Ajmaline: Difference between revisions
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{{drugbox | | {{drugbox | | ||
| IUPAC_name = | | IUPAC_name =(17''R'',21β)-ajmalan-17,21-diol<br />OR<br />(1''R'',9''R'',10''S'',13''R'',14''R'',16''S'',18''S'')-13-ethyl-8-methyl-8,15-diazahexacyclo[14.2.1.0<sup>1,9</sup>.0<sup>2,7</sup>.0<sup>10,15</sup>.0<sup>12,17</sup>]nonadeca-2(7),3,5-triene-14,18-diol | ||
| image = Ajmaline_svg.png | | image = Ajmaline_svg.png | ||
| CAS_number = 4360-12-7 | | CAS_number = 4360-12-7 | ||
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| routes_of_administration = | | routes_of_administration = | ||
}} | }} | ||
__NOTOC__ | |||
{{SI}} | {{SI}} | ||
{{CMG}} | {{CMG}} | ||
==Overview== | ==Overview== | ||
'''Ajmaline''' is a class Ia [[antiarrhythmic agent]]. It is often used to | '''Ajmaline''' is a class Ia [[antiarrhythmic agent]]. It is often used to bring out typical findings of ST elevations in patients suspected of having [[Brugada syndrome]]. | ||
The compound was first isolated by [[Salimuzzaman Siddiqui]] in 1931 <ref>Siddiqui, S. & Siddiqui, R.H. (1931). Journal of the Indian Chemical Society, vol. 8, pp. 667-680.</ref> from the roots of [[Rauwolfia serpentina]]. He named it [[Ajmaline]], after [[Hakim Ajmal Khan]], one of the most illustrious practitioners of [[Unani|Unani system of medicine]] in South Asia.<ref name="sandilvi">Ahmed Nasim Sandilvi (2003), [http://www.dawn.com/weekly/science/archive/030412/science5.htm Salimuzzaman Siddiqui: pioneer of scientific research in Pakistan]. Daily Dawn. 12 April, 2003. Retrieved on 19 July, 2007.</ref> | The compound was first isolated by [[Salimuzzaman Siddiqui]] in 1931 <ref>Siddiqui, S. & Siddiqui, R.H. (1931). Journal of the Indian Chemical Society, vol. 8, pp. 667-680.</ref> from the roots of [[Rauwolfia serpentina]]. He named it [[Ajmaline]], after [[Hakim Ajmal Khan]], one of the most illustrious practitioners of [[Unani|Unani system of medicine]] in South Asia.<ref name="sandilvi">Ahmed Nasim Sandilvi (2003), [http://www.dawn.com/weekly/science/archive/030412/science5.htm Salimuzzaman Siddiqui: pioneer of scientific research in Pakistan]. Daily Dawn. 12 April, 2003. Retrieved on 19 July, 2007.</ref> | ||
== | ==References== | ||
{{reflist}} | {{reflist|2}} | ||
{{Antiarrhythmic agents}} | {{Antiarrhythmic agents}} | ||
[[Category:Antiarrhythmic agents]] | [[Category:Antiarrhythmic agents]] | ||
[[Category:Drugs | [[Category:Cardiovascular Drugs]] | ||
[[Category:Drug]] | |||
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Latest revision as of 21:58, 23 July 2014
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| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C20H26N2O2 |
| Molar mass | 326.433 g/mol |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Ajmaline is a class Ia antiarrhythmic agent. It is often used to bring out typical findings of ST elevations in patients suspected of having Brugada syndrome.
The compound was first isolated by Salimuzzaman Siddiqui in 1931 [1] from the roots of Rauwolfia serpentina. He named it Ajmaline, after Hakim Ajmal Khan, one of the most illustrious practitioners of Unani system of medicine in South Asia.[2]
References
- ↑ Siddiqui, S. & Siddiqui, R.H. (1931). Journal of the Indian Chemical Society, vol. 8, pp. 667-680.
- ↑ Ahmed Nasim Sandilvi (2003), Salimuzzaman Siddiqui: pioneer of scientific research in Pakistan. Daily Dawn. 12 April, 2003. Retrieved on 19 July, 2007.
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