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==Overview==
==[[Hyperpituitarism overview|Overview]]==
'''Hyperpituitarism''' is the result of excess secretion of adenohypophyseal trophic [[hormones]] most commonly by a functional [[pituitary adenoma]]. Other causes are hyperplasias and carcinomas of the adenohypophysis, secretion by non-pituitary tumours and certain hypothalamic disorders.


==Clinical manifestations==
==[[Hyperpituitarism historical perspective|Historical Perspective]]==
Depending on the cell type(s) affected, clinical manifestations of hormone excess may include:
==[[Hyperpituitarism classification|Classification]]==
*[[Hyperprolactinaemia]]
==[[Hyperpituitarism pathophysiology|Pathophysiology]]==
*[[Cushing's disease]]
*[[Precocious puberty]]
*[[Gigantism]] or [[Acromegaly]]
*[[Hyperthyroidism]] (rare)


==Associated conditions==
==[[Hyperpituitarism causes|Causes]]==
When there is an enlargement of the pituitary tissue, hyperpituitarism is often associated with:
*[[Visual field]] defects, classically [[Bitemporal hemianopsia|bitemporal hemianopia]]
*Radiographic abnormalities of the [[sella turcica]], such as sellar expansion, bony erosion and disuption of the [[diaphragma sellae]]
*[[Intracranial pressure#Increased ICP|Increased intracranial pressure]]


==Symptoms==
==[[Hyperpituitarism differential diagnosis|Differentiating Hyperpituitarism from other Diseases]]==
Symptoms caused by hormone excess and associated mass effects include:
 
* [[Headache]]
==[[Hyperpituitarism epidemiology and demographics|Epidemiology and Demographics]]==
* Visual field loss or [[Double vision]]
 
* [[Excessive sweating]]
==[[Hyperpituitarism natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
* [[Hoarseness]]
 
* Milk secretion from [[breast]]
==Diagnosis==
* [[Sleep apnea]]
[[Hyperpituitarism history and symptoms|History and Symptoms]] | [[Hyperpituitarism physical examination|Physical Examination]] | [[Hyperpituitarism laboratory findings|Laboratory Findings]] | [[Hyperpituitarism CT|CT]] | [[Hyperpituitarism MRI|MRI]] | [[Hyperpituitarism ultrasound|Ultrasound]] | [[Hyperpituitarism other imaging findings|Other Imaging Findings]] | [[Hyperpituitarism other diagnostic studies|Other Diagnostic Studies]]
* [[Carpal tunnel syndrome]]
 
* [[Joint pain]] and limitation of motion
==Treatment==
* [[Muscle weakness]]
 
* [[Numbness]] or [[tingling of skin]]
[[Hyperpituitarism medical therapy|Medical Therapy]] | [[Hyperpituitarism surgery|Surgery]] | [[Hyperpituitarism primary prevention|Primary Prevention]] | [[Hyperpituitarism secondary prevention|Secondary Prevention]] | [[Hyperpituitarism cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Hyperpituitarism future or investigational therapies|Future or Investigational Therapies]]
 
==Case Studies==
[[Hyperpituitarism case study one|Case #1]]




{{Endocrine pathology}}
{{Endocrine pathology}}
{{SIB}}
 
[[Category:Endocrinology]]
[[Category:Endocrinology]]
[[Category:Mature chapter]]
 


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Latest revision as of 14:49, 20 September 2012

For patient information click here

Hyperpituitarism
ICD-10 E22
ICD-9 253.1
MeSH D006964

Hyperpituitarism Microchapters

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Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Hyperpituitarism from other Diseases

Epidemiology and Demographics

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Hyperpituitarism from other Diseases

Epidemiology and Demographics

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | CT | MRI | Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1



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