.
 
[http://www.radswiki.net Images courtesy of RadsWiki]
 
<gallery>
Image:Multicystic dysplastic kidney 001.jpg|Ultrasonography: Multicystic dysplastic kidney
Image:Multicystic dysplastic kidney 002.jpg|Ultrasonography: Multicystic dysplastic kidney
</gallery>


 
==Diagnosis==
<gallery>
[[Multicystic dysplastic kidney history and symptoms|History and Symptoms]] | [[Multicystic dysplastic kidney physical examination|Physical Examination]] | [[Multicystic dysplastic kidney laboratory findings|Laboratory Findings]] | [[Multicystic dysplastic kidney voiding cystourethrography|Voiding Cystourethrography (VCUG)]] | [[Multicystic dysplastic kidney dimercaptosuccinic acid renal scanning|Dimercaptosuccinic Acid (DMSA) Renal Scanning ]] | [[Multicystic dysplastic kidney CT|CT]] | [[Multicystic dysplastic kidney ultrasound|Ultrasound]] | [[Multicystic dysplastic kidney other imaging findings|Other Imaging Findings]] | [[Multicystic dysplastic kidney other diagnostic studies|Other Diagnostic Studies]]
Image:Multicystic dysplastic kidney 003.jpg|Ultrasonography: Multicystic dysplastic kidney
Image:Multicystic dysplastic kidney 004.jpg|Ultrasonography: Multicystic dysplastic kidney
</gallery>


==Treatment==
==Treatment==
MCDK is not treatable. However, the patient is observed periodically for the first few years during which ultrasounds are generally taken to ensure the healthy kidney is functioning properly and that the unhealthy kidney is not causing adverse effects.
[[Multicystic dysplastic kidney medical therapy|Medical Therapy]] | [[Multicystic dysplastic kidney surgery|Surgery]] | [[Multicystic dysplastic kidney primary prevention|Primary Prevention]] | [[Multicystic dysplastic kidney secondary prevention|Secondary Prevention]] | [[Multicystic dysplastic kidney cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Multicystic dysplastic kidney future or investigational therapies|Future or Investigational Therapies]]


==External links==
==Case Studies==


*[http://goldminer.arrs.org/search.php?query=Multicystic%20dysplastic%20kidney Goldminer: Multicystic dysplastic kidney]
[[Multicystic dysplastic kidney case study one|Case #1]]
* http://www.childrensmemorial.org/depts/fetalhealth/Fetal_MCDK.asp
* {{Chorus|00279}}
 
==References==
{{reflist}}




{{Congenital malformations of urinary system}}
{{Congenital malformations of urinary system}}
{{SIB}}
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[[Category:Needs content]]
[[Category:Disease]]
[[Category:Congenital disorders]]
[[Category:Congenital disorders]]
[[Category:Kidney diseases]]
[[Category:Kidney diseases]]
 
[[Category:Urology]]
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Latest revision as of 19:37, 28 December 2012

Multicystic dysplastic kidney
Ultrasonography: Multicystic dysplastic kidney
Image courtesy of RadsWiki
ICD-10 Q61.4 (EUROCAT Q61.40-Q61.41)

For patient information, click here

Multicystic dysplastic kidney Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Multicystic dysplastic kidney from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Voiding Cystourethrography (VCUG)

Dimercaptosuccinic Acid (DMSA) Renal Scanning

CT

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

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Future or Investigational Therapies

Case Studies

Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Multicystic dysplastic kidney from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Voiding Cystourethrography (VCUG) | Dimercaptosuccinic Acid (DMSA) Renal Scanning | CT | Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1


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