Arthralgia: Difference between revisions
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{{SI}} | {{SI}} | ||
{{CMG}} | {{CMG}}; {{AE}}[[User:DrMars|Mohammadmain Rezazadehsaatlou[2]]]. | ||
{{ | ==Overview== | ||
'''Arthralgia''' (from Greek ''arthro-'', joint + ''-algos'', pain) literally means joint pain; <ref name="medterms_arthralgia"> | |||
{{cite web |url=http://www.medterms.com/script/main/art.asp?articlekey=2343|title= Arthralgia Definition|accessdate=2007-09-20|format= HTML|work=MedicineNet.com }}</ref><ref name="jgh_arthralgia"> {{cite web|url=http://www.ncbi.nlm.nih.gov/books/bv.fcgi?indexed=google&rid=cm.chapter.4738|title= Arthralgia|author=Joe G. Hardin|accessdate=2007-09-20|format= HTML|work=Clinical Methods - The History, Physical, and Laboratory Examinations }}</ref> it is a symptom of injury, [[infection]], illnesses in particular [[arthritis]] or an [[allergic reaction]] to medication.<ref name="drugReaction" > {{cite web |url=http://www.ncbi.nlm.nih.gov/books/bv.fcgi?highlight=arthralgia&rid=cm.chapter.5910#5949 | |||
|title= Allergic Drug Reactions - Systemic Allergic Drug Reactions|author=James R Philp|accessdate=2007-09-20|format= HTML|work=Clinical Methods - The History, Physical, and Laboratory Examinations }}</ref> | |||
According to [[MeSH]], the term arthralgia should only be used when the condition is non-inflammatory, and the term arthritis should be used when the condition is inflammatory.<ref name="title">{{cite web|url=http://www.nlm.nih.gov/cgi/mesh/2008/MB_cgi?field=uid&term=D018771 |title=MeSH |accessdate=2007-12-23 |format= |work=}}</ref> | |||
==Causes== | |||
The causes of arthralgia are varied and range from, a joints perspective, degenerative and destructive processes such as [[Arthritic|osteoarthritis]] and sports injuries to inflammation of tissues surrounding the joints (e.g. [[bursitis]], a painful inflammation of bursa, fluid filled sacks around the joints). <ref name="nihbook_2">{{cite web |url=http://www.ncbi.nlm.nih.gov/books/bv.fcgi?indexed=google&rid=cm.chapter.4738 | |||
The causes of | |||
|title= Table 161.1. Some Common Regional Rheumatic Syndromes | |title= Table 161.1. Some Common Regional Rheumatic Syndromes | ||
|author=Joe G. Hardin | |author=Joe G. Hardin | ||
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|work=Clinical Methods - The History, Physical, and Laboratory Examinations }}</ref> | |work=Clinical Methods - The History, Physical, and Laboratory Examinations }}</ref> | ||
== | ===Common Causes=== | ||
* [[Behcet's disease]] | |||
* [[Chikungunya virus]] | |||
* [[ | |||
* [[Chikungunya | |||
* [[Crohn's disease]] | * [[Crohn's disease]] | ||
* [[ | * [[Dengue fever]] | ||
* [[ | * [[Gout]] | ||
* [[ | * [[Osteoarthritis]] | ||
* [[ | * [[Rheumatoid arthritis]] | ||
* [[ | * [[Rheumatic fever]] | ||
* [[ | * [[Ross river virus]] | ||
* [[Lupus erythematosus]] | * [[Lupus erythematosus]] | ||
* [[ | * [[Tenosynovitis]] | ||
* [[ | * [[Ulcerative colitis]] | ||
* Medication like [[terconazole]] | |||
* [[ | |||
=== | ===Causes by Organ System=== | ||
{|style="width:80%; height:100px" border="1" | {|style="width:80%; height:100px" border="1" | ||
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular''' | |style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular''' | ||
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | | |style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | [[Dressler's syndrome]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Dermatologic''' | | '''Dermatologic''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"|[[Blau syndrome]], [[Ehlers-Danlos syndrome]], [[Erythema elevatum diutinum]], [[Lepromatous leprosy]], [[Lipoid dermatoarthritis]], [[Lupus erythematosus]], [[Lyme disease]], [[Mixed connective tissue disease]], [[scleroderma]], PAPA syndrome, [[Pyoderma gangrenosum]], [[Rheumatic Fever]], [[Scleroderma]],[[syphilis]], [[Sweet's disease]], [[Systemic sclerosis]], [[Erythema nodosum]], [[Psoriasis]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Drug Side Effect''' | | '''Drug Side Effect''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| [[Acitretin]], [[Artemether/lumefantrine]], [[Asenapine maleate]], [[hyaluronic acid]], [[Bismuth]], [[Carbimazole]], [[Carfilzomib]], [[Cefadroxil]], [[Cidofovir]], [[Clomifene]], [[Ciprofloxacin]], [[caspofungin acetate]], [[Cefaclor]], [[Cyanocobalamin]], [[Deferiprone]], [[Efavirenz]], [[Enzalutamide]],[[Eliglustat]], [[eribulin]], [[Ethambutol]], [[Exemestane]], [[Fluorosis]], [[galsulfase]], [[Goserelin]], [[Gemifloxacin mesylate]], [[Idursulfase]], [[Indinavir]], [[Interferon gamma]], [[Isotretinoin]], [[Ivacaftor]], [[Ixabepilone]], [[Letrozole]], [[Methimazole]],[[Mianserin]], [[Mifepristone]], [[Minocycline hydrochloride]], [[mirtazapine]], [[Nabilone]], [[Natalizumab]], [[nefazodone]], [[Nalidixic acid]], [[Nateglinide]], [[Norfloxacin]], [[Omalizumab]], [[Paclitaxel]], [[Pantoprazole]], [[Pentamidine Isethionate]], [[Pergolide]], [[Pertuzumab]], [[Pirfenidone]], [[Plerixafor]], [[Propylthiouracil]], [[Pyrazinamide]], [[Potassium iodide]], [[Quinupristin dalfopristin]], [[Rasagiline]], [[Rifaximin]], [[Ropinirole]], [[Riluzole]], [[Romiplostim]], [[Sargramostim]], [[Sertraline]], [[Siltuximab]], [[Sorafenib]], [[Sulfasalazine]], [[Sunitinib]], [[Tiagabine]], [[Tenofovir]], [[Teriparatide]], [[Trastuzumab]], [[Valacyclovir]], [[Vilazodone]], [[Zanamivir]], [[Zotepine]], [[Zonisamide]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Endocrine''' | | '''Endocrine''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"|[[Acromegaly]], [[Obesity]], [[Avascular necrosis]], [[Secondary hyperparathyroidism]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Environmental''' | | '''Environmental''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"|[[Metal fume fever]], [[pneumoconiosis]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Gastroenterologic''' | | '''Gastroenterologic''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| [[Coeliac disease]], [[Crohn's disease]], [[Hepatitis]] A, B, C, [[Ulcerative Colitis]], [[Whipple disease]], [[Wilson's disease]], [[Autoimmune Hepatitis]], [[Celiac Sprue]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Genetic''' | | '''Genetic''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| [[Ankylosing spondylitis]], [[Celiac Sprue]], [[Gaucher's disease]], [[Hereditary multiple exostoses]], Legg-Calve-Perthes syndrome, [[Limb-girdle muscular dystrophy]], [[Marfan syndrome]], [[Noonan's Syndrome]], [[Recessive Multiple Epiphyseal Dysplasia]], [[Muscular dystrophy]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Hematologic''' | | '''Hematologic''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| [[Haemochromatosis]], [[Haemophilia type A]], [[Henoch-Schönlein purpura]], [[Acute myeloid leukemia]], [[Acute promyelocytic leukemia]], [[Leukemia]], [[Thrombotic thrombocytopenic purpura]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Iatrogenic''' | | '''Iatrogenic''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| *[[Arthrofibrosis]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Infectious Disease''' | | '''Infectious Disease''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| [[Atypical pneumonia]], [[Borrelia burgdorferi]], [[Lyme Disease]], [[Chikungunya virus]], [[Coccidioidomycosis]] lung infection, [[Community-acquired pneumonia]] | ||
[[Hepatitis]] A; B; C, [[Lepromatous leprosy]], [[Lyme disease]], [[Malaria]], Mayaro virus fever, [[Mycoplasma pneumoniae]], O'nyong-nyong fever, [[Parvovirus B19]] infection, [[Pharyngitis]], [[Rat bite fever]], [[Rheumatic Fever]], [[Ross River virus]], [[Rubella]], [[syphilis]], Semliki forest fever, [[Serum sickness]], [[Toxic shock syndrome]], [[Trichinosis]], [[West Nile fever]], [[Whipple disease]],[[Barmah Forest virus]], [[Chlamydia trachomatis]], [[Dengue fever]], [[Ebola]], [[Gonorrhea]], [[Relapsing fever]], [[Rocky Mountain spotted fever]], [[Tuberculosis]], [[Tularemia]], [[Yellow fever]], [[Yersinia enterocolitica Infection]], [[Yersinia pseudotuberculosis]], [[Zika fever]] | |||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Musculoskeletal / Ortho''' | | '''Musculoskeletal / Ortho''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| [[Blau syndrome]], [[Borrelia burgdorferi]], [[Fibromyalgia]], [[Gout]], congenital [[hip dysplasia]], [[Hypertrophic pulmonary osteoarthropathy]], Jacobs arthropathy-camptodactyly syndrome, [[Juvenile idiopathic arthritis]], Lipoid dermatoarthritis, [[Lupus erythematosus]], [[Lyme disease]], [[Mixed connective tissue disease]], | ||
Multiple epiphyseal dysplasia, [[Osteoarthritis]], [[Osteochondritis]] dissecans, [[Paget's disease of bone]], [[Palindromic rheumatism]], PAPA syndrome, [[Pigmented villonodular synovitis]], [[Polyarteritis nodosa]], [[Polychondritis]], Relapsing, Progressive pseudorheumatoid dysplasia, [[Pseudogout]], Recurrent hereditary [[polyserositis]], [[Rheumatoid arthritis]], [[Scleroderma]], Sclerosing [[osteomyelitis]] of Garre, [[Sjögren's syndrome]], [[Still's Disease]], [[Synovial chondromatosis]], [[Systemic sclerosis]], [[Takayasu's arteritis]], [[gout]],[[Adhesive capsulitis]] of shoulder, [[Ankylosing spondylitis]], [[Arthrofibrosis]], [[Avascular necrosis]], [[Baker's cyst]], [[Bursitis]],[[Erythema nodosum]], [[Marfan syndrome]], [[Osteoporosis]], [[Piriformis syndrome]], [[Plantar fasciitis]], [[Retropatellar Pain Syndrome]],[[Muscular dystrophy]], [[Scoliosis]], [[Slipped Upper Femoral Epiphysis]], [[Spondylitis]], [[Spondylolisthesis]], [[Spondylosis]],[[Subacromial bursitis]], [[Symphysis pubis dysfunction]], [[Tennis elbow]], [[Tenosynovitis]] | |||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Neurologic''' | | '''Neurologic''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| [[Neuropathic joint disease]], [[Poliomyelitis]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Nutritional / Metabolic''' | | '''Nutritional / Metabolic''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| [[Obesity]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Oncologic''' | | '''Oncologic''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| [[Acute lymphoblastic leukemia]], [[Multiple myeloma]], [[Pigmented villonodular synovitis]], [[Acute myeloid leukemia]], [[Acute promyelocytic leukemia]], [[Giant cell tumor of bone]], [[Hereditary multiple exostoses]], [[Hurler syndrome]], [[Leukemia]], [[Soft tissue sarcoma]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| ''' | | '''Ophthalmologic''' | ||
|bgcolor="Beige"| No underlying causes | |bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Pulmonary''' | | '''Pulmonary''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| [[Atypical pneumonia]], [[Caplan's disease]], [[Coccidioidomycosis]] lung infection, [[Community-acquired pneumonia]],[[Mycoplasma pneumoniae]], [[pneumoconiosis]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Renal / Electrolyte''' | | '''Renal / Electrolyte''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| [[Renal osteodystrophy]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Rheum / Immune / Allergy''' | | '''Rheum / Immune / Allergy''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"|[[Behcet's disease]], [[Caplan's disease]], [[Coeliac disease]], [[Crohn's disease]], [[Dressler's syndrome]], [[Erythema elevatum diutinum]], [[Hypothyroidism]], | ||
Juvenile chronic arthritis, [[Lupus erythematosus]], [[Mixed connective tissue disease]], [[Polyarteritis nodosa]], [[Polychondritis]], Relapsing [[Pyoderma gangrenosum]], [[Rheumatic Fever]], [[Rheumatoid arthritis]], [[Sarcoidosis]], [[Scleroderma]] , [[Serum sickness]],[[Sjögren's syndrome]], [[Still's Disease]], [[Systemic sclerosis]], [[Takayasu's arteritis]], [[Takayasu's arteritis]], [[Wegener's granulomatosis]], [[Ankylosing spondylitis]], [[Autoimmune Hepatitis]], [[Celiac Sprue]], [[Erythema nodosum]], [[Familial Mediterranean fever]], [[Iliotibial band syndrome]] | |||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Trauma''' | | '''Trauma''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| [[Bursitis]], [[Complex regional pain syndrome]], [[Diastasis symphysis pubis]], [[Golfer's elbow]], [[Slipped Upper Femoral Epiphysis]], [[Tennis elbow]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Miscellaneous''' | | '''Miscellaneous''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| [[Complex regional pain syndrome]], [[Familial Mediterranean fever]], [[Kikuchi disease]] | ||
|- | |- | ||
|} | |} | ||
===Causes in Alphabetical Order<ref>Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016</ref><ref>Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X</ref>=== | |||
{{MultiCol}} | |||
*[[Acitretin]] | |||
*[[Acute lymphoblastic leukemia]] | |||
*[[Acromegaly]] | |||
*[[Acute myeloid leukemia]] | |||
*[[Acute promyelocytic leukemia]] | |||
*[[Adhesive capsulitis]] of shoulder | |||
*Alkhurma virus | |||
*[[Ankylosing spondylitis]] | |||
*[[Arthrofibrosis]] | |||
*[[Artemether/lumefantrine]] | |||
*[[Atypical pneumonia]] | |||
*[[Autoimmune Hepatitis]] | |||
*[[Avascular necrosis]] | |||
*[[Baker's cyst]] | |||
*[[Barmah Forest virus]] | |||
*[[Behcet's disease]] | |||
*[[Bismuth]] | |||
*[[Blau syndrome]] (granulomatous [[arthritis]], [[iritis]], and [[skin rash]]) | |||
*[[Borrelia burgdorferi]] ([[Lyme Disease]]) | |||
*[[Bruton's agammaglobulinemia]] | |||
*[[Buprenorphine]]/[[Naloxone]] | |||
*[[Bursitis]] | |||
*[[Caplan's disease]] ([[rheumatoid arthritis]] and [[pneumoconiosis]]) | |||
*[[Carbimazole]] | |||
*[[Cefadroxil]] | |||
*[[Celiac Sprue]] | |||
*[[Chikungunya virus]] | |||
*[[Chlamydia trachomatis]] | |||
*[[Chronic fatigue syndrome]] | |||
*[[Cidofovir]] | |||
*[[Ciprofloxacin]] ([[Quinolone]]-induced cartilage toxicity in children) | |||
*[[Coccidioidomycosis]] lung infection | |||
*[[Coeliac disease]] | |||
*[[Community-acquired pneumonia]] | |||
*[[Complex regional pain syndrome]] | |||
*[[Crohn's disease]] | |||
*[[Cryoglobulinaemia]] | |||
*[[Cyanocobalamin]] | |||
*[[Decompression sickness]] | |||
*[[Deferiprone]] | |||
*[[Dengue fever]] | |||
*Diffuse idiopathic skeletal [[hyperostosis]] | |||
*[[Diastasis symphysis pubis]] | |||
*[[Dressler's syndrome]] | |||
*[[Ebola]] | |||
*[[Efavirenz]] | |||
*[[Ehlers-Danlos syndrome]] | |||
*[[Emtricitabine]] | |||
*[[Eribulin]] | |||
*[[Erythema nodosum]] | |||
*[[Erythema elevatum diutinum]] (is a rare type of [[leukocytoclastic vasculitis]] characterized by red, purple, brown, or yellow [[papule]]s, [[plaque]]s, or [[nodule]]s) | |||
*[[Exemestane]] | |||
*[[Familial Mediterranean fever]] | |||
*[[Farber's disease]] | |||
*[[Fibromyalgia]] | |||
*[[Fluorosis]] | |||
*[[Fracture]] of bone | |||
*[[Gamekeeper's thumb]] | |||
*[[Gaucher's disease]] | |||
*[[Giant cell tumor of bone]] | |||
*Gluten-sensitive enteropathy associated conditions | |||
*[[Golfer's elbow]] | |||
*[[Gonorrhea]] | |||
*[[Gout]] | |||
*[[Graft versus host disease]] | |||
*[[Haemochromatosis]] | |||
*[[Haemophilia type A]] | |||
*[[Henoch-Schönlein purpura]] | |||
*[[Hepatitis]] [[Hepatitis A|A]], [[Hepatitis B|B]], [[Hepatitis C|C]] | |||
*[[Hereditary multiple exostoses]] | |||
*[[Hip dysplasia]], congenital | |||
*[[HPV Vaccine]] ([[Gardasil]]) | |||
*[[Hurler syndrome]] | |||
*[[Hyperimmunoglobulinemia D]] and [[periodic fever syndrome]] ( attacks of [[fever]], arthralgia, [[skin lesion]]s, and [[diarrhea]]) | |||
*[[Hypertrophic pulmonary osteoarthropathy]] | |||
*[[Hypothyroidism]] | |||
*[[Iliotibial band syndrome]] | |||
*[[Indinavir]] | |||
*[[Infliximab]] | |||
*[[Interferon gamma]] | |||
*[[Interstitial nephritis]] | |||
*[[Ivacaftor]] | |||
*[[Isotretinoin]] | |||
*[[Ixabepilone]] | |||
*Jacobs arthropathy-camptodactyly syndrome | |||
*[[Janumet]] ([[sitagliptin]] and [[metformin]]) | |||
*[[Juvenile chronic arthritis]] | |||
*[[Kawasaki disease]] | |||
*[[Kikuchi disease]] | |||
*[[Kniest dysplasia]] | |||
*Legg-Calve-Perthes syndrome | |||
*[[Lepromatous leprosy]] | |||
*[[Leukemia]] | |||
*Ligamentous laxity | |||
*[[Limb-girdle muscular dystrophy]] | |||
*Lipoid dermatoarthritis | |||
*[[Lupus erythematosus]] | |||
*[[Lyme disease]] | |||
*[[Malaria]] | |||
*[[Marfan syndrome]] | |||
*Mayaro virus fever | |||
*[[Metal fume fever]] | |||
*[[Methimazole]] | |||
*[[Mianserin]] ([[antidepressant]], also [[mirtazapine]] and [[nefazodone]] are associated with arthralgia) | |||
*[[Mifepristone]] | |||
*[[Mixed connective tissue disease]] | |||
*[[Morphoea]]/[[scleroderma]] | |||
{{ColBreak}} | |||
*Multiple epiphyseal dysplasia: Recessive multiple epiphyseal dysplasia | |||
*[[Multiple myeloma]] | |||
*[[Muscular dystrophy]] | |||
*[[Mycoplasma pneumoniae]] | |||
*[[Nabilone]] | |||
*[[Nalidixic acid]] | |||
*[[Natalizumab]] | |||
*[[Nateglinide]] | |||
*[[Neuropathic joint disease]] | |||
*[[Noonan's Syndrome]] | |||
*[[Norfloxacin]] | |||
*[[Obesity]] | |||
*O'nyong-nyong fever | |||
*[[Osteoarthritis]] | |||
*[[Osteochondritis]] dissecans | |||
*[[Osteoporosis]] | |||
*Otospondylomegaepiphyseal dysplasia | |||
*[[Paclitaxel]] | |||
*[[Paget's disease of bone]] | |||
*[[Palindromic rheumatism]] (idiopathic, periodic arthritis marked by multiple and recurrent attacks affecting one to a few joints, with tissue inflammation around or adjacent to them) | |||
*[[Pantoprazole]] | |||
*PAPA syndrome ( Pyogenic arthritis, pyoderma gangrenosum and acne (PAPA) syndrome) | |||
*[[Parvovirus B19]] infection | |||
*[[Pergolide]] | |||
*[[Pharyngitis]] | |||
*[[Pigmented villonodular synovitis]] | |||
*[[Pituitary tumour]] (*[[Acromegaly]], growth hormone secreting tumor) | |||
*[[Pirfenidone]] | |||
*[[Piriformis syndrome]] | |||
*[[Plantar fasciitis]] | |||
*[[Plerixafor]] | |||
*[[pneumoconiosis]] | |||
*[[Poliomyelitis]] | |||
*[[Polyarteritis nodosa]] | |||
*[[Polychondritis]], Relapsing | |||
*Progressive pseudorheumatoid dysplasia | |||
*[[Propylthiouracil]] | |||
*[[Psoriasis]] | |||
*[[Pyoderma gangrenosum]] | |||
*[[Pyrazinamide]] | |||
*[[Pyrophosphate arthropathy]] ([[Pseudogout]]) | |||
*[[Rat bite fever]] (Streptobacillus moniliformis or Spirillum minus) | |||
*[[Reactive arthritis]] | |||
*Recessive multiple epiphyseal dysplasia | |||
*Recurrent hereditary polyserositis | |||
*[[Relapsing fever]] | |||
*[[Renal osteodystrophy]] | |||
*[[Retropatellar Pain Syndrome]] | |||
*[[Rheumatic Fever]] | |||
*[[Rheumatoid arthritis]] | |||
*[[Rocky Mountain spotted fever]] | |||
*[[Ross River virus]] | |||
*[[Rubella]] | |||
*[[Sarcoidosis]] | |||
*[[Scleroderma]] | |||
*[[Scoliosis]] | |||
*[[Secondary hyperparathyroidism]] | |||
*Sclerosing [[osteomyelitis]] of Garre | |||
*Secondary [[syphilis]] | |||
*Semliki forest fever | |||
*[[Serum sickness]] | |||
*[[Sickle cell disease]] | |||
*[[Siltuximab]] | |||
*[[Sjögren's syndrome]] | |||
*[[Slipped Upper Femoral Epiphysis]] | |||
*[[Soft tissue sarcoma]] | |||
*[[Sorafenib]] | |||
*[[Spondylitis]] | |||
*[[Spondylolisthesis]] | |||
*[[Spondylosis]] | |||
*[[Stickler syndrome]] | |||
*[[Still's Disease]], Juvenile-Onset | |||
*[[Subacromial bursitis]] | |||
*[[Sunitinib]] | |||
*[[Sweet's disease]] | |||
*[[Symphysis pubis dysfunction]] | |||
*[[Synovial chondromatosis]] | |||
*[[Systemic sclerosis]] | |||
*[[Takayasu's arteritis]] | |||
*[[Tennis elbow]] | |||
*[[Tenofovir]] disoproxil fumarate | |||
*[[Tenosynovitis]] | |||
*[[Teriparatide]] | |||
*[[Tiagabine]] | |||
*[[Thrombotic thrombocytopenic purpura]] | |||
*[[Toxic shock syndrome]] | |||
*[[Trastuzumab]] | |||
*[[Trichinosis]] | |||
*[[Tuberculosis]] | |||
*[[Tularemia]] | |||
*[[Ulcerative Colitis]] | |||
*Urate crystal arthropathy ([[gout]]) | |||
*[[Vilazodone]] | |||
*[[Waldenström macroglobulinemia]] | |||
*[[Wegener's granulomatosis]] | |||
*[[West Nile fever]] | |||
*[[Whipple disease]] | |||
*[[Wilson's disease]] | |||
*Wissler-Fanconi syndrome | |||
*[[Yellow fever]] | |||
*[[Yersinia enterocolitica Infection]] (Yersiniosis) | |||
*[[Yersinia pseudotuberculosis]] | |||
*[[Zanamivir]] | |||
*[[Zika fever]] | |||
*[[Zotepine]] | |||
{{EndMultiCol}} | |||
==Diagnosis== | |||
===History and Symptoms=== | |||
Diagnosis involves interviewing the patient and performing physical exams. When attempting to establish the cause of the arthralgia, the emphasis is on the interview.<ref name="jgh_arthralgia"/> The patient is asked questions intended to narrow the number of potential causes. Given the varied nature of these possible causes, the questions may strike the uninitiated as irrelevant. For example the patient may be asked about [[dry mouth]], [[light sensitivity]], [[rash]]es or a history of [[seizure]]s.<ref name="jgh_arthralgia"/> <ref name="spondyl_table1" > {{cite web |url=http://www.ncbi.nlm.nih.gov/books/bv.fcgi?highlight=arthralgia&rid=cm.chapter.5910#5949 | |||
|title= Table 159.3. Selected Symptomatic Extraarticular Features of the Connective Tissue Diseases and the Spondyloarthropathies | |||
|accessdate=2007-09-20 | |||
|format= HTML | |||
|work=Clinical Methods - The History, Physical, and Laboratory Examinations }}</ref> | |||
Answering yes or no to any of these questions limits the number of possible causes and guides the doctor toward the appropriate exams and lab tests. | |||
==Treatment== | |||
===Medical Therapy=== | |||
Treatment depends on specific underlying cause. The underlying cause will be treated first and foremost. The treatments may include [[immunosuppressant]]s for [[immune system]] dysfunction, [[antibiotic]]s when an [[infection]] is the cause, and discontinuing medication when an allergic reaction is the cause. When treating the primary cause, pain management may still play a role in treatment. The extent of its role varies depending on the specific cause of the arthralgia. Pain management may include stretching exercises, over the counter pain medications, prescription [[pain]] medication, or other treatments deemed appropriate for the symptoms. | |||
===Surgery=== | |||
Joint replacement surgery is done for severely damaged [[joint]]s. | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
{{Diseases of the musculoskeletal system and connective tissue}} | {{Diseases of the musculoskeletal system and connective tissue}} | ||
[[de:Arthralgie]] | [[de:Arthralgie]] | ||
[[fr:Arthralgie]] | [[fr:Arthralgie]] | ||
[[pl:Artralgia]] | |||
{{WH}} | |||
{{WS}} | |||
[[Category:Rheumatology]] | [[Category:Rheumatology]] | ||
[[Category:Symptoms]] | |||
[[Category:Signs and symptoms]] | [[Category:Signs and symptoms]] | ||
Latest revision as of 13:25, 6 August 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohammadmain Rezazadehsaatlou[2].
Overview
Arthralgia (from Greek arthro-, joint + -algos, pain) literally means joint pain; [1][2] it is a symptom of injury, infection, illnesses in particular arthritis or an allergic reaction to medication.[3] According to MeSH, the term arthralgia should only be used when the condition is non-inflammatory, and the term arthritis should be used when the condition is inflammatory.[4]
Causes
The causes of arthralgia are varied and range from, a joints perspective, degenerative and destructive processes such as osteoarthritis and sports injuries to inflammation of tissues surrounding the joints (e.g. bursitis, a painful inflammation of bursa, fluid filled sacks around the joints). [5]
Common Causes
- Behcet's disease
- Chikungunya virus
- Crohn's disease
- Dengue fever
- Gout
- Osteoarthritis
- Rheumatoid arthritis
- Rheumatic fever
- Ross river virus
- Lupus erythematosus
- Tenosynovitis
- Ulcerative colitis
- Medication like terconazole
Causes by Organ System
Causes in Alphabetical Order[6][7]
Diagnosis
History and Symptoms
Diagnosis involves interviewing the patient and performing physical exams. When attempting to establish the cause of the arthralgia, the emphasis is on the interview.[2] The patient is asked questions intended to narrow the number of potential causes. Given the varied nature of these possible causes, the questions may strike the uninitiated as irrelevant. For example the patient may be asked about dry mouth, light sensitivity, rashes or a history of seizures.[2] [8] Answering yes or no to any of these questions limits the number of possible causes and guides the doctor toward the appropriate exams and lab tests.
Treatment
Medical Therapy
Treatment depends on specific underlying cause. The underlying cause will be treated first and foremost. The treatments may include immunosuppressants for immune system dysfunction, antibiotics when an infection is the cause, and discontinuing medication when an allergic reaction is the cause. When treating the primary cause, pain management may still play a role in treatment. The extent of its role varies depending on the specific cause of the arthralgia. Pain management may include stretching exercises, over the counter pain medications, prescription pain medication, or other treatments deemed appropriate for the symptoms.
Surgery
Joint replacement surgery is done for severely damaged joints.
References
- ↑ "Arthralgia Definition" (HTML). MedicineNet.com. Retrieved 2007-09-20.
- ↑ 2.0 2.1 2.2 Joe G. Hardin. "Arthralgia" (HTML). Clinical Methods - The History, Physical, and Laboratory Examinations. Retrieved 2007-09-20.
- ↑ James R Philp. "Allergic Drug Reactions - Systemic Allergic Drug Reactions" (HTML). Clinical Methods - The History, Physical, and Laboratory Examinations. Retrieved 2007-09-20.
- ↑ "MeSH". Retrieved 2007-12-23.
- ↑ Joe G. Hardin. "Table 161.1. Some Common Regional Rheumatic Syndromes" (HTML). Clinical Methods - The History, Physical, and Laboratory Examinations. Retrieved 2007-09-20.
- ↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
- ↑ Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X
- ↑ "Table 159.3. Selected Symptomatic Extraarticular Features of the Connective Tissue Diseases and the Spondyloarthropathies" (HTML). Clinical Methods - The History, Physical, and Laboratory Examinations. Retrieved 2007-09-20.
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