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| {{Infobox_Disease |
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| | '''For patient information, click [[Neuralgia (patient information)|here]] |
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| | {{Neuralgia}}{{SI}} |
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| | {{CMG}} '''Associate Editor-In-Chief:'''{{SM}} |
| DiseasesDB = |
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| ICD10 = {{ICD10|M|79|2|m|70}} |
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| ICD9 = {{ICD9|729.2}} |
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| eMedicineTopic = |
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| MeshID = D009437 |
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| {{Editor Help}} | | {{SK}} Nerve pain; painful neuropathy; neuropathic pain |
| | ==[[Neuralgia overview|Overview]]== |
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| ==Overview== | | ==[[Neuralgia historical perspective|Historical Perspective]]== |
| '''Neuralgia''' is a painful disorder of the [[nerves]]. Under the general heading of neuralgia are [[trigeminal neuralgia]] (TN), atypical facial pain, and [[postherpetic neuralgia]] (caused by [[shingles]] or herpes).
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| The affected nerves are responsible for sensing [[touch]], [[temperature|temperature sensation]] and [[pressure|pressure sensation]] in the [[face|facial]] area from the [[jaw]] to the [[forehead]]. The disorder generally causes short episodes of excruciating [[Pain and nociception|pain]], usually for less than two minutes and on only one side of the face. The pain can be described in a variety of ways such as "stabbing," "sharp," "like lightning," "burning," and even "itchy". In the atypical form of TN, the pain can also present as severe or merely aching and last for extended periods. The pain associated with TN is recognized as one of the most excruciating pains that can be experienced.
| | ==[[Neuralgia classification|Classification]]== |
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| Simple stimuli such as eating, talking, washing the face, or any light touch or [[sensation]] can trigger an attack (even the sensation of a gentle breeze). The attacks can occur in clusters or as an isolated attack. Some patients will have a [[muscle spasm]] which led to the original term for TN of "tic douloureux" ("tic", meaning '[[spasm]]', and "douloureux", meaning 'painful', in French).
| | ==[[Neuralgia pathophysiology|Pathophysiology]]== |
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| Neuralgia is a form of [[chronic pain]] and can be extremely difficult to diagnose. Patients usually show no physical abnormalities, and with the attacks generally lasting a very short time, it can be difficult to reach a doctor before the attack is over. Postherpetic neuralgia is the easiest to diagnose because it follows an obvious cause (shingles).
| | ==[[Neuralgia causes|Causes]]== |
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| Neuralgia is rare, especially in those under 30. Women are more likely to be affected than men, and those over 50 are at the greatest risk. In some cases, [[multiple sclerosis]] is related to nerve damage, causing the pain, so doctors will likely ask about family history to help diagnose. Nothing unusual can be seen in brain scans, so diagnosis is usually based on the description of the symptoms.
| | ==[[Neuralgia differential diagnosis|Differentiating Neuralgia from other Diseases]]== |
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| [[Medication]] for [[seizures]] has shown promise in managing neuralgia, and some people have found relief with surgery, though not always permanent relief. | | ==[[Neuralgia epidemiology and demographics|Epidemiology and Demographics]]== |
| | ==[[Neuralgia risk factors|Risk Factors]]== |
| | ==[[Neuralgia screening|Screening]]== |
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| | ==[[Neuralgia natural history, complications and prognosis|Natural History, Complications and Prognosis]]== |
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| ==Postherpetic neuralgia== | | ==Diagnosis== |
| | [[Neuralgia history and symptoms|History and Symptoms]] | [[Neuralgia physical examination|Physical Examination]] | [[Neuralgia laboratory findings|Laboratory Findings]] | [[Neuralgia CT|CT]] | [[Neuralgia MRI|MRI]] | [[Neuralgia other imaging findings|Other Imaging Findings]] | [[Neuralgia other diagnostic studies|Other Diagnostic Studies]] |
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| Not all of those diagnosed with shingles go on to experience postherpetic neuralgia, which can be more painful than shingles. The pain and sensitivity can last for months or even years. The pain is usually in the form of an intolerable sensitivity to any touch but especially light touch. Postherpetic neuralgia is not restricted to the face; it can occur anywhere on the body but usually occurs at the location of the shingles rash. [[clinical depression|Depression]] is not uncommon due to the pain and social isolation during the illness. Treatment for postherpetic neuralgia is the same as for other forms.
| | ==Treatment== |
| | [[Neuralgia medical therapy|Medical Therapy]] | [[Neuralgia surgery|Surgery]] | [[Neuralgia primary prevention|Primary Prevention]] | [[Neuralgia secondary prevention|Secondary Prevention]] | [[Neuralgia cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Neuralgia future or investigational therapies|Future or Investigational Therapies]] |
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| ==Atypical (trigeminal) neuralgia== | | ==Case Studies== |
| | [[Neuralgia case study one|Case #1]] |
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| {{Main|Trigeminal neuralgia}}
| | ==Related Chapters== |
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| The symptoms of atypical neuralgia (ATN) tend to be vague and misleading. This may be the most misdiagnosed form of neuralgia. The symptoms can be mistaken for [[migraines]], dental problems such as [[TMJ]], musculoskeletal issues, and [[hypochondriasis]]. This form of neuralgia is extremely rare, thus also contributing to the misdiagnosis. ATN can have a wide range of symptoms and the pain can fluctuate in intensity from mild aching to a crushing or burning sensation, and also to the extreme pain experienced with the more common trigeminal neuralgia.
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| The pain from ATN is usually less than that of trigeminal neuralgia, but is nearly continuous and periods of remission are rare. This form can also cause pain in the back of the scalp and neck.
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| Many attempts have been made to link ATN with psychological issues, though modern studies have shown no link. Theories have suggested that [[infections]] of the [[teeth]] or [[sinuses]], [[Blood vessel|vascular]] compression, [[physical trauma]], or past viral infections could be a cause. Evidence thus far seems to be anecdotal. Another interesting aspect is that this form affects men and women equally, unlike the trigeminal neuralgia, which is much more common in women than men.
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| ATN is also known as Atypical Facial Pain (ATP) or Persistent Idiopathic Facial Pain (PIFP).
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| ==Risks== | |
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| Neuralgia usually goes undiagnosed or misdiagnosed for extended periods, leading to a great deal of pain and frustration on the part of the patient. This disease has earned the nickname "the suicide disease," due to the unfortunate and drastic steps some have taken when they have been unable to find relief. Patients exhibiting symptoms need to be persistent, and willing to try different doctors to find the help they need.
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| [[Sleep deprivation]] and [[malnutrition]] have also been reported as byproducts of the pain. It is possible that there are other triggers or aggravating factors that patients need to learn to recognize to help manage their health. Bright lights, sounds, stress, and poor diet are examples of additional stimuli that can contribute to the condition. The pain can cause [[nausea]], so beyond the obvious need to treat the pain, it is important to be sure to try to get adequate rest and nutrition.
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| ==See also==
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| *[[Nerve]] | | *[[Nerve]] |
| *[[Neuropathy]] | | *[[Neuropathy]] |
| *[[Neuritis]] | | *[[Neuritis]] |
| *[[Cranial nerves]] | | *[[Cranial nerves]] |
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| ==External links==
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| * [http://www.umanitoba.ca/cranial_nerves/trigeminal_neuralgia/manuscript/types.html Good Pictures of the affected nerves]
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| * [http://www.tna-support.org/ Trigeminal Neuralgia Association]
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| * [http://www.emedicine.com/emerg/topic617.htm Medical Information]
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| * [http://www.aftershingles.com/phn.html Information on Post herpetic Neuralgia]
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| * [http://www.mayoclinic.com/invoke.cfm?id=DS00277 Mayo Clinic on Post herpetic Neuralgia]
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| * [http://www.mayoclinic.com/invoke.cfm?objectid=3454D91F-85AA-4775-8AACF811D6C5723A Mayo Clinic on Trigeminal Neuralgia]
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| * [http://facial-neuralgia.org/conditions/atfp.html Atypical Neuralgia]
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| * [http://www.emedicine.com/neuro/topic25.htm Medical Information on Atypical Neuralgia]
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| * [http://www.mytn.co.uk The Story of how one sufferers self diagnosis led to the Microvascular Decompression Operation]
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| * [http://www.nvchome.com Interesting website of Dr. Ramin Naraghi on neurovascular compression syndromes (NVC)]
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| == Literature ==
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| *Shankland, Dr. Wesley E. ''Face the Pain - The Challenge of Facial Pain'', (Omega Publishing, 2001) [http://www.drshankland.com/] Dr. Shankland is a former associate editor of ''The Journal of Craniomandibular Practice'' [http://www.cranio.com].
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| *Carol Jay Levy ''A Pained Life; A Chronic Pain Journey'', (Xlibris 2003) ISBN: 1-4134-0609-2. [https://www2.xlibris.com/bookstore/bookdisplay.asp?bookid=18435] Ms. Levy suffered from chronic pain for more than 2 decades. Her book tells the story of her pain and search for relief.
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| *R.C.Sherriffs 'Journeys End'; one of the lesser characters lies about suffering form Neuralgia in order to achieve a chance to go home.
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| [[Category:Neurology]] | | [[Category:Neurology]] |
| [[Category:Pain]] | | [[Category:Pain]] |
| [[Category:Neurological disorders]] | | [[Category:Neurological disorders]] |
| | [[Category:Overview complete]] |
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| [[de:Neuralgie]] | | [[de:Neuralgie]] |