Acetyldigoxin: Difference between revisions

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List of terms related to Acetyldigoxin

Acetyldigoxin
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of; administration	Oral
ATC code	C01AA02 (WHO) ;
Pharmacokinetic data
Bioavailability	90%(Oral)
Protein binding	20-30%
Elimination half-life	40h
Identifiers
	IUPAC name [6-[6-[ [6-[ [12,14-dihydroxy-10,13-dimethyl-17-;
CAS Number	5511-98-8;
PubChem CID	11765960;
ChemSpider	9940650 ;
UNII	P7K44M64CW;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C43H66O15
Molar mass	822.975 g/mol
3D model (JSmol)	Interactive image;
	SMILES O=C\1OC/C(=C/1)[C@H]2CC[C@@]8(O)[C@]2(C)[C@H](O)C[C@H]7[C@H]8CC[C@H]6[C@]7(C)CC[C@H](O[C@@H]5O[C@H](C)[C@@H](O[C@@H]4O[C@@H]([C@@H](O[C@@H]3O[C@@H]([C@@H](O)[C@@H](OC(=O)C)C3)C)[C@@H](O)C4)C)[C@@H](O) C5)C6;
	InChI InChI=1S/C43H66O15/c1-20-38(49)32(55-23(4)44)18-37(52-20)58-40-22(3)54-36(17-31(40)46)57-39-21(2)53-35(16-30(39)45)56-26-9-11-41(5)25(14-26)7-8-28-29(41)15-33(47)42(6)27(10-12-43(28,42)50)24-13-34(48)51-19-24/h13,20-22,25-33,35-40,45-47,49-50H,7-12,14-19H2,1-6H3/t20-,21-,22-,25-,26+,27-,28-,29+,30+,31+,32+,33-,35+,36+,37+,38-,39-,40-,41+,42+,43+/m1/s1 ; Key:HWKJSYYYURVNQU-DXJNJSHLSA-N ;
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VisualWikitext

Latest revision as of 13:21, 14 April 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Acetyldigoxin is a cardiac glycoside. It is an acetyl derivative of digoxin. Its positive cardioinotropic effect starts after 3-4h and maximizes after 6-8h. It is prescribed for congestive chronic cardiac failure class II, III and IV.

References

@@ Line 1: / Line 1: @@
-{{drugbox
+{{Drugbox
-| IUPAC_name        = [6-[6-[ [6-[ [12,14-dihydroxy-10,13-dimethyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl]oxy]-4-hydroxyoxan-2-yl]methoxy]-4-hydroxy-2-methyloxan-3-yl]oxy-3-hydroxy-2-methyloxan-4-yl] acetate
+| verifiedrevid = 453507107
-| image             = Acetyldigoxin.png
+| IUPAC_name = [6-[6-[ [6-[ [12,14-dihydroxy-10,13-dimethyl-17-
-| CAS_number        = 5511-98-8
+| image = Acetyldigoxin.png
-| ATC_prefix        = C01
-| ATC_suffix        = AA02
+<!--Clinical data-->
-| PubChem           = 91545
+| tradename =
-| DrugBank          =
+| Drugs.com = {{drugs.com|international|acetyldigoxin}}
-| C=43|H=66|O=15
+| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
-| molecular_weight  = 822.975 g/mol
+| pregnancy_US = <!-- A / B            / C / D / X -->
-| bioavailability   =
+| pregnancy_category =
-| protein_bound     =
+| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
-| metabolism        =
+| legal_CA = <!--             / Schedule I, II, III, IV, V, VI, VII, VIII -->
-| elimination_half-life =
+| legal_UK = <!-- GSL         / P       / POM / CD / Class A, B, C -->
-| excretion         =
+| legal_US = <!-- OTC                   / Rx-only  / Schedule I, II, III, IV, V -->
-| pregnancy_AU      =  <!-- A / B1 / B2 / B3 / C / D / X -->
+| legal_status =
-| pregnancy_US      =  <!-- A / B            / C / D / X -->
+| routes_of_administration = Oral
-| pregnancy_category=
-| legal_AU          =  <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
+<!--Pharmacokinetic data-->
-| legal_CA          =  <!--             / Schedule I, II, III, IV, V, VI, VII, VIII -->
+| bioavailability = 90%(Oral)
-| legal_UK          =  <!-- GSL         / P       / POM / CD / Class A, B, C -->
+| protein_bound = 20-30%
-| legal_US          =  <!-- OTC                   / Rx-only  / Schedule I, II, III, IV, V -->
+| metabolism =
-| legal_status      =
+| elimination_half-life = 40h
-| routes_of_administration =
+| excretion =
+<!--Identifiers-->
+| CAS_number = 5511-98-8
+| ATC_prefix = C01
+| ATC_suffix = AA02
+| PubChem = 91545
+| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
+| DrugBank =
+| UNII_Ref = {{fdacite|correct|FDA}}
+| UNII = P7K44M64CW
+|  PubChem = 11765960
+|  ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
+| ChemSpiderID = 9940650
+|  smiles = O=C\1OC/C(=C/1)[C@H]2CC[C@@]8(O)[C@]2(C)[C@H](O)C[C@H]7[C@H]8CC[C@H]6[C@]7(C)CC[C@H](O[C@@H]5O[C@H](C)[C@@H](O[C@@H]4O[C@@H]([C@@H](O[C@@H]3O[C@@H]([C@@H](O)[C@@H](OC(=O)C)C3)C)[C@@H](O)C4)C)[C@@H](O)
+C5)C6
+|  InChI = 1/C43H66O15/c1-20-38(49)32(55-23(4)44)18-37(52-20)58-40-22(3)54-36(17-31(40)46)57-39-21(2)53-35(16-30(39)45)56-26-9-11-41(5)25(14-26)7-8-28-29(41)15-33(47)42(6)27(10-12-43(28,42)50)24-13-34(48)51-19-24/h13,20-22,25-33,35-40,45-47,49-50H,7-12,14-19H2,1-6H3/t20-,21-,22-,25-,26+,27-,28-,29+,30+,31+,32+,33-,35+,36+,37+,38-,39-,40-,41+,42+,43+/m1/s1
+|  InChIKey = HWKJSYYYURVNQU-DXJNJSHLBE
+|  StdInChI_Ref = {{stdinchicite|correct|chemspider}}
+| StdInChI = 1S/C43H66O15/c1-20-38(49)32(55-23(4)44)18-37(52-20)58-40-22(3)54-36(17-31(40)46)57-39-21(2)53-35(16-30(39)45)56-26-9-11-41(5)25(14-26)7-8-28-29(41)15-33(47)42(6)27(10-12-43(28,42)50)24-13-34(48)51-19-24/h13,20-22,25-33,35-40,45-47,49-50H,7-12,14-19H2,1-6H3/t20-,21-,22-,25-,26+,27-,28-,29+,30+,31+,32+,33-,35+,36+,37+,38-,39-,40-,41+,42+,43+/m1/s1
+|  StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
+| StdInChIKey = HWKJSYYYURVNQU-DXJNJSHLSA-N
+<!--Chemical data-->
+| C=43 | H=66 | O=15
+| molecular_weight = 822.975 g/mol
 }}
+__NOTOC__
 {{SI}}
 {{CMG}}
-{{Editor Join}}
 ==Overview==
-'''Acetyldigoxin''' is a [[cardiac glycoside]].  It is an [[acetyl]] derivative of [[digoxin]].
+'''Acetyldigoxin''' is a [[cardiac glycoside]].  It is an [[acetyl]] derivative of [[digoxin]]. Its positive cardioinotropic effect starts after 3-4h and maximizes after 6-8h. It is prescribed for congestive chronic cardiac failure class II, III and IV.
-{{Cardiac glycosides}}
+==References==
+{{reflist|2}}
 [[Category:Cardiac glycosides]]
-[[Category:Drugs]]
+[[Category:Cardiovascular Drugs]]
+[[Category:Drug]]
-{{WikiDoc Help Menu}}
-{{WikiDoc Sources}}

Clinical data

AHFS/Drugs.com	International Drug Names
Routes of administration	Oral
ATC code	C01AA02 (WHO)
Pharmacokinetic data
Bioavailability	90%(Oral)
Protein binding	20-30%
Elimination half-life	40h
Identifiers
IUPAC name [6-[6-[ [6-[ [12,14-dihydroxy-10,13-dimethyl-17-
CAS Number	5511-98-8
PubChem CID	11765960
ChemSpider	9940650^Y
UNII	P7K44M64CW
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₄₃H₆₆O₁₅
Molar mass	822.975 g/mol
3D model (JSmol)	Interactive image
SMILES O=C\1OC/C(=C/1)[C@H]2CC[C@@]8(O)[C@]2(C)[C@H](O)C[C@H]7[C@H]8CC[C@H]6[C@]7(C)CC[C@H](O[C@@H]5O[C@H](C)[C@@H](O[C@@H]4O[C@@H]([C@@H](O[C@@H]3O[C@@H]([C@@H](O)[C@@H](OC(=O)C)C3)C)[C@@H](O)C4)C)[C@@H](O) C5)C6
InChI InChI=1S/C43H66O15/c1-20-38(49)32(55-23(4)44)18-37(52-20)58-40-22(3)54-36(17-31(40)46)57-39-21(2)53-35(16-30(39)45)56-26-9-11-41(5)25(14-26)7-8-28-29(41)15-33(47)42(6)27(10-12-43(28,42)50)24-13-34(48)51-19-24/h13,20-22,25-33,35-40,45-47,49-50H,7-12,14-19H2,1-6H3/t20-,21-,22-,25-,26+,27-,28-,29+,30+,31+,32+,33-,35+,36+,37+,38-,39-,40-,41+,42+,43+/m1/s1^Y Key:HWKJSYYYURVNQU-DXJNJSHLSA-N^Y
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Acetyldigoxin: Difference between revisions

Latest revision as of 13:21, 14 April 2015

Overview

References

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