Sudden cardiac versus non-cardiac death: Difference between revisions

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==Overview==
==Overview==
The term '''sudden cardiac death''' refers to [[natural death]] from cardiac causes, heralded by abrupt loss of [[consciousness]] within one hour of the onset of acute symptoms.<ref>Myerburg, Robert J. "Cardiac Arrest and Sudden Cardiac Death" in ''Heart Disease: A Textbook of Cardiovascular Medicine,'' 7th editionPhiladelphia: WB Saunders, 2005.</ref>  Other forms of sudden death may be noncardiac in origin and are therefore termed sudden death rather than sudden cardiac death. Examples of this include respiratory arrest (such as due to airway obstruction, which may be seen in cases of [[choking]] or [[asphyxiation]]), toxicity or poisoning, [[anaphylaxis]], or trauma.<ref>[http://poptop.hypermart.net/sudden.html Sudden Unexpected Death: Causes and Contributing Factors] on poptop.hypermart.net.</ref>
*[[Sudden cardiac death]] ([[SCD]]) is a natural, rapid, unexpected [[death]] secondary to [[cardiac]] causes within an hour of [[symptom onset]] in witnessed scenarios, and within a day in unwitnessed cases <ref name="pmid36844932">{{cite journal| author=Calvo Cuervo D| title=Comment on the ESC Guidelines 2022 for the Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death. | journal=Eur Cardiol | year= 2023 | volume= 18 | issue= | pages= e01 | pmid=36844932 | doi=10.15420/ecr.2022.48 | pmc=9947934 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=36844932  }} </ref>.
 
* [[Sudden cardiac arrest]] ([[SCA]]) is the unexpected cessation of pumping [[blood]] into vital [[organs]] due to electrical disturbance in the pathway of [[sinoatrial node]] ([[SA node]]), [[atrioventricular node]] ([[AV node]]), [[His Purkinje fibers]] or [[cardiac]] pumping failure due to [[cardiogenic shock]], massive [[pulmonary thromboembolism]],[[fulminant myocarditis]], and [[ruptured left ventricular free wall]].
It is important to make a distinction between this term and the related term '''[[cardiac arrest]]''', which refers to cessation of cardiac pump function which may be reversible (i.e., may not be fatal).  The phrase '''Sudden Cardiac Death''' is a [[public health]] concept incorporating the features of ''natural'', ''rapid'', and ''unexpected''.  It does not specifically refer to the mechanism or cause of death.  Although the most frequent underlying cause of Sudden Cardiac Death is [[Coronary Artery Disease]], other categories of causes are listed below.
*Without any intervention for immediate restoration of the [[circulation]], [[biologic death]] will happen minutes to weeks after [[cardiac arrest]]. [[Sudden cardiac death]] in the United States ranges from 300,000 to 400,000 which is 50% of all causes of deaths. <ref name="pmid21513133">{{cite journal| author=Haissaguerre M, Hocini M, Sacher F, Shah A| title=[Sudden cardiac death, a major scientific challenge]. | journal=Bull Acad Natl Med | year= 2010 | volume= 194 | issue= 6 | pages= 983-93; discussion 993-5 | pmid=21513133 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21513133  }} </ref> In-hospital [[cardiac arrest]] happens in 290,000 adults every year in the United States. The most common cause of [[sudden cardiac death]] is [[coronary artery disease]] and [[atherosclerosis]]. The presence of underlying disorders such as [[malignancy]] or [[liver disease]] at the time of [[ cardiac arrest]] makes the condition worse. Patients with [[acute myocardial infarction]] and [[in-hospital cardiac arrest]] with shockable [[rhythm]] have a better prognosis. Post [[cardiopulmonary resuscitation]] state management should be focused on [[neurologic]] [[complications]], [[hemodynamic]] stability, and [[respiratory]] support.
 
==Cardiac Arrest as a Subtype of Sudden Death==
A '''cardiac arrest''', also known as '''cardiorespiratory arrest''', '''cardiopulmonary arrest''' or '''circulatory arrest''', is the abrupt cessation of normal circulation of the [[blood]] due to failure of the [[heart]] to contract effectively during [[Systole (medicine)|systole]].<ref name="Harrison"> [http://books.mcgraw-hill.com/medical/harrisons/ Harrison's Principles of Internal Medicine] 16th Edition, The McGraw-Hill Companies, ISBN 0-07-140235-7</ref>
 
"Arrested" blood circulation prevents delivery of [[oxygen]] to ''all'' parts of the body. Cerebral [[hypoxia (medical)|hypoxia]], or lack of oxygen supply to the brain, causes victims to [[unconsciousness|lose consciousness]] and to [[respiratory arrest|stop normal breathing]]. Brain injury is likely if cardiac arrest is untreated for more than 5 minutes,<ref name="pmid3536160">{{cite journal |author=Safar P |title=Cerebral resuscitation after cardiac arrest: a review |journal=Circulation |volume=74 |issue=6 Pt 2 |pages=IV138–53 |year=1986 |month=December |pmid=3536160 |doi= |url=}}</ref> To improve survival and neurological recovery immediate response is paramount.<ref name="IrwinRippe"> [http://www.lww.com/product/?0-7817-3548-3 Irwin and Rippe's Intensive Care Medicine] by Irwin and Rippe, Fifth Edition (2003), Lippincott Williams & Wilkins, ISBN 0-7817-3548-3</ref>


Cardiac arrest is a [[medical emergency]] that, in certain groups of [[patient]]s, is potentially reversible if treated early enough (See Reversible Causes, below). When unexpected cardiac arrest leads to death this is called '''[[sudden cardiac death]]''' (SCD)<ref name="Harrison"> [http://books.mcgraw-hill.com/medical/harrisons/ Harrison's Principles of Internal Medicine] 16th Edition, The McGraw-Hill Companies, ISBN 0-07-140235-7</ref>. The primary first-aid treatment for cardiac arrest is ''[[cardiopulmonary resuscitation]]'' (commonly known as '''CPR''') to provide circulatory support until availability of definitive medical treatment, which will vary dependant on the rhythm the heart is exhibiting, but often requires [[defibrillation]].
==References==
{{reflist|2}}


[[Category:Cardiology]]
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Latest revision as of 19:09, 19 July 2023

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sara Zand, M.D.[2] Edzel Lorraine Co, DMD, MD[3]

Overview

References

  1. Calvo Cuervo D (2023). "Comment on the ESC Guidelines 2022 for the Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death". Eur Cardiol. 18: e01. doi:10.15420/ecr.2022.48. PMC 9947934 Check |pmc= value (help). PMID 36844932 Check |pmid= value (help).
  2. Haissaguerre M, Hocini M, Sacher F, Shah A (2010). "[Sudden cardiac death, a major scientific challenge]". Bull Acad Natl Med. 194 (6): 983–93, discussion 993-5. PMID 21513133.

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