Wegeners granulomatosis overview: Difference between revisions
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Wegener's granulomatosis is part of a larger group of vasculitic syndromes, all of which feature the presence of an abnormal type of circulating [[antibody]] termed [[antineutrophil cytoplasmic antibody|ANCA]]s (antineutrophil cytoplasmic antibodies) and affect small and medium-size [[blood vessel]]s. Apart from Wegener's, this category includes [[Churg-Strauss syndrome]] and [[microscopic polyangiitis]].<ref name=Seo/> Although Wegener's granulomatosis affects small and medium-sized vessels,<ref name="urlWegeners Granulomatosis: Vasculitis: Merck Manual Professional">{{cite web |url=http://www.merck.com/mmpe/sec04/ch033/ch033k.html |title=Wegener's Granulomatosis: Vasculitis: Merck Manual Professional |format= |work= |accessdate=2009-01-08}}</ref> it is formally classified as one of the small vessel vasculitides in the Chapel Hill system.<ref name="isbn0-7817-4750-3">{{cite book |author=Silva, Fred; Jennette, J. Charles; Heptinstall, Robert H.; Olson, Jean T.; Schwartz, Melvin |title=Hepinstall's pathology of the kidney |publisher=Lippincott Williams & Wilkins |location=Hagerstwon, MD |year=2007 |pages=677 |isbn=0-7817-4750-3 |oclc= |doi= |accessdate=}}</ref> | Wegener's granulomatosis is part of a larger group of vasculitic syndromes, all of which feature the presence of an abnormal type of circulating [[antibody]] termed [[antineutrophil cytoplasmic antibody|ANCA]]s (antineutrophil cytoplasmic antibodies) and affect small and medium-size [[blood vessel]]s. Apart from Wegener's, this category includes [[Churg-Strauss syndrome]] and [[microscopic polyangiitis]].<ref name=Seo/> Although Wegener's granulomatosis affects small and medium-sized vessels,<ref name="urlWegeners Granulomatosis: Vasculitis: Merck Manual Professional">{{cite web |url=http://www.merck.com/mmpe/sec04/ch033/ch033k.html |title=Wegener's Granulomatosis: Vasculitis: Merck Manual Professional |format= |work= |accessdate=2009-01-08}}</ref> it is formally classified as one of the small vessel vasculitides in the Chapel Hill system.<ref name="isbn0-7817-4750-3">{{cite book |author=Silva, Fred; Jennette, J. Charles; Heptinstall, Robert H.; Olson, Jean T.; Schwartz, Melvin |title=Hepinstall's pathology of the kidney |publisher=Lippincott Williams & Wilkins |location=Hagerstwon, MD |year=2007 |pages=677 |isbn=0-7817-4750-3 |oclc= |doi= |accessdate=}}</ref> | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[fr:Granulomatose de Wegener]] | [[fr:Granulomatose de Wegener]] | ||
[[ja:ウェゲナー肉芽腫症]] | [[ja:ウェゲナー肉芽腫症]] | ||
[[pt:Granulomatose de Wegener]] | [[pt:Granulomatose de Wegener]] | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]
Overview
Wegener's granulomatosis is a form of vasculitis that affects the lungs, kidneys and other organs. Due to its end-organ damage, it can be a serious disease that requires long-term immune suppression.[1] It is named after Dr. Friedrich Wegener, who described the disease in 1936.[2]
Wegener's granulomatosis is part of a larger group of vasculitic syndromes, all of which feature the presence of an abnormal type of circulating antibody termed ANCAs (antineutrophil cytoplasmic antibodies) and affect small and medium-size blood vessels. Apart from Wegener's, this category includes Churg-Strauss syndrome and microscopic polyangiitis.[1] Although Wegener's granulomatosis affects small and medium-sized vessels,[3] it is formally classified as one of the small vessel vasculitides in the Chapel Hill system.[4]
References
- ↑ 1.0 1.1 Seo P, Stone JH. The antineutrophil cytoplasmic antibody-associated vasculitides. Am J Med 2004;117:39-50. PMID 15210387.
- ↑ Template:WhoNamedIt
- ↑ "Wegener's Granulomatosis: Vasculitis: Merck Manual Professional". Retrieved 2009-01-08.
- ↑ Silva, Fred; Jennette, J. Charles; Heptinstall, Robert H.; Olson, Jean T.; Schwartz, Melvin (2007). Hepinstall's pathology of the kidney. Hagerstwon, MD: Lippincott Williams & Wilkins. p. 677. ISBN 0-7817-4750-3.