Herpes simplex primary prevention: Difference between revisions
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__NOTOC__ | |||
{{Herpes simplex}} | {{Herpes simplex}} | ||
{{CMG}} | {{CMG}}; {{AE}} {{CZ}} | ||
==Overview== | ==Overview== | ||
The [[National Institutes of Health]] (NIH) in the United States is currently in the midst of [[Clinical trial|phase III trials]] | The [[National Institutes of Health]] (NIH) in the United States is currently in the midst of [[Clinical trial|phase III trials]] for a [[vaccine]] against [[HSV-2]], called Herpevac.<ref name="titleHerpevac Trial for Women">{{cite web |url=http://www.niaid.nih.gov/dmid/stds/herpevac/ |title=Herpevac Trial for Women |accessdate=2008-02-25 |format= |work=}}</ref> The vaccine has only been shown to be effective for women who have never been exposed to [[HSV-1]]. Overall, the [[vaccine]] is approximately 48% effective in preventing [[HSV-2]] [[seropositivity]] and about 78% effective in preventing symptomatic [[HSV-2]].<ref name="titleHerpevac Trial for Women">{{cite web |url=http://www.niaid.nih.gov/dmid/stds/herpevac/studyover_faqs.htm |title=Herpevac Trial for Women |accessdate=2008-03-04 |format= |work=}}</ref> During initial trials, the vaccine did not exhibit any evidence of the prevention of [[HSV-2]] in males.<ref name="titleHerpevac Trial for Women"/> Additionally, the [[vaccine]] only reduced the acquisition of [[HSV-2]] and symptoms due to newly acquired [[HSV-2]] among women who did not have [[HSV-2]] infection at the time they got the [[vaccine]].<ref name="titleHerpevac Trial for Women"/> Because about 20% of people in the United States have [[HSV-2]] infection, this further reduces the population for whom this [[vaccine]] might be appropriate.<ref name="titleHerpevac Trial for Women"/> | ||
==Primary Prevention== | ==Primary Prevention== | ||
* The most effective way to avoid the transmission of [[sexually transmitted disease]]s, including [[genital herpes]], is to abstain from sexual contact, or to be in a long-term and mutually monogamous relationship with a partner who has been tested and is known to be uninfected. | |||
* [[Genital ulcer]] diseases can occur in both male and female genital areas that are covered or protected by a latex [[condom]], as well as in areas that are not covered. Correct and consistent use of latex condoms can reduce the risk of [[genital herpes]]. | |||
* People with [[Herpes simplex|herpes]] should abstain from sexual activity with uninfected partners when [[lesions]] or other symptoms of herpes are present. It is important to know that even if a person does not have any symptoms he or she can still infect sex partners. | |||
* Sex partners of infected persons should be advised that they may become infected and they should use condoms to reduce the risk of infection. | |||
* Sex partners can seek testing to determine if they are infected with [[HSV]]. A positive [[HSV-2]] [[blood test]] most likely indicates a [[genital herpes]] infection. | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
{{WH}} | |||
{{WS}} | |||
[[Category:Mature chapter]] | [[Category:Mature chapter]] | ||
[[Category:Sexually transmitted diseases]] | [[Category:Sexually transmitted diseases]] | ||
[[Category:Viral diseases]] | [[Category:Viral diseases]] | ||
[[Category:Gynecology]] | [[Category:Gynecology]] | ||
[[Category:Dermatology]] | [[Category:Dermatology]] | ||
[[Category:Obstetrics]] | [[Category:Obstetrics]] | ||
[[Category:Overview complete]] | [[Category:Overview complete]] | ||
[[Category:Disease | [[Category:Disease]] | ||
[[Category:Template complete]] | [[Category:Template complete]] | ||
[[Category:Emergency mdicine]] | |||
[[Category:Up-To-Date]] | |||
[[Category:Infectious disease]] | |||
[[Category:Otolaryngology]] | |||
[[Category:Urology]] | |||
Latest revision as of 22:09, 29 July 2020
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Herpes simplex primary prevention On the Web |
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Risk calculators and risk factors for Herpes simplex primary prevention |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]
Overview
The National Institutes of Health (NIH) in the United States is currently in the midst of phase III trials for a vaccine against HSV-2, called Herpevac.[1] The vaccine has only been shown to be effective for women who have never been exposed to HSV-1. Overall, the vaccine is approximately 48% effective in preventing HSV-2 seropositivity and about 78% effective in preventing symptomatic HSV-2.[1] During initial trials, the vaccine did not exhibit any evidence of the prevention of HSV-2 in males.[1] Additionally, the vaccine only reduced the acquisition of HSV-2 and symptoms due to newly acquired HSV-2 among women who did not have HSV-2 infection at the time they got the vaccine.[1] Because about 20% of people in the United States have HSV-2 infection, this further reduces the population for whom this vaccine might be appropriate.[1]
Primary Prevention
- The most effective way to avoid the transmission of sexually transmitted diseases, including genital herpes, is to abstain from sexual contact, or to be in a long-term and mutually monogamous relationship with a partner who has been tested and is known to be uninfected.
- Genital ulcer diseases can occur in both male and female genital areas that are covered or protected by a latex condom, as well as in areas that are not covered. Correct and consistent use of latex condoms can reduce the risk of genital herpes.
- People with herpes should abstain from sexual activity with uninfected partners when lesions or other symptoms of herpes are present. It is important to know that even if a person does not have any symptoms he or she can still infect sex partners.
- Sex partners of infected persons should be advised that they may become infected and they should use condoms to reduce the risk of infection.
- Sex partners can seek testing to determine if they are infected with HSV. A positive HSV-2 blood test most likely indicates a genital herpes infection.