Lymphocytic interstitial pneumonia: Difference between revisions

	Lymphocytic interstitial pneumonia;
DiseasesDB	31904

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords: Lymphocytic interstitial pneumonitis; lymphoid interstitial pneumonitis; LIP

Overview

Lymphocytic interstitial pneumonia is a syndrome secondary to autoimmune and other lymphoproliferative disorders. Symptoms include fever, cough, and shortness of breath. Lymphocytic interstitial pneumonia applies to a disorders associated with both, monoclonal or polyclonal gammopathy.^[1]

Causes

Possible causes of lymphocytic interstitial pneumonia include

Drugs like

Diagnosis

Symptoms

Physical Examination

HEENT

Abdomen

Extremities

Clubbing

Laboratory Findings

Arterial blood gases may reveal hypoxemia.
Respiratory alkalosis may also be present.^[2]
Peripheral lymphocytosis can be observed. ^[3]

Biopsy

A lung biopsy may also be indicated.^[4]

Treatment

Patients presenting with no symptoms, and not affected by the syndrome may not require treatment. However, antibiotics are usually required for bacterial pulmonary infections. Bronchodilators may assist with breathing issues and resolution may occur with the use of Highly Active Anti-Retroviral Therapy. However, responses to different treatments are widely varied, and no single first line treatment represents the default treatment for lymphocytic interstitial pneumonia.^[5]

References

↑ The Pathology of Idiopathic Interstitial Pneumonias Carol Farver, MD
↑ Teirstein AS, Rosen MJ. Lymphocytic interstitial pneumonia. Clin Chest Med 1988;9:467-471
↑ Pitt J. Lymphocytic interstitial pneumonia. Pediatr Clin N Am 1991;38:89-95.
↑ Strimlan CV, Rosenow EC, Weiland LH, Brown LR. Lymphocytic interstitial pneumonia. Review of 13 cases. Ann Intern Med 1978;88:616-621
↑ Teirstein AS, Rosen MJ. Lymphocytic interstitial pneumonia. Clin Chest Med 1988;9:467-471

Template:Respiratory pathology

Template:WH Template:WS

[1] The Pathology of Idiopathic Interstitial Pneumonias Carol Farver, MD

[2] Teirstein AS, Rosen MJ. Lymphocytic interstitial pneumonia. Clin Chest Med 1988;9:467-471

[3] Pitt J. Lymphocytic interstitial pneumonia. Pediatr Clin N Am 1991;38:89-95.

[4] Strimlan CV, Rosenow EC, Weiland LH, Brown LR. Lymphocytic interstitial pneumonia. Review of 13 cases. Ann Intern Med 1978;88:616-621

[5] Teirstein AS, Rosen MJ. Lymphocytic interstitial pneumonia. Clin Chest Med 1988;9:467-471

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[2]

[3]

[4]

[5]

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+__NOTOC__
 {{Infobox_Disease
   | Name           = {{PAGENAME}}
@@ Line 12: / Line 13: @@
 }}
 {{CMG}}
+{{SK}} Lymphocytic interstitial pneumonitis; lymphoid interstitial pneumonitis; LIP
 ==Overview==
-'''Lymphocytic interstitial pneumonia''' (also called '''lymphocytic interstitial pneumonitis''' or '''LIP''') is a syndrome secondary to [[autoimmune]] and other [[lymphoproliferative]] disorders.  Symptoms include fever, cough, and shortness of breath.  Lymphocytic interstitial pneumonia applies to a disorders associated with both, monoclonal or polyclonal [[gammopathy]].<ref>The Pathology of Idiopathic Interstitial Pneumonias Carol Farver, MD</ref>
+Lymphocytic interstitial pneumonia is a syndrome secondary to [[autoimmune]] and other [[lymphoproliferative]] disorders.  Symptoms include fever, cough, and shortness of breath.  Lymphocytic interstitial pneumonia applies to a disorders associated with both, monoclonal or polyclonal [[gammopathy]].<ref>The Pathology of Idiopathic Interstitial Pneumonias Carol Farver, MD</ref>
 == Causes ==
-Possible causes of lymphocytic interstitial pneumonia include the [[Epstein-Barr virus]] and [[HIV|Human Immunodeficiency Virus]].
+Possible causes of lymphocytic interstitial pneumonia include
+*[[Epstein-Barr virus]],
+*[[HIV|Human Immunodeficiency Virus]]
+Drugs like
+*[[Captopril]]
+*[[Phenytoin]]
+== Diagnosis ==
-== Symptoms ==
+=== Symptoms ===
-These patients may present with
+*[[Dyspnea]]
-*[[lymphadenopathy]],
+*[[Pyrexia]]
-*[[Hepatemegaly]] Enlarged [[liver]], enlarged [[spleen]], enlarged [[salivary gland]], thickening and widening of the extremities of the fingers and toes, and breathing symptoms such as [[shortness of breath]] and wheezing.
+*[[Wheezing]]
-== Diagnosis ==
+===Physical Examination===
-[[Arterial]] blood gases may reveal [[hypoxemia]] when tested in a lab.  [[Respiratory alkalosis]] may also be present.<ref>Teirstein AS, Rosen MJ. Lymphocytic interstitial pneumonia. Clin Chest Med 1988;9:467-471</ref>  Peripheral lymphocytosis can be observed. <ref>Pitt J. Lymphocytic interstitial pneumonia. Pediatr Clin N Am 1991;38:89-95.</ref>A lung biopsy may also be indicated.<ref>Strimlan CV, Rosenow EC, Weiland LH, Brown LR. Lymphocytic interstitial pneumonia. Review of 13 cases. Ann Intern Med 1978;88:616-621</ref>
+====HEENT====
+*[[Enlarged salivary gland]]
+*[[Lymphadenopathy]]
+====Abdomen====
+*[[Hepatomegaly]]
+*[[Splenomegaly]]
+====Extremities====
+[[Clubbing]]
+===Laboratory Findings===
+*[[Arterial blood gases]] may reveal [[hypoxemia]].
+*[[Respiratory alkalosis]] may also be present.<ref>Teirstein AS, Rosen MJ. Lymphocytic interstitial pneumonia. Clin Chest Med 1988;9:467-471</ref>
+*Peripheral [[lymphocytosis]] can be observed. <ref>Pitt J. Lymphocytic interstitial pneumonia. Pediatr Clin N Am 1991;38:89-95.</ref>
+===Biopsy===
+A lung biopsy may also be indicated.<ref>Strimlan CV, Rosenow EC, Weiland LH, Brown LR. Lymphocytic interstitial pneumonia. Review of 13 cases. Ann Intern Med 1978;88:616-621</ref>
 == Treatment ==
@@ Line 35: / Line 61: @@
 {{Respiratory pathology}}
-{{SIB}}
 [[Category:Pneumonia|Pneumonia]]
 [[Category:Pulmonology]]
+[[Category:Disease]]
 {{WH}}
 {{WS}}