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{{DiseaseDisorder infobox |
__NOTOC__
  Name        = Mallory-Weiss syndrome |
{{Mallory-Weiss syndrome}}
  ICD10      = {{ICD10|K|22|6|k|20}} |
  ICD9        = {{ICD9|530.7}} |
}}
{{Search infobox}}


{{CMG}}
'''For patient information, click [[Mallory-Weiss syndrome (patient information)|here]]'''


{{Editor Join}}
{{CMG}}; {{AE}} {{DM}}


==Overview==
{{SK}} Mallory-Weiss tear; Mucosal lacerations
'''Mallory-Weiss syndrome''' refers to bleeding from tears (a ''Mallory-Weiss tear'') in the [[mucosa]] at the junction of the [[stomach]] and [[esophagus]], usually caused by severe retching, [[cough]]ing, or [[vomiting]]. It is often associated with [[alcoholism]] and [[eating disorders]] and there is some evidence that presence of a [[hiatus hernia|hiatal hernia]] is a required predisposing condition.


==Historical Perspective==
==[[Mallory-Weiss syndrome overview|Overview]]==
The condition was first described in 1929 by G. Kenneth Mallory and [[Soma Weiss]] in 15 alcoholic patients.
 
==[[Mallory-Weiss syndrome historical perspective|Historical Perspective]]==
 
==[[Mallory-Weiss syndrome classification|Classification]]==
 
==[[Mallory-Weiss syndrome pathophysiology|Pathophysiology]]==
 
==[[Mallory-Weiss syndrome causes|Causes]]==
 
==[[Mallory-Weiss syndrome differential diagnosis|Differentiating Mallory-Weiss syndrome from other Diseases]]==
 
==[[Mallory-Weiss syndrome epidemiology and demographics|Epidemiology and Demographics]]==
 
==[[Mallory-Weiss syndrome risk factors|Risk Factors]]==
 
==[[Mallory-Weiss syndrome screening|Screening]]==
 
==[[Mallory-Weiss syndrome natural history, complications and prognosis|Natural History, Complications, and Prognosis]]==


==Diagnosis==
==Diagnosis==
===Symptoms===
[[Mallory-Weiss syndrome history and symptoms|History and Symptoms]] | [[Mallory-Weiss syndrome physical examination|Physical Examination]] | [[Mallory-Weiss syndrome laboratory findings|Laboratory Findings]] | [[Mallory-Weiss syndrome electrocardiogram|Electrocardiogram]] | [[Mallory-Weiss syndrome x ray|X Ray]] | [[Mallory-Weiss syndrome CT|CT]] | [[Mallory-Weiss syndrome MRI|MRI]] | [[Mallory-Weiss syndrome other imaging findings|Other Imaging Findings]] | [[Mallory-Weiss syndrome other diagnostic studies|Other Diagnostic Studies]]
Mallory-Weiss syndrome often presents as an episode of vomiting up blood ([[hematemesis]]) after violent retching or vomiting, but may also be noticed as old blood in the stool ([[melena]]), and a history of retching may be absent. In most cases, the bleeding stops spontaneously after 24-48 hours, but endoscopic or surgical treatment is sometimes required and rarely the condition is fatal.


===Endoscopy===
==Treatment==
Definitive diagnosis is by [[Esophagogastroduodenoscopy|endoscopy]].
[[Mallory-Weiss syndrome medical therapy|Medical Therapy]] | [[Mallory-Weiss syndrome surgery|Surgery]] | [[Mallory-Weiss syndrome primary prevention|Primary Prevention]] | [[Mallory-Weiss syndrome secondary prevention|Secondary Prevention]] | [[Mallory-Weiss syndrome cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Mallory-Weiss syndrome future or investigational therapies|Future or Investigational Therapies]]


==Treatment==
==Case Studies==
Treatment is usually supportive as persistent bleeding is uncommon. However [[cauterization]] or injection of [[epinephrine]] to stop the bleeding may be undertaken during the index endoscopy procedure.  Very rarely [[embolization]] of the arteries supplying the region may be required to stop the bleeding. 
[[Mallory-Weiss syndrome case study one|Case #1]]


==Related Chapters==
==Related Chapters==
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*[[Hematemesis]]
*[[Hematemesis]]


==References==
* Weiss S, Mallory GK. ''Lesions of the cardiac orifice of the stomach produced by vomiting.'' [[Journal of the American Medical Association]] 1932;98:1353-55.
* [http://www.cecilmedicine.com/buy.cfm?book=goldman Cecil Textbook of Medicine]
* [http://www.emedicine.com/ped/topic1359.htm eMedicine] free password needed
* [http://www.oup.com/us/catalog/general/subject/Medicine/PrimaryCare/?ci=0192629220&view=usa The Oxford Textbook of Medicine]
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Latest revision as of 13:28, 8 December 2017

Mallory-Weiss syndrome Microchapters

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Overview

Historical Perspective

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Risk Factors

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Diagnosis

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X Ray

CT

MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Diab, MD [2]

Synonyms and keywords: Mallory-Weiss tear; Mucosal lacerations

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Mallory-Weiss syndrome from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications, and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | X Ray | CT | MRI | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

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