Metrorrhagia

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Metrorrhagia refers to vaginal bleeding among premenopausal women that is not synchronized with their menstrual period.

Etiology

• endometriosis
• ectopic pregnancy
• Use of progestin-only contraceptives, such as Depo Provera
• use of an IUD
• cervical cancer
• Uterine Leiomyomas

Drug Side Effect

• Estradiol valerate and estradiol valerate/dienogest
• Nitazoxanide
• Tiagabine

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