Spinal muscular atrophy symptom: Difference between revisions
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'''Editors-in-Chief:''' [[C. Michael Gibson, M.S., M.D.]]; [[Priyamvada Singh]], [[MBBS]] | '''Editors-in-Chief:''' [[C. Michael Gibson, M.S., M.D.]]; [[Priyamvada Singh]], [[MBBS]] | ||
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* [http://www.jtsma.org.uk Jennifer Trust for Spinal Muscular Atrophy] - A national charity in the UK dedicated both to supporting people affected by SMA, and investing in essential research into causes, treatments and eventually a cure for the condition | * [http://www.jtsma.org.uk Jennifer Trust for Spinal Muscular Atrophy] - A national charity in the UK dedicated both to supporting people affected by SMA, and investing in essential research into causes, treatments and eventually a cure for the condition | ||
{{Diseases of the nervous system}} | {{Diseases of the nervous system}} | ||
Latest revision as of 16:13, 20 August 2012
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Spinal Muscular Atrophy Microchapters |
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Spinal muscular atrophy symptom Resources |
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Ongoing Trials on Spinal muscular atrophy symptom at Clinical Trials.gov |
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US National Guidelines Clearinghouse on Spinal muscular atrophy symptom |
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Directions to Hospitals Treating Spinal muscular atrophy symptom |
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Risk calculators and risk factors for Spinal muscular atrophy symptom |
Editors-in-Chief: C. Michael Gibson, M.S., M.D.; Priyamvada Singh, MBBS
Infantile SMA is the most severe form. Some of the symptoms include:
- muscle weakness
- poor muscle tone
- weak cry
- limpness or a tendency to flop
- difficulty sucking or swallowing
- accumulation of secretions in the lungs or throat
- legs that tend to be weaker than the arms
- hypotonia, areflexia, and multiple congenital contractures (arthrogryposis) associated with loss of anterior horn cells
- feeding difficulties
- increased susceptibility to respiratory tract infections
- developmental milestones, such as lifting the head or sitting up, can't be reached.
In general, the earlier the symptoms appear, the shorter the life span. The onset is sudden and dramatic. Once symptoms appear the motor neuron cells quickly deteriorate shortly after. The disease can be fatal and there is no cure for SMA yet known. The major management issue in Type 1 SMA is the prevention and early treatment of respiratory infections; pneumonia is the cause of death in the majority of the cases. Infants with Type 1 SMA have a life expectancy of less than two years, however, some grow to be adults. Intellectual and later, sexual functions, are unaffected by SMA.
References
External links
- Template:NINDS
- SMA Support
- Spinal Muscular Atrophy - Fight SMA - An international nonprofit dedicated to finding a treatment or cure for spinal muscular atrophy. Visit Fight SMA's website and also the Spinal Muscular Atrophy Blog for the latest news and research information about the leading genetic killer of children under two.
- Families of Spinal Muscular Atrophy - An international nonprofit dedicated to advancing research and supporting individuals and families with sma. FSMA has a web site with news, information and message boards for individuals to post questions. FSMA is one of the largest US private funders of SMA research and has more than 30 chapters worldwide.FSMA
- SMA Trust - a UK registered charity working to fund medical research into Spinal Muscular Atrophy
- Jennifer Trust for Spinal Muscular Atrophy - A national charity in the UK dedicated both to supporting people affected by SMA, and investing in essential research into causes, treatments and eventually a cure for the condition
Template:Diseases of the nervous system
da:Spinal muskulær atrofi de:Spinale Muskelatrophie el:Νωτιαία μυϊκή ατροφία nl:Spinale Musculaire Atrofieën fi:Spinaaliset lihasatrofiat sv:Spinal muskelatrofi